Tissue Transglutaminase (tTG) Antibodies (IgG, IgA) Panel
The primary blood screen for celiac disease, covering both antibody classes in one panel.
Consider this test if:
- Chronic diarrhea, bloating, abdominal pain, or unexplained weight loss
- Iron-deficiency anemia, fatigue, or low vitamin levels with no clear cause
- A close relative has celiac disease or you have type 1 diabetes or thyroid autoimmunity
- An itchy, blistering skin rash suggestive of dermatitis herpetiformis
- Known or suspected IgA deficiency, where the IgG result becomes especially important
- HSA/FSA eligible
- Results delivered to your dashboard · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No fasting required. Keep eating gluten normally before testing: cutting gluten lowers these antibodies and can produce a false negative, so do not start a gluten-free diet until testing is complete.
Video consult with your Care Team
A 1:1 call to discuss your health.
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What this test is for
Tissue transglutaminase (tTG) antibodies are produced when gluten triggers an immune reaction in people with celiac disease, damaging the lining of the small intestine. This panel measures both the IgA and IgG classes: tTG-IgA is the main screening marker for celiac disease and dermatitis herpetiformis, while tTG-IgG adds value in people who are IgA-deficient, where the IgA test can read falsely negative. High levels point toward gluten-sensitive enteropathy and prompt confirmation, usually with endoscopic biopsy. It is commonly checked when investigating chronic diarrhea, bloating, weight loss, iron-deficiency anemia, fatigue, or an itchy blistering rash, and to screen relatives of someone with celiac disease.
Pairing both classes is useful because it covers the roughly 2 to 3 percent of celiac patients who are IgA-deficient, a group a single IgA test alone can miss.
Biomarkers tested
Includes 2 biomarkers
- Specimen
- Serum
- Measures
- Concentration
- Specimen
- Serum
- Measures
- Concentration
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Fast, dashboard-delivered results
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
cancel anytime
Without membership
$0
pay as you go
At-cost pricing on labs, scans, and more
Priority turnaround on your results
On-demand clinician consults when you need guidance
Personalized action plans across supplements, exercise, nutrition, and sleep
AI health coaching to help you act on your results
Year-round medical support, with in-chat clinician escalation
All your health records in one personal vault, with trends and biological age tracking
Early access to new diagnostics and product releases
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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