Creatinine Clearance
A measured look at how well your kidneys filter, using a full 24-hour urine collection.
Consider this test if:
- Following up an abnormal or borderline eGFR with a measured filtration rate
- Monitoring known kidney impairment or a condition like diabetes or hypertension that affects the kidneys
- Estimating kidney function before or during treatment with medications that are dose-adjusted for renal function
- Very high or very low muscle mass, where the blood-only eGFR estimate is less reliable
- HSA/FSA eligible
- Results delivered to your dashboard · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
The test combines a blood draw with a complete 24-hour urine collection, so accuracy depends on collecting every void during the window and recording the exact start and stop times. Missing even one sample lowers the result artificially. No preservative is needed; keep the collection cool. Heavy cooked-meat intake and intense exercise can transiently raise creatinine, so keep activity and diet typical during collection.
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What this test is for
Creatinine clearance estimates glomerular filtration rate (GFR) by comparing creatinine in your blood with the creatinine your kidneys excrete into urine over a full 24 hours. Because muscle produces creatinine at a fairly steady rate, the volume of plasma your kidneys clear of it per minute is a direct measure of filtering capacity. A low clearance points to reduced kidney function and is used to evaluate chronic kidney disease, monitor known kidney impairment, and adjust medication dosing in people with declining function.
This is the timed-collection, measured version. The simpler blood-only Creatinine with eGFR test estimates filtration from a single serum sample and is the right default for routine screening; creatinine clearance is worth the 24-hour collection when a more precise filtration measure is needed, such as at the extremes of muscle mass or to confirm an equivocal eGFR.
Biomarkers tested
Includes 8 biomarkers
- Specimen
- Urine
- Measures
- Volume
- Method
- Patient-reported
- Measures
- Mass
Creatinine is a waste product released as your muscles break down creatine for energy, and your kidneys filter it out of the blood at a steady rate. When creatinine rises, it usually means the kidneys are filtering less efficiently, making it the core marker for kidney function and the basis for calculating eGFR. Test it as a baseline for kidney health, to monitor the impact of blood pressure, diabetes, high-protein diets, or supplements like creatine, or to investigate unexplained fatigue, swelling, or changes in urination.
- Specimen
- Serum or plasma
- Measures
- Mass concentration
- Specimen
- Urine and serum/plasma
- Measures
- Ratio
- Specimen
- Urine
- Measures
- Ratio
- Specimen
- Serum, plasma, or blood
- Method
- Creatinine-based (CKD-EPI)
- Measures
- Ratio
- Method
- Patient-reported
- Measures
- Length
- Specimen
- Urine
- Measures
- Time
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Fast, dashboard-delivered results
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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