How Much Does Genetic Testing Cost? 11 Whole-Genome Sequencing and DNA Tests Compared
How much a genetic test costs across 11 whole-genome sequencing and DNA testing providers, comparing sequencing depth, test type, availability, and membership pricing where applicable.
Quick Summary
Genetic tests range from low-cost ancestry kits to more comprehensive whole-genome sequencing. This guide compares 11 options by price, test type, depth, best use case, and availability so you can see what you actually get before ordering. Mito offers 3x whole-genome sequencing and 30x whole-genome sequencing for educational and wellness use, not diagnosis or treatment decisions.
The Genetic Testing Market in 2026
Before comparing brands, separate the job you want the test to do:
- Whole-genome sequencing for health-oriented context: Best when you want durable genome files, broader variant coverage, and the option to revisit your data as science improves.
- Genotyping arrays for mainstream health and traits: Lower cost and easier reports, but they check a selected set of sites instead of reading across the genome.
- Ancestry and genealogy testing: Best for ethnicity estimates, DNA relatives, family trees, Y-DNA, mtDNA, or deep lineage research.
- Upload and interpretation tools: Best if you already have raw DNA data and want more reports, but these tools do not create new sequencing data.
- Clinical genetic labs: Best when a clinician is evaluating a personal or family history, a suspected rare disease, hereditary cancer risk, or a medication-response question.
Mito is not trying to be an ancestry matching database or a diagnostic genetics lab. The practical question is whether you want a genome file you can own and use as one layer of preventive health context.
Genetic Testing Competitor Comparison
Advertised genetic test prices, August 2026. Mito pricing below uses current member pricing. Some providers list one-time kit prices, while others require subscriptions or memberships. Prices change often, verify on each provider before relying on them.
You can order Mito whole-genome sequencing as a 3x or 30x test. Compare Mito 3x and 30x WGS.
Brand | Pricing | Test type | Depth / coverage | Best for | Availability |
|---|---|---|---|---|---|
Mito Health | Whole-genome sequencing | 3x or 30x WGS | Genome ownership, traits, ancestry, health-oriented inherited context | United States (except Texas) | |
Nucleus Health | 30x: $499 | Whole-genome sequencing | 30x WGS | Broad health-risk screening and carrier context in a consumer app | United States and select international countries |
DNA Complete by Nebula Genomics | 1x: $245 | Whole-genome sequencing | 1x, 30x, or 100x WGS tiers | Health reports, ancestry, monthly report updates, and high-depth options | United States and international shipping |
Sequencing.com | 30x: $399+ | Whole-genome sequencing plus DNA report marketplace | 30x WGS bundles | Raw data files, report apps, rare-disease and carrier-screening bundles | Worldwide shipping |
Dante Labs | 30x: $449+ | Whole-genome sequencing | 30x WGS | Health reports, physician-ready outputs, and global WGS access | Worldwide shipping |
23andMe Health + Ancestry | Premium Ancestry + Health: $199 | Genotyping array | Selected sites, not WGS | Mainstream ancestry, carrier-status reports, genetic health-risk reports, wellness traits | United States, Canada, United Kingdom, select EU countries, and ancestry-only international markets |
MyHeritage DNA | DNA kit: $89 | Consumer DNA for genealogy, now using WGS for new DNA kits | WGS positioned for matching and ethnicity accuracy | Ancestry, ethnicity, DNA relatives, international genealogy | Most countries except restricted locations |
AncestryDNA + Traits | AncestryDNA: $99 | Autosomal DNA test with traits | Not WGS | Ethnicity, family matching, family trees, and 100+ traits | 100+ countries |
FamilyTreeDNA | Family Finder: $39 | Autosomal, Y-DNA, and mtDNA genealogy tests | Lineage-specific tests, not health WGS | Direct paternal lineage, direct maternal lineage, surname projects, genealogy research | Most countries except restricted locations |
SelfDecode | DNA kit: $99 | DNA interpretation and health reports; upload or kit workflows | Depends on uploaded or ordered source data | Turning existing raw DNA files into health and wellness reports | Most countries and territories worldwide; digital uploads available |
Color Health | Extended: $299 | Targeted clinical genetic testing | Targeted genes, not WGS | Hereditary cancer, hereditary heart health, medication response, clinician follow-up | United States, program dependent |
Whole-Genome Sequencing vs. DNA Kits
Most consumer DNA products fall into two broad categories: whole-genome sequencing and genotyping array DNA kits.
Whole-genome sequencing reads broadly across your DNA. The result is a more complete genome dataset that can be revisited as science improves. Depth matters here. A lower-depth genome, like 3x WGS, can be useful for ancestry, traits, polygenic scores, and genome ownership. A higher-depth genome, like 30x WGS, is better suited for health-oriented inherited context because it improves confidence for rare variants, carrier-status context, ClinVar-linked findings, and pharmacogenomics context.
Genotyping array DNA kits are different. Products like 23andMe and AncestryDNA check selected genetic markers rather than reading the whole genome. That can work well for ancestry matching, traits, and some mainstream health reports, especially when the company has a large relative-matching database. The tradeoff is that an array does not give you the same breadth of raw genome data as whole-genome sequencing.
Genealogy tests are a third practical category. MyHeritage, AncestryDNA, and FamilyTreeDNA are often the better fit when the goal is ethnicity estimates, DNA relatives, family trees, Y-DNA, mtDNA, or surname projects. They can be useful even if they are not health-oriented WGS products.
Clinical genetic panels are different again. Color Health, GeneDx, Invitae/Labcorp, and Mayo Clinic Labs are closer to clinician-ordered genetics for a specific medical question. That workflow is not the same as buying a consumer genome test for educational or wellness context.
Where Mito Health Fits
Mito’s main advantage is context. Whole-genome sequencing is not isolated from the rest of your health data. It can sit alongside bloodwork, imaging, microbiome testing, family history, medications, symptoms, and goals.
The 3x option is the lower-cost way to own true whole-genome data. It is best for ancestry, traits, polygenic scores, common variants, and exploration.
The 30x option is the stronger default for health-oriented buyers. At this depth, the data is better suited for rare and pathogenic variant confidence, carrier-status context, ClinVar-linked findings, and pharmacogenomics context.
Mito also draws a hard boundary around interpretation. Genetic data is powerful context. It is not a diagnosis, a medication instruction, or a substitute for a clinician or genetic counselor.
How to Choose a Genetic Test
Choose whole-genome sequencing if you want broad genome data that you can own and revisit later. It is the better fit when your goal is long-term genome ownership, health-oriented inherited context, or future reanalysis as interpretation improves.
Choose 3x whole-genome sequencing if you want the lower-cost way to own true whole-genome data. It is best for ancestry, traits, polygenic scores, common variants, and general genome exploration.
Choose 30x whole-genome sequencing if you want stronger data for health-oriented inherited context. At this depth, the data is better suited for rare and pathogenic variant confidence, carrier-status context, ClinVar-linked findings, and pharmacogenomics context.
Choose a mainstream DNA kit if your main goal is ancestry, relatives, traits, or a simple consumer health-report experience. These tests are usually cheaper than WGS because they check selected markers instead of sequencing broadly across the genome.
Choose a DNA interpretation service if you already have raw DNA data and want additional reports. Upload tools can interpret an existing file, but they do not create new sequencing data.
Choose a clinical genetic test if a clinician is evaluating a personal or family history, inherited cancer risk, heart condition, rare disease, medication-response question, or another specific medical concern. Clinical testing is a different category from educational consumer genetics.
Frequently Asked Questions
Is whole-genome sequencing the same as an ancestry DNA kit?
No. Whole-genome sequencing is more comprehensive because it reads broadly across your DNA. Many ancestry DNA kits use genotyping arrays, which check selected genetic markers for ethnicity estimates, DNA relatives, traits, and some consumer health reports.
Should I choose 3x or 30x whole-genome sequencing?
Choose 3x if you mainly want ancestry, traits, polygenic scores, and lower-cost genome ownership. Choose 30x if your main goal is health-oriented inherited context and better confidence for rare variants, carrier-status context, ClinVar-linked findings, and pharmacogenomics context. See the full 3x vs. 30x guide.
Is Mito’s genome product a medical test?
No. Mito’s genetic services are educational and wellness-oriented. Do not use them to diagnose a condition, make treatment decisions, or change a medication without a qualified clinician or genetics professional.
Related resources
- 3x vs. 30x Whole-Genome Sequencing
- Whole-Genome Sequencing With Mito Health
- Your Genome Should Stay Yours
- Mito Health vs. Lab Testing Competitors
- Mito Health vs. InsideTracker
References
- Genome Computer FAQ
- Nucleus Health
- DNA Complete by Nebula Genomics
- DNA Complete Terms of Use
- Sequencing.com Whole Genome Sequencing Kit
- Sequencing.com Shipping and Handling
- Dante Labs Genome Test
- Dante Labs FAQ
- 23andMe Health Reports
- 23andMe Shipping Countries
- MyHeritage Whole Genome Sequencing Announcement
- MyHeritage DNA Eligibility
- AncestryDNA Traits
- AncestryDNA FAQ
- FamilyTreeDNA
- FamilyTreeDNA Availability
- SelfDecode
- SelfDecode Shipping
- Color Extended Genetic Test
- GeneDx
Medical Disclaimer
This comparison is for informational purposes only and does not constitute medical advice. Genetic testing features, pricing, privacy policies, availability, and report scope can change. Verify current details directly with each provider before ordering. Genetic results should not be used to diagnose, treat, prevent, or make decisions about a medical condition without a qualified clinician or genetics professional.