Copeptin
A stable stand-in for antidiuretic hormone, used to sort out the cause of excessive thirst and urination.
Consider this test if:
- Persistent excessive thirst and urinating large volumes day and night
- Working up suspected diabetes insipidus versus primary polydipsia
- A clinician has ordered a hypertonic saline or arginine stimulation test
- Tracking water-balance disorders alongside sodium and osmolality
- HSA/FSA eligible
- Typical results in 3-5 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No specific fasting is generally required for a baseline draw, but stimulation-test protocols (hypertonic saline or arginine) have their own preparation and timing instructions that your clinician will provide. Acute stress, recent illness, and large swings in hydration can move the result, so collection conditions matter.
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What this test is for
Copeptin is released in equal amounts with arginine vasopressin (ADH), the hormone that controls water retention and thirst, but it is far more stable in the blood, which makes it a reliable surrogate for ADH that an actual ADH assay struggles to measure. High copeptin reflects strong vasopressin output and points toward nephrogenic diabetes insipidus or primary polydipsia, while low copeptin suggests the body is not producing enough ADH (central diabetes insipidus). It is the key marker when evaluating polyuria and polydipsia, the cluster of excessive urination, constant thirst, and high fluid intake that needs sorting into a hormonal versus kidney cause. A single baseline level often separates these conditions, and copeptin is also measured during hypertonic saline or arginine stimulation tests when the baseline is equivocal. Because it tracks blood volume and osmolality, it can also rise with acute physiologic stress, so the result is read against the clinical picture.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 3-5 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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