Copeptin
A stable stand-in for antidiuretic hormone, used to sort out the cause of excessive thirst and urination.
Consider this test if:
- Persistent excessive thirst and urinating large volumes day and night
- Working up suspected diabetes insipidus versus primary polydipsia
- A clinician has ordered a hypertonic saline or arginine stimulation test
- Tracking water-balance disorders alongside sodium and osmolality
- HSA/FSA eligible
- Typical results in 3-5 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No specific fasting is generally required for a baseline draw, but stimulation-test protocols (hypertonic saline or arginine) have their own preparation and timing instructions that your clinician will provide. Acute stress, recent illness, and large swings in hydration can move the result, so collection conditions matter.
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What this test is for
Copeptin is released in equal amounts with arginine vasopressin (ADH), the hormone that controls water retention and thirst, but it is far more stable in the blood, which makes it a reliable surrogate for ADH that an actual ADH assay struggles to measure. High copeptin reflects strong vasopressin output and points toward nephrogenic diabetes insipidus or primary polydipsia, while low copeptin suggests the body is not producing enough ADH (central diabetes insipidus). It is the key marker when evaluating polyuria and polydipsia, the cluster of excessive urination, constant thirst, and high fluid intake that needs sorting into a hormonal versus kidney cause. A single baseline level often separates these conditions, and copeptin is also measured during hypertonic saline or arginine stimulation tests when the baseline is equivocal. Because it tracks blood volume and osmolality, it can also rise with acute physiologic stress, so the result is read against the clinical picture.
- Specimen
- Serum or plasma
- Method
- Immunoassay
- Measures
- Substance concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 3-5 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.
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