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Myositis Antibody Panel (MyoMarker 3 Plus)
Blood test

Myositis Antibody Panel (MyoMarker 3 Plus)

$2030.74 Member price $2843.04 Non-member
Excellent 4.8 out of 5

A broad autoantibody panel for diagnosing and subtyping inflammatory muscle disease.

Consider this test if:

  • Unexplained muscle weakness, especially in the hips, shoulders, or neck
  • A characteristic rash plus muscle symptoms suggesting dermatomyositis
  • Interstitial lung disease or unexplained breathlessness with joint pain or muscle involvement
  • HSA/FSA eligible
  • Typical results in 2-3 weeks · Reviewed by a real clinician
  • Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations

No fasting required and timing does not affect the result. This is a specialized antibody panel ordered during a workup for inflammatory muscle disease, so it is most useful alongside muscle enzymes and clinical findings rather than on its own.

Video consult with your Care Team

A 1:1 call to discuss your health.

$39.00 $99.00 Non-member

What members say on Trustpilot

  • “Mito gives me 3x the tests for less money” · Page
  • “15/10 experience - I felt actually taken care of” · Reena Sudan
  • “Deeper insights than a typical annual physical” · Nicki H
  • “Loved how specific and actionable the advice was” · Maya Hickey
  • “Stunned at how thorough both the testing and analysis was” · Mark
  • “Tired of arguing with my PCP. Mito got me the answers I was looking for.” · Josh
  • “So easy, it feels like a deluxe experience for your health” · Menetreto
  • “Excellent responsive customer service (a real rarity these days!)” · SS

What this test is for

This panel measures a wide set of myositis-specific and myositis-associated autoantibodies in serum, including the antisynthetase antibodies (Jo-1, PL-7, PL-12, OJ, EJ), Mi-2, SRP, TIF1-gamma, MDA5, and overlap markers such as Ku, PM/Scl-100, and U1/U2/U3 RNP. These antibodies help diagnose and characterize dermatomyositis, polymyositis, and antisynthetase syndrome, which present with muscle weakness, skin rash, interstitial lung disease, joint pain, and sometimes difficulty swallowing. Beyond confirming an autoimmune myopathy, the specific antibody found carries prognostic and subtype information: anti-MDA5 flags risk of rapidly progressive lung disease, anti-TIF1-gamma associates with cancer-related dermatomyositis, and the antisynthetase antibodies cluster with lung and joint involvement. If your question is narrowly whether anti-Jo-1 is present, the standalone Jo-1 antibody test answers that directly; this panel is for the broader workup when the antibody type is still unknown. Results are interpreted alongside muscle enzymes, EMG, imaging, and clinical findings, since a positive antibody defines the subset rather than standing alone.

Biomarkers tested

Includes 17 biomarkers

Mito dashboard showing biological age, health categories, biomarkers, and health trends

What you'll learn

  • Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.

  • Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.

  • Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.

  • Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.

What to expect

  1. 1 Book instantly

    Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.

  2. 2 Quick lab visit

    Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.

  3. 3 Typical results in 2-3 weeks

    Your results post straight to your dashboard as soon as the lab completes them.

  4. 4 Expert guidance

    Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.

Find a lab near you

Every draw site is a CLIA/CAP-accredited partner lab. Enter your ZIP to see the nearest locations.

    Everything your health needs,
    in one membership

    • A Mito member relaxing at home, checking their results on their phone

      Every test at our cost

      Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.

    • Mito dashboard on a tablet showing biomarker results and trends

      Continuous tracking, all in one place

      Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.

    • A Mito clinician checking in with a member over text messaging

      Year-round clinician support

      Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.

    All for $9/month

    Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.

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    $9 /mo

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    Without membership

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    On-demand clinician consults when you need guidance

    $39 per 30 min
    $99 per 30 min

    Personalized action plans across supplements, exercise, nutrition, and sleep

    AI health coaching to help you act on your results

    Year-round medical support, with in-chat clinician escalation

    All your health records in one personal vault, with trends and biological age tracking

    Early access to new diagnostics and product releases

    Learn more about Membership

    Frequently asked questions

    View all FAQs
    How does pricing work?

    Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.

    Where do I get tested?

    Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.

    Is this eligible for HSA/FSA?

    Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.

    When will I get my results?

    Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.

    Do I need a physician's order?

    No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.

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