LucenceINSIGHT Core
Add a blood-based screen for molecular signals associated with six cancers.
- No doctor visit or referral needed
- Members pay our cost on every test, never a markup
- Tracked over time alongside your other results
- Typical results in about 18 working days · Reviewed by a real clinician
- At-home blood draw included
Why people order the LucenceINSIGHT Core
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An additional screening layer
This may complement guideline screening, especially for covered cancers without routine population screening, but it does not replace established tests.
Who may consider the LucenceINSIGHT Core
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Personal or family history
History involving covered cancers may support a conversation about an added blood-based screening layer, but the test cannot diagnose cancer.
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Clinician-guided screening decision
A clinician can help assess fit, exclusions, and the right response to either a detected signal or no signal detected.
Is this appropriate if I have symptoms, a current cancer diagnosis, or need treatment monitoring?
No. Use a clinician-directed diagnostic or monitoring pathway. LucenceINSIGHT is a screening aid for people without a current cancer diagnosis.
Can this replace mammography, colonoscopy, low-dose CT, cervical screening, or other guideline screening?
No. Continue every guideline-recommended screening test that applies to you. LucenceINSIGHT adds a blood-based layer and does not replace imaging, endoscopy, cytology, or biopsy.
Should I use this for inherited cancer risk?
No. The test looks for acquired molecular signals in cell-free DNA, not germline variants. Choose clinician-guided hereditary cancer testing for inherited-risk questions.
Does Core cover the cancers I am concerned about?
Core covers lung, colorectal, liver, pancreatic, thyroid, and breast cancers. Choose another pathway if your main concern falls outside those six.
Where is this test available?
This test is available nationwide except Pennsylvania, New York, and Rhode Island.
How should I prepare for the blood draw?
Fasting is not required. Avoid a heavy meal before your draw. Have your blood drawn in the comfort of your home at no additional cost. Tell your care team about recent surgery, blood transfusion, or bone marrow transplant, or pregnancy so they can confirm timing and eligibility.
What members say on Trustpilot
What the LucenceINSIGHT Core measures
LucenceINSIGHT Core is a blood-based liquid-biopsy screening aid for molecular signals associated with lung, colorectal, liver, pancreatic, thyroid, and breast cancers. It analyzes cell-free DNA for acquired changes and may predict a likely tissue of origin when a signal is found.
The Core gene scope is ACVR2A, AKT1, ALK, AMER1, APC, ARID1A, ATM, BMPR2, BRAF, BRCA1, BRCA2, CBFB, CDH1, CDKN1B, CDKN2A, CTNNB1, EGFR, ERBB2 (HER2), ERBB3, ESR1, FBXW7, FOXA1, GATA3, GNAS, KEAP1, KRAS, MEN1, MET, MSH6, NF1, NFE2L2, NRAS, PCBP1, PIK3CA, PPP2R1A, PTEN, RET, RIT1, RNF43, RPL22, SMAD4, STK11, TCF7L2, TERT promoter, TGFBR2, and TP53.
The current US offering does not include ctRNA boost or gene-fusion reporting. ctRNA arrives with the INSIGHT 50 upgrade. Core does not diagnose cancer, assess inherited risk, or replace guideline screening or evaluation of symptoms.
- Specimen
- Blood sample
- Cancer scope
- 6 cancers
- Fasting
- Not required
- Results
- On your Mito dashboard in about 18 working days, with your range explained
Your results
How to understand your LucenceINSIGHT Core result
Interpret either result with the covered cancer scope, personal risk, symptoms, and guideline screening. The current US offering does not include ctRNA boost or gene-fusion reporting. ctRNA arrives with the INSIGHT 50 upgrade.
No signal detected
The assay did not identify a reportable molecular signal in the covered scope. This is reassuring but does not rule out cancer. Detection varies by cancer type and stage, so routine screening and symptom evaluation remain necessary.
Signal detected
The assay identified a molecular pattern associated with cancer and may suggest a likely tissue of origin. This is not a diagnosis. Follow-up may include clinical assessment, imaging, endoscopy, or biopsy to confirm and locate a cause.
How much the LucenceINSIGHT Core costs
Compare exact Mito member and non-member prices with recently checked comparable offers. Collection and lab fees are shown separately.
| Lab | Test price | Collection or lab fee |
|---|---|---|
| Mito member | $430.92 | $0.00 Added once per order |
| Mito non-member | $603.29 | $0.00 Added once per order |
Mito prices come from the live catalog for the selected provider.
How it works
What to expect from your LucenceINSIGHT Core
- 1 Book instantly
Click, book, done. There is no lab to choose.
- 2 Home kit and draw
Your kit is delivered and your at-home blood draw is set up for you.
- 3 Results in about 18 working days
Your result posts straight to your Mito dashboard when it is ready.
- 4 Expert guidance
A clinician reviews your result and helps coordinate follow-up if a cancer signal is detected.
Every result comes with a plan
A number on its own does not tell you much. Membership is what turns it into next steps, and keeps track of what changes.
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
LucenceINSIGHT Core testing you can trust
Run to clinical-grade standards
- Processed at the same CLIA and CAP-accredited national labs your doctor uses
- Order online, no doctor visit or referral needed
- Your data is encrypted, handled under HIPAA, and never sold
Overseen by our Care Team Lead
Every result, including your Mito Brain analysis, is checked by Rhonda Collins, FNP-C, our Care Team Lead and a board-certified Family Nurse Practitioner with over 15 years of nursing experience across cardiac ICU, primary care, and dermatology.
Meet RhondaWhat members are saying
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@nasdaily
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15/10 experience - I felt actually taken care of
Super impressed with my Mito experience - the thoroughness of the intake, the data tracking and the doctor's visit.
RS Reena Sudan -
@ellarosemcfadin
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Helped show an overall picture
I would highly recommend this service to anyone that wants a more in-depth picture of their health and labs. The platform is super user friendly.
BS Bo Sal -
@katelyn_kim
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Specific and actionable advice
It felt like, for the first time, I had real data guiding me to make meaningful changes and I've definitely noticed the difference.
MH Maya Hickey -
@bryce_witmer
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Tired of arguing with my PCP
After extensive research, I decided Mito was the best option. The insights were clear and make sense. Mito gave me peace of mind and a path to follow.
JO Josh -
@alexandradawson
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3x the tests for less money
A great alternative to the basic blood work at your local clinic. Love the report card format. Much better value.
P Page -
@daniklass
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Best $9 a month I spend
The action plan changes every time new results come in. I've actually never had a health company recommend doing less. Refreshing.
DP Devi Patel -
@natalieefer
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Finally, prices that make sense
Every test is published. I can see what it costs and what I save as a member. No surprises.
KT Kenji Tanaka -
@tyler_sarkisian
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
Common LucenceINSIGHT Core questions
What does LucenceINSIGHT measure?
What does no signal detected mean?
What does signal detected mean?
Does this test replace guideline screening?
Does it include ctRNA boost or gene-fusion reporting?
Does HPV detection mean this screens for cervical cancer?
Can a blood test find every cancer at every stage?
What happens after a detected signal?
Is this an inherited cancer-risk test?
How does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the membership, not on marking up your tests. Membership is $9 per month or $99 per year, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Mito's lab tests are HSA/FSA eligible, so you can pay with pre-tax dollars.
Add the test to your cart and select "Pay with HSA/FSA" at checkout. You'll finish on the secure checkout page of Flex, our HSA/FSA payments partner, and Flex emails you an itemized receipt from notifications@withflex.com for your records.
Most Mito tests are auto-substantiated, so you usually won't need a Letter of Medical Necessity. If your HSA/FSA administrator asks for more, contact us and we'll help.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.