Interleukin-10 (IL-10)
An anti-inflammatory cytokine that rises in immune suppression and severe hyperinflammation alike.
Consider this test if:
- Investigating a suspected hyperinflammation syndrome such as HLH, macrophage activation syndrome, or cytokine release syndrome
- Monitoring cytokine activity in severe infection or sepsis where prognosis is in question
- Characterizing the immune profile alongside other cytokines in asthma, chronic urticaria, or rheumatoid arthritis
- Tracking immune response during allergen immunotherapy
- HSA/FSA eligible
- Typical results in 4-7 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No fasting is required. Cytokine levels shift with acute infection, inflammation, and the timing of an immune stimulus, so note any active illness or recent immunotherapy when interpreting the result. Grossly hemolyzed or lipemic samples are not suitable for testing.
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What this test is for
Interleukin-10 (IL-10) is an anti-inflammatory cytokine that dampens the immune response by inhibiting TH1 cells, NK cells, and macrophages involved in pathogen clearance. It plays a central role in immune tolerance, including the immune suppression seen during allergen immunotherapy. Elevated IL-10 is a common and clinically important finding in hyperinflammation syndromes such as hemophagocytic lymphohistiocytosis (HLH), macrophage activation syndrome, sepsis, cytokine release syndrome, and severe COVID-19, where markedly high levels can signal an unfavorable prognosis. It has also been studied in asthma control, chronic spontaneous urticaria, and rheumatoid arthritis. This is a specialized cytokine test ordered for specific immune questions, distinct from the pro-inflammatory cytokines IL-1 beta, IL-4, and IL-6, which are measured separately to characterize different arms of the inflammatory response.
- Specimen
- Serum or plasma
- Measures
- Mass concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 4-7 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
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Without membership
$0
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.
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