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High-Sensitivity C-Reactive Protein

2 mg/L
Blood test

C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test

Add an inflammation-sensitive signal to a complete cardiovascular risk assessment.

$5.94 Member price Member price with the $9/month membership. Plus a one-time lab draw fee, passed through at cost. $8.32 Non-member
Excellent 4.8 out of 5
  • No doctor visit or referral needed
  • Members pay our cost on every test, never a markup
  • Tracked over time alongside your other results
  • HSA/FSA eligible
  • Typical results in 1 day · Reviewed by a real clinician
  • Drawn at a CLIA/CAP-accredited lab near you · Find labs

Why people order the C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test

  • Add an inflammation-sensitive signal to cardiovascular risk assessment

    The result complements lipids, blood pressure, glucose-related markers, smoking history, and family history rather than replacing them.

  • Establish a comparable baseline while clinically stable

    Testing outside an acute illness or inflammatory event makes the result more useful for long-term cardiovascular context.

  • See whether an elevation persists when repeat testing is appropriate

    Serial results may help distinguish a persistent signal from a transient rise, but there is no universal repeat schedule.

Who may consider the C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test

  • Borderline cardiovascular risk where another risk enhancer may help

    A clinically stable hs-CRP result can add an inflammation-sensitive signal when a clinician is deciding how to interpret an otherwise borderline risk estimate.

  • Family history of premature cardiovascular disease or other established risk factors

    hs-CRP can add context that is not captured by one lipid value, but it does not replace the standard cardiovascular risk assessment.

  • Confirm a prior elevation after acute inflammation has been considered

    Infection, injury, surgery, or an inflammatory flare can raise CRP. Repeat timing and the need for retesting depend on the value and clinical purpose.

  • Assess residual inflammatory risk with known cardiovascular disease

    This is a clinician-directed use that must be interpreted with treatment status and the complete cardiovascular picture.

Is hs-CRP the right test for cardiovascular risk, or do I need standard CRP?

Choose hs-CRP when the goal is low-range cardiovascular-risk context. Standard CRP is generally used for more prominent or broader inflammation and is a different product. Neither test identifies the source of inflammation by itself.

Should I add hs-CRP if I already have a lipid panel?

It can add complementary context for selected cardiovascular-risk questions. A lipid panel describes cholesterol patterns, while hs-CRP is an inflammation-sensitive risk signal. hs-CRP does not replace lipid testing or a broader cardiovascular-risk assessment.

Is hs-CRP appropriate as a general wellness screening test?

Not as a universal standalone screen. It is most useful when there is a defined cardiovascular-risk question and the result will be interpreted with established risk factors. It cannot diagnose heart disease or locate inflammation.

Should I delay testing after an illness, injury, surgery, or inflammatory flare?

Usually yes when the goal is a stable cardiovascular baseline. Recent infection, injury, surgery, or an inflammatory flare can temporarily raise hs-CRP and obscure the intended signal. Follow clinician guidance if the test is being ordered for another reason or if timing is uncertain.

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What the C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test measures

Add an inflammation-sensitive signal to a complete cardiovascular risk assessment.

This test measures C-reactive protein at low concentrations using a high-sensitivity assay. CRP is an acute-phase protein produced by the liver in response to inflammation. The high-sensitivity method is used for cardiovascular-risk context because it can resolve lower concentrations than a standard CRP assay.

The product returns one hs-CRP result in mg/L from serum or plasma obtained through venous collection. It does not identify where inflammation is occurring, establish its cause, diagnose cardiovascular disease, or replace a standard lipid profile, blood pressure assessment, diabetes evaluation, smoking history, family history, or the clinician's overall risk assessment.

Current US guidance gives hs-CRP a narrow clinical role rather than treating it as a universal screening score. The 2026 ACC/AHA multisociety dyslipidemia guideline states that, in adults without ASCVD who have borderline 10-year risk by the PREVENT-ASCVD equations, an hs-CRP result of at least 2 mg/L on two successive occasions with no identifiable underlying cause can inform a clinician-managed lipid-lowering decision. That guideline threshold is not a laboratory reference interval and does not apply automatically to every buyer.

Specimen
Serum or plasma
Method
High sensitivity
Measures
Mass concentration
Reported biomarkers
hs-CRP
Biomarker count
1 biomarker
Fasting
Special preparation needed (test when clinically stable)
Results
On your Mito dashboard in 1 day, with your range explained
Provider reference information
Quest Diagnostics Test 10124 selected Labcorp Test 120766

Quest Diagnostics Test 10124

  • Optimal <1.0 mg/L
  • Lower relative cardiovascular risk <1.0 mg/L
  • Average relative cardiovascular risk 1.0-3.0 mg/L
  • Higher relative cardiovascular risk 3.1-10.0 mg/L
  • Persistent elevation after retesting may reflect infection or inflammation >10.0 mg/L

Labcorp Test 120766

  • Low cardiovascular risk <1.00 mg/L
  • Average cardiovascular risk 1.00-3.00 mg/L
  • High cardiovascular risk >3.00 mg/L

Your results

How to understand your C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test result

Use the cardiovascular category on the performing laboratory's report. Provider categories, the current guideline threshold of at least 2 mg/L for a narrowly defined clinical decision, and individualized treatment goals are different concepts. Cardiovascular interpretation is intended for clinically stable adults.

Lower cardiovascular-risk context

A lower hs-CRP result means less cardiovascular risk attributable to this inflammation-sensitive signal. It does not rule out high LDL cholesterol, high ApoB, high Lp(a), hypertension, diabetes, smoking-related risk, family history, or existing plaque.

Elevated cardiovascular-context result

An elevation can add risk information when you are clinically stable and the result is interpreted with your complete cardiovascular profile. One result does not show that inflammation is located in the arteries, identify its cause, or by itself determine treatment.

Possible acute or noncardiovascular elevation

Infection, injury, an inflammatory flare, surgery, or another tissue-injury event can raise hs-CRP. A very high or unexpected result should be evaluated for those causes before it is used as a cardiovascular-risk signal. A clinician may recommend repeat testing once you are stable.

How much the C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test costs

Compare exact Mito member and non-member prices with recently checked comparable offers. Collection and lab fees are shown separately.

Lab Test price Collection or lab fee
Mito member $5.94 $15.00 Added once per order
Mito non-member $8.32 $15.00 Added once per order
Goodlabs $9.00 $12.00 $12 per visit, included in the final checkout total
Marek Diagnostics $18.50 $10.00 $10 added at checkout for an individual biomarker or custom panel
DrSays $13.99 $9.99 $9.99 collection fee per order
Jason Health $20.00 $18.00 $18 lab collection fee per order
Ulta Lab Tests $36.95 $12.95 $12.95 standard draw fee; some locations may charge more
Walk-In Lab $41.00 $6.00 $6 per-order physician fee

Mito prices come from the live catalog for the selected provider. Competitor prices were checked August 22, 2026. Published standalone item price plus the separately disclosed collection or checkout fee.

See the full C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test cost comparison for provider details and comparison notes.

How it works

What to expect from your C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test

  1. 1 Book instantly

    Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.

  2. 2 Quick lab visit

    Testing to fit your schedule, usually 15 minutes or less. Walk-in and appointments available. Follow the preparation instructions for your order.

  3. 3 Results in 1 day

    Your result posts straight to your dashboard as soon as the lab completes it.

  4. 4 Expert guidance

    With membership, a clinician reviews your result and a personalized action plan follows, with clear next steps.

Mito dashboard showing biological age, health categories, biomarkers, and health trends

Every result comes with a plan

A number on its own does not tell you much. Membership is what turns it into next steps, and keeps track of what changes.

  • Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.

  • Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.

  • Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.

  • Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.

Accredited and reviewed

C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test testing you can trust

Run to clinical-grade standards

CLIA certified
CAP accredited
HIPAA compliant
  • Processed at the same CLIA and CAP-accredited national labs your doctor uses
  • Order online, no doctor visit or referral needed
  • Your data is encrypted, handled under HIPAA, and never sold
Rhonda Collins, FNP-C, Mito Care Team Lead
Clinician-reviewed

Overseen by our Care Team Lead

Every result, including your Mito Brain analysis, is checked by Rhonda Collins, FNP-C, our Care Team Lead and a board-certified Family Nurse Practitioner with over 15 years of nursing experience across cardiac ICU, primary care, and dermatology.

Meet Rhonda

Everything your health needs,
in one membership

  • A Mito member relaxing at home, checking their results on their phone

    Every test at our cost

    Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.

  • Mito dashboard on a tablet showing biomarker results and trends

    Continuous tracking, all in one place

    Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.

  • A Mito clinician checking in with a member over text messaging

    Year-round clinician support

    Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.

Common C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test questions

What does an hs-CRP test measure?
It measures very low concentrations of C-reactive protein, an acute-phase protein produced by the liver in response to inflammation.
How is hs-CRP different from standard CRP?
The high-sensitivity method resolves lower concentrations used in cardiovascular-risk assessment. Standard CRP is used more broadly for clinically apparent inflammation.
Can hs-CRP diagnose heart disease?
No. It can add information to a broader risk assessment but cannot diagnose plaque, a blocked artery, a heart attack, or another cardiovascular condition.
What do the Labcorp and Quest categories mean?
They are provider-authored cardiovascular-risk categories for those assays. They are not universal normal ranges or individualized treatment goals.
Why does the current ACC/AHA guideline mention 2 mg/L?
The guideline treats a persistent result at or above 2 mg/L as a risk enhancer. Its treatment recommendation applies to a defined borderline-risk population after two successive elevations and exclusion of another cause.
Can illness, injury, or inflammation affect the result?
Yes. CRP is nonspecific, so infection, inflammatory disease, recent tissue injury, or another acute event can raise it independently of long-term cardiovascular risk.
What does a result above 10 mg/L mean?
It is not a cardiovascular diagnosis. Quest says persistent elevation after retesting may be associated with infection or inflammation. A clinician should interpret the result and its timing.
Do I need to fast?
Quest's checked test data states that fasting is not required. Labcorp 120766 publishes no fasting instruction. Follow the preparation instructions for the complete order because another test may require fasting.
Should an elevated result be repeated?
Sometimes. The appropriate timing and purpose depend on the value, provider context, recent illness, and clinical decision. One universal repeat rule is not appropriate.
Which tests add context to hs-CRP?
A standard lipid panel, ApoB, Lp(a), blood pressure, glucose-related markers, smoking history, family history, and clinical assessment provide complementary cardiovascular context.
How do availability and prices vary by state?

Available in all 50 states and Washington, DC.

State availability and member and non-member prices for C-Reactive Protein, High Sensitivity (hs-CRP) Blood Test
States Provider Availability Member price Non-member price
All states and DC except NJ, NY, and RI Labcorp Available $10.49 $14.69
All states and DC except NJ, NY, and RI Quest Diagnostics Available $5.94 $8.32
NJ, NY, and RI BioReference Available $11.18 $15.66

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