Prolactin, Total and Monomeric
Separates true high prolactin from inactive macroprolactin, so an elevated reading is not misread.
Consider this test if:
- Irregular, absent, or stopped periods, or trouble conceiving
- Low libido, erectile dysfunction, or unexpected breast milk production
- A previously high total prolactin that does not match how you feel
- Confirming whether elevated prolactin is active hormone or inactive macroprolactin before further imaging or treatment
- HSA/FSA eligible
- Results delivered to your dashboard · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
Prolactin rises with stress, exercise, eating, sleep, and nipple stimulation. Draw the sample in the morning, ideally 3 to 4 hours after waking, and sit quietly for 15 to 30 minutes beforehand. Avoid strenuous exercise and breast stimulation in the hours before the draw. Fasting is not required.
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What this test is for
Prolactin is a pituitary hormone that drives milk production and, when elevated, suppresses the reproductive axis. High prolactin causes irregular or absent periods, infertility, low libido, erectile dysfunction, unexpected breast milk production, and sometimes headaches or visual changes from a pituitary tumor. This test reports both total prolactin and monomeric prolactin, the small, biologically active form. That distinction matters because some people carry large amounts of macroprolactin, an inactive protein-bound form that inflates the total result without causing any symptoms, and PEG precipitation separates the two so a high total is not chased unnecessarily.
The routine Prolactin test reports total only and is the right first step for most people; this monomeric version is the one to use when total prolactin is elevated but symptoms do not fit, to confirm whether the active hormone is genuinely high. The Amenorrhea Panel adds LH and FSH for a broader workup of missed periods.
Biomarkers tested
Includes 2 biomarkers
- Specimen
- Serum or plasma
- Measures
- Mass concentration
Prolactin is made by the pituitary gland and its main job outside of pregnancy and lactation is to signal, so elevated levels suppress the reproductive hormones that drive libido, ovulation, and testosterone production. High prolactin shows up as irregular or missing periods, unexplained milk production, low libido, erectile dysfunction, or fertility difficulty, and can stem from certain medications, thyroid problems, stress, or a pituitary adenoma. If you're investigating a stalled cycle, unexplained galactorrhea, low libido, or working through a fertility workup with estradiol, FSH, and LH, prolactin tells you whether this hormone is the one crowding out the others.
- Specimen
- Serum or plasma
- Measures
- Mass concentration
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Fast, dashboard-delivered results
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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