Insulin Autoantibody (IAA)
An early islet autoantibody that helps separate type 1 diabetes from type 2 and other forms.
Consider this test if:
- A first-degree relative has type 1 diabetes or you carry a high-risk HLA genotype
- New or atypical diabetes where it is unclear whether it is type 1, type 2, or LADA
- A child or young adult with new hyperglycemia and possible autoimmune diabetes
- Clarifying whether insulin treatment is likely to be needed in someone not yet on insulin
- Building a fuller islet-autoantibody picture alongside GAD65, ZnT8, and IA-2
- HSA/FSA eligible
- Results delivered to your dashboard · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No fasting required. This test should be done before starting insulin therapy: once insulin injections begin, the body produces antibodies to injected insulin that this assay cannot distinguish from autoimmune ones, making the result uninformative.
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What this test is for
Insulin autoantibodies (IAA) are antibodies the immune system makes against its own insulin, and they are one of four islet autoantibodies that mark the autoimmune process behind type 1 diabetes (T1D). A positive result points to autoimmune beta-cell destruction and helps distinguish T1D from type 2 diabetes and from latent autoimmune diabetes in adults (LADA), a distinction that is misclassified in roughly 40% of adults presenting with new T1D. IAA is usually the first autoantibody to appear in young children and becomes less common with age, which makes it most informative early. It is not useful once insulin treatment has started, because injected insulin itself triggers antibodies that the test cannot tell apart from autoimmune ones. Because diagnosing presymptomatic T1D requires at least two positive islet autoantibodies, IAA is interpreted alongside GAD65, ZnT8, and IA-2 rather than on its own.
- Specimen
- Serum
- Method
- Radioimmunoassay
- Measures
- Concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Fast, dashboard-delivered results
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
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Without membership
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.
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