Tissue Transglutaminase Antibodies (IgG, IgA) Panel
The first-line blood test for celiac disease, covering the case standard screening can miss.
Consider this test if:
- Chronic GI symptoms like diarrhea, bloating, abdominal pain, or unexplained weight loss
- Iron-deficiency anemia, fatigue, or nutrient deficiencies without a clear cause
- A first-degree relative with celiac disease or another autoimmune condition such as type 1 diabetes or thyroid disease
- Screening when IgA deficiency is known or suspected, where an IgA-only test can read falsely normal
- Investigating symptoms that improve on a gluten-free diet, before committing to lifelong dietary change
Currently unavailable in your state.
This test isn't offered by labs in your state yet.
Pre-test considerations
No fasting required. Critically, keep eating a normal gluten-containing diet in the weeks before testing. Cutting gluten lowers tTG antibodies and can produce a falsely normal result, so do not start a gluten-free trial until after the blood draw.
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What this test is for
Tissue transglutaminase (tTG) antibodies are the autoantibodies the immune system produces in celiac disease, an autoimmune reaction to gluten that damages the small intestine. This panel measures both the IgA and IgG forms: tTG-IgA is the primary screening marker, while tTG-IgG matters because roughly 2 to 3 percent of people with celiac are IgA-deficient, in whom an IgA-only test can read falsely normal. Elevated antibodies point toward celiac disease and the symptoms it drives, including chronic diarrhea or constipation, bloating, abdominal pain, unexplained weight loss, iron-deficiency anemia, fatigue, and in children poor growth. A positive result is typically confirmed with a small-intestine biopsy, and the test only works if you have been eating gluten regularly, since a gluten-free diet lowers the antibodies and can mask the disease.
The separate single-antibody tests (tTG-IgA alone or tTG-IgG alone) each measure one form; this panel runs both together, which is the more complete screen and the right default when IgA status is unknown.
Biomarkers tested
Includes 2 biomarkers
- Specimen
- Serum
- Method
- Immunoassay
- Measures
- Concentration
- Specimen
- Serum
- Method
- Immunoassay
- Measures
- Concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 3 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
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Without membership
$0
pay as you go
At-cost pricing on labs, scans, and more
Priority turnaround on your results
On-demand clinician consults when you need guidance
Personalized action plans across supplements, exercise, nutrition, and sleep
AI health coaching to help you act on your results
Year-round medical support, with in-chat clinician escalation
All your health records in one personal vault, with trends and biological age tracking
Early access to new diagnostics and product releases
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a doctor's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate doctor visit before purchasing.
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