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Mononucleosis Screen (Mono)
Blood test

Mononucleosis Screen (Mono)

Excellent 4.8 out of 5

Detects the antibody response that confirms mono behind a stubborn sore throat and weeks of fatigue.

Consider this test if:

  • Sore throat, swollen glands, and fever that are not improving as expected
  • Unusual fatigue and body aches lasting more than a week or two
  • A strep test came back negative but symptoms persist

Currently unavailable in your state.

This test isn't offered by labs in your state yet.

Pre-test considerations

No fasting required and timing during the day does not matter. The main timing factor is illness stage: heterophile antibodies can take one to two weeks to develop, so testing very early may give a falsely negative result. If symptoms continue after a negative test, a repeat or EBV-specific antibody testing may be needed.

Video consult with your Care Team

A 1:1 call to discuss your health.

$39.00 $99.00 Non-member

What members say on Trustpilot

  • “Mito gives me 3x the tests for less money” · Page
  • “15/10 experience - I felt actually taken care of” · Reena Sudan
  • “Deeper insights than a typical annual physical” · Nicki H
  • “Loved how specific and actionable the advice was” · Maya Hickey
  • “Stunned at how thorough both the testing and analysis was” · Mark
  • “Tired of arguing with my PCP. Mito got me the answers I was looking for.” · Josh
  • “So easy, it feels like a deluxe experience for your health” · Menetreto
  • “Excellent responsive customer service (a real rarity these days!)” · SS

What this test is for

The mononucleosis screen looks for heterophile antibodies, the immune response the body produces during an active Epstein-Barr virus infection. Mono typically causes sore throat, swollen lymph nodes, fever, and the deep, lingering fatigue that can last weeks. A positive result supports a mono diagnosis when symptoms fit, which helps distinguish it from strep throat and other causes of sore throat. The heterophile antibody can take a week or more to appear, so a negative result early in the illness does not rule mono out and may warrant a repeat test or EBV-specific antibody testing. It is most useful in the first weeks of symptoms, since the antibody fades over time and the test is not meant to confirm a past infection.

Specimen
Serum
Measures
Presence / threshold
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What you'll learn

  • Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.

  • Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.

  • Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.

  • Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.

What to expect

  1. 1 Book instantly

    Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.

  2. 2 Quick lab visit

    Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.

  3. 3 Typical results in 1-2 days

    Your results post straight to your dashboard as soon as the lab completes them.

  4. 4 Expert guidance

    Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.

Find a lab near you

Every draw site is a CLIA/CAP-accredited partner lab. Enter your ZIP to see the nearest locations.

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    in one membership

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      Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.

    • Mito dashboard on a tablet showing biomarker results and trends

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      Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.

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      Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.

    All for $9/month

    Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.

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    Frequently asked questions

    View all FAQs
    How does pricing work?

    Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.

    Where do I get tested?

    Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.

    Is this eligible for HSA/FSA?

    Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.

    When will I get my results?

    Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.

    Do I need a doctor's order?

    No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate doctor visit before purchasing.

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