NAD+ (California Only)

NAD+ by Nutritional Frontiers is ideal for patients focused on energy restoration, metabolic efficiency, healthy aging, and neurological resilience. This formula is designed to complement protocols focused on mitochondrial support, detoxification, immune modulation, and metabolic repair.

NAD+ is a targeted formula designed to support mitochondrial function, healthy aging, and cellular metabolism through advanced nutrient delivery. This product combines 250 mg of ß-Nicotinamide Adenine Dinucleotide (NAD) with 250 mg of CurcuWIN®, a highly bioavailable turmeric extract standardized to curcuminoids. Together, these ingredients promote oxidative metabolism, support DNA repair mechanisms, modulate inflammatory signaling, and enhance cellular resilience to age-related stress. This synergistic formula is ideal for patients seeking metabolic restoration, cognitive support, or anti-aging interventions backed by emerging clinical science.

ß-Nicotinamide Adenine Dinucleotide (NAD)

-NAD is a coenzyme found in every living cell, critical for energy production, redox reactions, and cellular signaling.

-NAD functions as a cofactor in mitochondrial oxidative phosphorylation, directly influencing ATP generation and overall metabolic output.

-Research has demonstrated that NAD+ levels decline with age, impairing cellular repair and mitochondrial function. This decline is associated with metabolic diseases, neurodegenerative conditions, and immune dysregulation.

-Supplementation with NAD+ has been shown to activate sirtuins, a family of NAD-dependent enzymes involved in gene expression, DNA repair, and inflammation modulation.

-Studies in both animal and human models have shown that increasing NAD+ levels improves insulin sensitivity, enhances neurological performance, and supports longevity-related pathways.

CurcuWIN® Turmeric Rhizome Extract

-CurcuWIN® is a patented turmeric extract providing enhanced absorption and bioavailability of curcuminoids—up to 46 times more than standard curcumin.

-Turmeric’s curcuminoids have potent antioxidant and antiinflammatory effects, supporting a healthy cellular environment.

-Curcumin has been shown to enhance mitochondrial biogenesis, modulate NF-kB and COX-2 signaling, and protect cells against oxidative and inflammatory damage (Pan et al., Biochem Pharmacol, 2012).

-When combined with NAD+, curcuminoids may help preserve NAD+ levels and reduce inflammatory degradation, offering synergistic benefits for cellular longevity and metabolic health.

-CurcuWIN® delivers curcuminoids in a water-dispersible format that allows for greater tissue uptake and sustained systemic activity, making it ideal for clinical applications.