Lyme Disease Ab with Reflex to Blot (IgG, IgM)
First-step antibody screen for tick-borne Borrelia infection, with automatic confirmation built in.
Consider this test if:
- A known tick bite or an expanding bullseye (erythema migrans) rash
- Fever, fatigue, headache, joint pain, or muscle aches after time outdoors in a tick-endemic area
- Unexplained joint swelling, facial droop, or neurological symptoms following possible exposure
- Recent travel or activity in wooded or grassy regions where Lyme is common
- HSA/FSA eligible
- Results delivered to your dashboard · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Reflex testing
If your antibody screen comes back positive or equivocal, a confirmatory immunoblot (Western blot) test runs automatically to verify the result with high specificity. This follow-up is done at no additional cost.
Pre-test considerations
No fasting required and timing during the day does not matter. Because antibodies can take two to six weeks to appear after infection, testing too early may miss an active case; if suspicion is high and the first result is negative, retesting after a few weeks is often warranted.
Video consult with your Care Team
A 1:1 call to discuss your health.
What members say on Trustpilot
What this test is for
This test detects antibodies to Borrelia burgdorferi, the bacterium that causes Lyme disease and is transmitted through the bite of infected ticks. It is the high-sensitivity first step in the CDC's two-tier testing algorithm, designed to catch as many true infections as possible before a more specific confirmatory test is run. It is commonly ordered when someone has a known tick bite, an expanding bullseye rash, or symptoms like fever, fatigue, headache, joint pain, and muscle aches after possible exposure. Antibodies take a few weeks to develop, so testing very early in infection can produce a false negative, and a positive screen reflects immune response rather than a confirmed active infection until the reflex blot supports it.
- Specimen
- Serum
- Method
- Immunoassay
- Measures
- Concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Fast, dashboard-delivered results
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
cancel anytime
Without membership
$0
pay as you go
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On-demand clinician consults when you need guidance
Personalized action plans across supplements, exercise, nutrition, and sleep
AI health coaching to help you act on your results
Year-round medical support, with in-chat clinician escalation
All your health records in one personal vault, with trends and biological age tracking
Early access to new diagnostics and product releases
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.
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