Mast Cell Nutrients

This product is a strong fit if:

• You experience recurring histamine-related symptoms (seasonal discomfort, skin flushing, GI reactivity, or environmental sensitivity) that seem linked to what you eat, where you are, or fluctuating life stressors.
• You've tried avoiding high-histamine foods but want to also support your body's ability to clear histamine effectively.
• You're looking for a comprehensive mast cell support formula rather than a single-ingredient approach.†

This product is a good fit if:

• You have confirmed or suspected DAO enzyme insufficiency and want to support histamine metabolism from multiple angles.
• You're interested in evidence-based botanical support for immune system and inflammatory response balance.
• You're already doing the basics (identifying triggers, supporting gut health) and want a targeted supplement layer.†

This product is probably NOT right for you if:

• You are looking primarily for a standalone glutathione supplement — the Emothion® dose here is supporting rather than therapeutic for glutathione repletion.
• You are seeking a single-ingredient quercetin product — this is a combination formula.
• You have a known COMT++ variant and are already taking high-dose quercetin — consult your provider before adding additional quercetin load.
• You have a known pineapple allergy (bromelain is derived from pineapple).
• You are pregnant or breastfeeding and have not consulted your provider.
• You are taking blood-thinning medications, as bromelain may potentiate anticoagulant effects — check with your provider.

Key Ingredients

• Quercefit® – A patented phytosome form of quercetin with clinically demonstrated superior absorption. Supports healthy mast cell function by supporting optimal IgE-mediated histamine release.†
• Luteolin Phospholipid SF – Luteolin complexed with phospholipids for enhanced bioavailability. Supports mast cell stability, modulates NF-κB signaling, and promotes histamine balance and neurological calm.†
• Bromelain – A proteolytic enzyme from pineapple standardized to 2400 GDU/g. Supports healthy inflammatory response, modulates immune cell activity, and may enhance absorption of other formula ingredients.†
• Stinging Nettle Extract – Urtica dioica root standardized to 0.8% sterols. Supports histamine comfort and healthy immune tone by supporting balance of key pro-inflammatory enzymes, including COX-1 and COX-2.†
• Emothion® S-Acetyl-Glutathione – An acetylated glutathione with superior oral stability. Supports the body's master antioxidant system and helps support the normal protection of mast cells from oxidative stress during activation events.†
• Vitamin C – As 99% pure ascorbic acid. Required cofactor for DAO, the primary histamine-degrading enzyme. Also supports mast cell membrane stability and regenerates quercetin to its active form.†