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Thorne

Methyl-Guard Plus

$62.99

Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult…

Size
90 capsules
Suggested use
Amount
1.00
Frequency
once per day
Format
Capsule

Directions

Take 1-3 capsules daily or as recommended by your health professional.

Delivery and returns

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3–6 business days
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1 business day

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Ingredient Information

Key Ingredients

Riboflavin (as Riboflavin 5’-Phosphate Sodium)Vitamin B6 (as Pyridoxal 5’-Phosphate)Vitamin B12 (as Methylcobalamin)Betaine Anhydrous (Trimethylglycine)

Ingredient Amounts

Serving Size:
Three Capsules
NameAmount
Riboflavin (as Riboflavin 5’-Phosphate Sodium)90 mg
Vitamin B6 (as Pyridoxal 5’-Phosphate)45 mg
Vitamin B12 (as Methylcobalamin)3 mg
Betaine Anhydrous (Trimethylglycine)1.8 g

Other Ingredients: Calcium (Citrate), Calcium Laurate, Hypromellose Capsule ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY If pregnant, consult your health professional before using this product. INTERACTIONS 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.

Methyl-Guard Plus Details

Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.

Thorne’s Methyl-Guard Plus features betaine (trimethylgycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.*

Benefits of Thorne’s Methyl-Guard Plus:

    • Nutritional support for individuals who have MTHFR gene mutations*
    • Enhanced cellular energy production fights fatigue*
    • Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health*
    • Promotes fat metabolism and lean body composition*
    • Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep*
    • Promotes liver detoxification of many substances, including hormones like estrogen*

Why is methylation important:

Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:

    • Cardiovascular health
    • Cellular energy production
    • Fat metabolism
    • Neurological function
    • DNA production
    • Liver detoxification processes
    • Eye health
    • Histamine balance

Who can benefit from Thorne's Methyl-Guard Plus:

    • Individuals with mutations to MTHFR and other genes that adversely affect methylation*
    • Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health*
    • Women seeking support for estrogen metabolism and bone health*
    • Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition*
    • Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables

Features of Thorne's Methyl-Guard Plus:

    • Betaine, also known as trimethylglycine, is a superior methyl donor
    • The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations*
    • Active forms of vitamins B2 and B6 – key cofactors in methylation processes
    • B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work*
    • Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard®

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