Skip to main content
Build my panel
Pure Encapsulations

PMS Essentials

$68.99

Supports menstrual comfort and mood and helps lessen fatigue and cravings* ProSoothe II provides a comprehensive nutrient and botanical approach to support mood, cravings, cramps and bloating associated with the menstrual cycle. Calcium plays a role in healthy smooth muscle function and menstrual comfort. Vitamin D has…

Size
120 capsules
Suggested use
Amount
2.00
Frequency
once per day
Format
Capsule

Directions

As a dietary supplement, take 2 capsules, 1-2 times daily, with meals. May be used daily or during the luteal phase only, as directed by your health professional

Warnings and label notes
  • DimaCal™ is a registered trademark of Albion Laboratories, Inc. Malates covered by U.S. Patent 6, 706, 904.
  • Relora® is a registered trademark of InterHealth N.I. Relora
  • Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, particularly psychiatric medication, consult your health professional before use. Do not use concurrently with antidepressants. Rare reported side effects include GI upset, headache, itching, rash, insomnia, weight gain or irregular menstrual bleeding. Consult your physician for more information.
  • Chaste tree could alter the effectiveness of hormone replacement therapy or oral contraceptives. Because of dopaminergic actions, there is concern that chaste tree may interfere with dopaminergic agonists and dopamine antagonists. Calcium should be taken separately from certain antibiotics, bisphosphonates and thyroid medications. Consult your physician for more information.
Delivery and returns

Shipping choices at checkout

Standard
3–6 business days
Priority
1–3 business days
Next business day
1 business day

Standard shipping is free on supplement orders of $60 or more.

Standard shipping to Alaska, Hawaii, and Puerto Rico takes 10–13 business days. Next business day is not available there.

We will email tracking when your order ships.

Final sale

Orders cannot be cancelled or changed after checkout. For a damaged, wrong, missing, or undelivered item, email help@mitohealth.com within 14 days.

Ingredient Information

Key Ingredients

Vitamin E (as d-alpha tocopherol succinate)Vitamin B6 (as pyridoxal 5’ phosphate) (activated B6)Calcium (as DimaCal™ di-calcium malate)Magnesium (as di-magnesium malate)(Albion™)Chaste tree extract (vitex agnus-castus) (fruit)Relora®Rhodiola extract (Rhodiola rosea) (root) (standardized to contain 3% total rosavins and min. 1% salidroside)

Ingredient Amounts

Serving Size:
Two vegetarian capsules
NameAmount
Vitamin E (as d-alpha tocopherol succinate)134mg
Vitamin B6 (as pyridoxal 5’ phosphate) (activated B6)33mg
Calcium (as DimaCal™ di-calcium malate)100mg
Magnesium (as di-magnesium malate)(Albion™)100mg
Chaste tree extract (vitex agnus-castus) (fruit)200mg
Relora®270mg
Rhodiola extract (Rhodiola rosea) (root) (standardized to contain 3% total rosavins and min. 1% salidroside)50mg

Other Ingredients: vegetarian capsule (cellulose, water), modified food and corn starch, ascorbyl palmitate, silicon dioxide vegetarian capsule (cellulose, water), modified food and corn starch, ascorbyl palmitate, silicon dioxide

PMS Essentials Details

Supports menstrual comfort and mood and helps lessen fatigue and cravings*

ProSoothe II provides a comprehensive nutrient and botanical approach to support mood, cravings, cramps and bloating associated with the menstrual cycle. Calcium plays a role in healthy smooth muscle function and menstrual comfort. Vitamin D has similar effects, attributed to its ability to promote healthy calcium levels, cyclic hormone function and neurotransmitter activity. Healthy intracellular magnesium levels have been associated with maintaining positive mood during the luteal phase. Magnesium also plays an important role in nervous system sensitivity, providing support for muscle comfort, breast comfort and emotional well-being associated with the menstrual cycle.

Studies indicate the positive effect of vitamin B6 on premenstrual mood as well as its crucial role in enhancing the effect of magnesium. Vitamin E research suggests that it helps lessen breast tenderness as well as nervous tension and fatigue associated with the menstrual cycle. Traditionally used and clinically studied, chaste tree provides significant beneficial support for the hypothalamus and pituitary via its balancing effects. Relora® may help diminish stress-related sugary snack cravings and support emotional wellness while rhodiola supports energy and mental function.*

• Supports menstrual comfort and mood*
  • Helps lessen fatigue and cravings*
  • Made with hypoallergenic, vegan ingredients

More supplements to consider

Everything your health needs,
in one membership

  • A Mito member relaxing at home, checking their results on their phone

    Every test at our cost

    Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.

  • Mito dashboard on a tablet showing biomarker results and trends

    Continuous tracking, all in one place

    Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.

  • A Mito clinician checking in with a member over text messaging

    Year-round clinician support

    Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.

All for $9/month

Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.

Mito Membership

$9 /mo

cancel anytime

Without membership

$0

pay as you go

At-cost pricing on labs, scans, and more

Standard pricing

Supplements at member rates

On-demand clinician consults when you need guidance

$39 per 30 min
$99 per 30 min

Personalized action plans across supplements, exercise, nutrition, and sleep

AI health coaching to help you act on your results

Year-round medical support, with in-chat clinician escalation

All your health records in one personal vault, with trends and biological age tracking

Early access to new diagnostics and product releases

What members are saying

Excellent 4.8 out of 5
  • @nasdaily

  • 15/10 experience - I felt actually taken care of

    Super impressed with my Mito experience - the thoroughness of the intake, the data tracking and the doctor's visit.

    RS Reena Sudan
  • @ellarosemcfadin

  • Helped show an overall picture

    I would highly recommend this service to anyone that wants a more in-depth picture of their health and labs. The platform is super user friendly.

    BS Bo Sal
  • @katelyn_kim

  • Specific and actionable advice

    It felt like, for the first time, I had real data guiding me to make meaningful changes and I've definitely noticed the difference.

    MH Maya Hickey
  • @bryce_witmer

  • Tired of arguing with my PCP

    After extensive research, I decided Mito was the best option. The insights were clear and make sense. Mito gave me peace of mind and a path to follow.

    JO Josh
  • @alexandradawson

  • 3x the tests for less money

    A great alternative to the basic blood work at your local clinic. Love the report card format. Much better value.

    P Page
  • @daniklass

  • Best $9 a month I spend

    The action plan changes every time new results come in. I've actually never had a health company recommend doing less. Refreshing.

    DP Devi Patel
  • @natalieefer

  • Finally, prices that make sense

    Every test is published. I can see what it costs and what I save as a member. No surprises.

    KT Kenji Tanaka
  • @tyler_sarkisian

Frequently asked questions

View all FAQs
How does supplement pricing work?

Everyone sees the retail price and can buy at it, with no account needed. Mito members pay practitioner prices, and you can add the $9/month membership in your cart before you check out.

Where does the product information come from?

Brand, sizes, suggested use, and manufacturer copy are supplied through Fullscript. Mito guidance is labeled separately when it is available.

Where can I find Supplement Facts and warnings?

When the manufacturer includes them in the supplied product information, they appear above. We do not yet receive Supplement Facts or warnings as consistent, structured fields for every product.

Your privacy choices

We use cookies to run our site, understand usage, and support marketing. You can anytime.

Your cart

Check eligibility

Answer a few quick health questions so we can check this test is right for you before you book. It takes about a minute.

Checkout

Complete your order

Send this cart as a gift

Each checkout sends one gift to one recipient. To gift another person, complete a separate checkout, or buy for a whole team or group in one payment.

Who it’s for

We’ll email the gift to the recipient and price it for their state.

Included membership

Member pricing on every test, a personalised action plan, trend tracking, and Mito Concierge for these months. Never auto-renews.

Who it’s from

Your name appears in the gift email. We’ll send the receipt and redemption link to your email.

Email delivery

Set your location

Choose the state where you'll get tested to see the tests and labs available there.

Mito Concierge

Hello

I can build you a panel, explain what your biomarkers mean, and find the cheapest lab near you.

Loading sign in…