Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) Panel
The two pituitary hormones that drive ovulation, sperm production, and the reproductive timeline.
Consider this test if:
- Irregular, absent, or changing menstrual cycles, or symptoms of perimenopause
- Investigating trouble conceiving in either partner
- Low libido, fatigue, or low testosterone symptoms in men, to separate testicular from pituitary causes
- Symptoms of PCOS such as irregular cycles, acne, or unwanted hair growth
- Confirming menopausal status or evaluating early ovarian decline
- HSA/FSA eligible
- Typical results in 1-2 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
In menstruating women, timing matters: these are usually drawn on cycle days 2 to 4 unless your clinician specifies otherwise, since levels shift across the cycle and spike at ovulation. Hormonal contraceptives and hormone therapy alter results, so note what you take. No fasting required.
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What this test is for
FSH and LH are released by the pituitary gland to direct the ovaries and testes, and measuring them together shows whether a reproductive problem starts in the gonads or in the brain's signaling above them. In women, high FSH and LH point toward menopause or primary ovarian insufficiency, while a high LH relative to FSH is a classic pattern in polycystic ovary syndrome. In men, high levels suggest the testes are failing to respond (primary hypogonadism), while low levels suggest the pituitary or hypothalamus is not sending the signal (secondary hypogonadism). The pairing matters because the ratio and direction together separate causes that a single hormone cannot.
This panel measures both gonadotropins. If you also want estradiol to interpret ovarian status, the LH, FSH, and Estradiol panel adds it; if irregular or absent periods are the question, the Amenorrhea panel adds prolactin.
Biomarkers tested
Includes 2 biomarkers
FSH is the pituitary signal that drives egg maturation in the ovaries and sperm production in the testes. In women, rising FSH reflects declining ovarian reserve, making it central to fertility planning, cycle irregularity workups, and confirming perimenopause or menopause. In men, elevated FSH points to impaired sperm production, while low levels in either sex suggest the pituitary or hypothalamus isn't sending the signal at all, useful context alongside LH and estradiol.
- Specimen
- Serum or plasma
- Measures
- Concentration
LH is the pituitary signal that triggers ovulation in women and drives testosterone production in the testes of men, acting as the messenger between brain and gonads. In women, tracking LH alongside FSH and estradiol clarifies where you are in your cycle, confirms ovulation timing for fertility planning, and helps investigate irregular periods or suspected PCOS. In men, a low LH with low testosterone points to a signaling problem upstream in the pituitary, while a high LH with low testosterone points to testicular failure, a distinction that changes how low libido, fatigue, or muscle loss get treated.
- Specimen
- Serum or plasma
- Measures
- Concentration
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 1-2 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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