Tissue Transglutaminase Antibody (IgG)
An antibody marker for celiac disease, especially useful when IgA testing falls short.
Consider this test if:
- Bloating, diarrhea, weight loss, or fatigue that points toward celiac disease
- Known or suspected IgA deficiency, where the standard tTG IgA screen is unreliable
- Iron-deficiency anemia or unexplained nutrient malabsorption
- A first-degree relative with celiac disease and you want screening
- Tracking antibody levels after a celiac diagnosis to gauge dietary adherence
Currently unavailable in your state.
This test isn't offered by labs in your state yet.
Pre-test considerations
No fasting required. Keep eating a normal gluten-containing diet in the weeks before testing, because cutting gluten lowers these antibodies and can mask celiac disease. If you are already gluten-free, discuss timing before testing, since results may be falsely low.
Video consult with your Care Team
A 1:1 call to discuss your health.
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What this test is for
Tissue transglutaminase (tTG) IgG is an antibody the immune system produces in celiac disease, an autoimmune reaction to gluten that damages the small intestine and can cause bloating, diarrhea, weight loss, fatigue, iron deficiency, and poor nutrient absorption. The IgA version of this antibody is the standard first-line celiac screen for most people, but it is unreliable in those with selective IgA deficiency, which is more common in celiac disease than in the general population. This IgG form is the right test in that situation, giving a useful celiac signal when total IgA is low. A positive result raises suspicion for celiac disease and is typically confirmed with additional antibody testing and an intestinal biopsy. Keep eating gluten before testing, since a gluten-free diet lowers these antibodies and can produce a falsely negative result.
- Specimen
- Serum
- Method
- Immunoassay
- Measures
- Concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in about 3 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
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Without membership
$0
pay as you go
At-cost pricing on labs, scans, and more
Priority turnaround on your results
On-demand clinician consults when you need guidance
Personalized action plans across supplements, exercise, nutrition, and sleep
AI health coaching to help you act on your results
Year-round medical support, with in-chat clinician escalation
All your health records in one personal vault, with trends and biological age tracking
Early access to new diagnostics and product releases
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a doctor's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate doctor visit before purchasing.
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