Glucose-6-Phosphate Dehydrogenase (G6PD)
The most common enzyme deficiency worldwide, and a key check before certain drugs and foods can trigger hemolysis.
Consider this test if:
- You have African, Mediterranean, or Asian ancestry, or a family history of G6PD deficiency
- Episodes of jaundice, dark urine, fatigue, or anemia following infection, fava beans, or a new medication
- About to start an antimalarial, certain sulfa drugs, or another oxidative medication
- Confirming status before traveling to a malaria region
- Investigating prolonged or pronounced neonatal jaundice
- HSA/FSA eligible
- Results delivered to your dashboard · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No fasting required. Timing matters: if blood is drawn during or just after an acute hemolytic episode, enzyme activity can appear falsely normal because young red cells have higher G6PD activity, so retest after recovery if deficiency is still suspected.
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What this test is for
Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme that protects red blood cells from oxidative damage. This test measures G6PD enzyme activity in red blood cells; a low value indicates G6PD deficiency, an X-linked condition that affects males more than females and is most common in people of African, Mediterranean, or Asian descent. People with deficiency can have episodes of acute hemolytic anemia (jaundice, fatigue, dark urine, an enlarged spleen) triggered by infections, fava beans, and certain drugs such as some sulfonamides and antimalarials, so knowing your status guides what to avoid. Note that activity can read falsely normal if blood is drawn just after a hemolytic episode, because young reticulocytes carry higher G6PD activity; if deficiency is suspected, repeat the test once recovered. Molecular genetic testing is the better tool when a heterozygous female may have normal enzyme activity despite carrying the variant.
- Specimen
- Red blood cells
- Measures
- Count
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Fast, dashboard-delivered results
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.
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