Phosphorylated Tau 217 (p-tau217)
A blood marker that reflects the amyloid pathology underlying Alzheimer's disease.
Consider this test if:
- Progressive memory loss, word-finding trouble, or other cognitive changes being evaluated for a cause
- A family history of Alzheimer's disease and you want a less invasive look at amyloid status than imaging or a spinal tap
- Monitoring response while on an anti-amyloid therapy
- Sorting whether cognitive symptoms reflect Alzheimer's pathology versus another cause
- HSA/FSA eligible
- Typical results in 5-7 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No fasting is required. This is a specialized plasma test that must be collected in an EDTA tube, centrifuged, and frozen promptly, so it is run through a lab visit rather than a routine walk-in draw. Results are best interpreted alongside a cognitive assessment by a clinician.
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A 1:1 call to discuss your health.
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What this test is for
Phosphorylated tau 217 (p-tau217) is a form of the tau protein that rises in the blood as amyloid plaques accumulate in the brain, the hallmark pathology of Alzheimer's disease. It is one of the most accurate blood-based markers of amyloid pathology, tracking closely with amyloid PET imaging, and it offers a far less invasive alternative to spinal fluid testing or scans. Elevated p-tau217 supports a biological identification of Alzheimer's disease and is increasingly used to monitor people on newly approved anti-amyloid therapies. A result is most meaningful when paired with a clinical evaluation of memory and cognition, since the marker reflects underlying pathology rather than symptom severity. If the result is elevated, confirmatory imaging or cerebrospinal fluid testing and a specialist referral are the usual next steps.
- Specimen
- Serum or plasma
- Method
- Immunoassay
- Measures
- Mass concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 5-7 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
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Without membership
$0
pay as you go
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.
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