RPR (Diagnosis) with Reflex to Titer and Confirmatory Testing
The standard blood screen for syphilis, from recent exposure to long-standing infection.
Consider this test if:
- A painless sore, body rash (including palms or soles), or swollen lymph nodes that could point to syphilis
- A new or recent partner, or a sexual health check that includes syphilis
- Pregnant and completing recommended prenatal infection screening
- Confirming response after syphilis treatment, since titers are expected to fall
- A known exposure to a partner diagnosed with syphilis
- HSA/FSA eligible
- Results delivered to your dashboard · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Reflex testing
If your RPR is reactive, follow-up testing runs automatically: a titer to measure antibody levels and a treponemal-specific confirmatory antibody test to verify the result. Both are included at no additional cost.
Pre-test considerations
No fasting or special preparation is required, and timing during the day does not matter. Very recent exposure can produce a negative result before antibodies rise, so retesting may be needed if infection is still suspected.
Video consult with your Care Team
A 1:1 call to discuss your health.
What members say on Trustpilot
What this test is for
RPR (rapid plasma reagin) is a nontreponemal blood test used to screen for and help diagnose syphilis, the infection caused by Treponema pallidum. It detects reagin antibodies that rise during active infection, which is why it is the traditional starting point for both symptom-driven testing (a genital sore, rash on the palms or soles, swollen lymph nodes) and routine screening in pregnancy or higher-risk situations. A reactive RPR is not conclusive on its own: nontreponemal tests can be falsely positive with pregnancy, autoimmune disease, older age, and other infections, and can be falsely negative very early after exposure. That is why any reactive result is confirmed with a treponemal-specific antibody test before syphilis is diagnosed.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Fast, dashboard-delivered results
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
cancel anytime
Without membership
$0
pay as you go
At-cost pricing on labs, scans, and more
Priority turnaround on your results
On-demand clinician consults when you need guidance
Personalized action plans across supplements, exercise, nutrition, and sleep
AI health coaching to help you act on your results
Year-round medical support, with in-chat clinician escalation
All your health records in one personal vault, with trends and biological age tracking
Early access to new diagnostics and product releases
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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