Trimethylamine N-Oxide (TMAO)
A gut-derived metabolite linked to atherosclerosis and cardiovascular risk.
Consider this test if:
- Building a cardiovascular-prevention plan and want a marker tied to diet and gut metabolism
- A diet heavy in red meat, egg yolk, or full-fat dairy alongside other heart-risk factors
- Family history of heart disease and looking beyond standard cholesterol numbers
- Tracking whether a shift toward a more plant-based diet changes your metabolic profile
- Already managing cardiovascular risk and adding context to ApoB and hs-CRP
- HSA/FSA eligible
- Typical results in 3-5 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
Fast overnight, ideally 10 to 12 hours. Avoid fish and other marine foods the day before the draw, since they raise TMAO directly and can distort the result. Because the level tracks recent diet, keep your eating pattern typical in the days before testing if you want a representative baseline.
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A 1:1 call to discuss your health.
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What this test is for
TMAO is a compound your body produces in two steps: gut bacteria break down choline, lecithin, and L-carnitine from animal foods like red meat, egg yolk, and full-fat dairy into TMA, which the liver then converts to TMAO. Elevated TMAO has been linked to the development of atherosclerosis and to higher cardiovascular risk, independent of standard cholesterol numbers. It sits at the intersection of diet, gut microbiome composition, and heart health, which makes it useful both for people refining a cardiovascular-prevention strategy and for those curious how their diet and gut bacteria translate into a measurable metabolite. The level reflects recent diet and your individual microbial population, so it shifts with eating patterns rather than being a fixed trait. It adds context to a cardiovascular workup but is read alongside ApoB, LDL, hs-CRP, and overall risk rather than on its own.
- Specimen
- Serum or plasma
- Method
- Mass spectrometry (LC-MS/MS)
- Measures
- Substance concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 3-5 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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$9 /mo
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Without membership
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.
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