Sirolimus (Rapamune)
Tracks blood levels of an immunosuppressant to keep dosing effective without tipping into toxicity.
Consider this test if:
- Taking sirolimus after a kidney or other organ transplant and confirming you are in the target range
- Recently started sirolimus or had a dose change and need to recheck at steady state
- Monitoring for toxicity signs while on long-term immunosuppression
- Added or stopped another medication that could alter sirolimus levels
- HSA/FSA eligible
- Typical results in 2-4 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
Sirolimus is monitored as a trough level: the sample is usually drawn just before your next scheduled dose, not after it. Keep your dosing time consistent and tell the lab when you last took the drug. Fasting is not required. After a dose change, levels take several days to stabilize because of the long half-life, so timing the draw at steady state matters.
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What this test is for
Sirolimus (Rapamune) is an immunosuppressant used to prevent rejection after organ transplant, most often kidney. It has a narrow therapeutic window: too little raises rejection risk, too much causes toxicity, so blood levels are monitored to keep dosing in range. This test measures the concentration of sirolimus in whole blood, typically as a trough drawn just before the next dose. Because the drug's elimination half-life is roughly 60 to 72 hours, levels shift slowly, and testing is timed around dose changes and at steady intervals. Results are interpreted alongside your transplant team's target range, kidney function, and other immunosuppressants you take.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 2-4 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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