Complement C3a desArg Fragment
A breakdown product that reflects how strongly the complement system has been activated.
Consider this test if:
- Evaluating suspected complement-mediated inflammatory or autoimmune disease
- Investigating unexplained vasculitis, kidney inflammation, or systemic inflammatory activity
- Working up a condition where the degree of complement activation guides management
- Tracking complement activity over time alongside C3 and C4 levels
- HSA/FSA eligible
- Typical results in 4-7 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
This is a blood draw with strict handling: the sample is collected into a chilled EDTA tube, mixed with a preservative, separated, and frozen immediately, so it is done at a lab equipped for the special kit. Do not have any radioactive isotopes administered within 48 hours before the draw, as they interfere with the assay. Fasting is not required.
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What this test is for
C3a is an anaphylatoxin released when the complement cascade, a front-line part of the innate immune system, is activated. The assay measures C3a together with its stable C3a-desArg fragment, which lingers in circulation and reflects the recent extent of complement activation. Elevated levels indicate excessive complement activity, which contributes to the pathogenesis of many acute and chronic inflammatory conditions, including autoimmune disease, vasculitis, certain kidney diseases, and systemic inflammatory states. This is a specialized research-and-evaluation marker, not a routine inflammation screen, so it is interpreted alongside the specific clinical question and other complement components such as C3 and C4. It requires careful chilled, preserved, frozen handling, so it is ordered when complement-driven inflammation is genuinely in question rather than as a general checkup.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 4-7 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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