Calprotectin, Fecal
A stool marker of intestinal inflammation that helps separate IBD from IBS.
Consider this test if:
- Persistent diarrhea, abdominal pain, or blood in stool with no clear cause
- Trying to tell inflammatory bowel disease apart from IBS before committing to endoscopy
- Diagnosed with Crohn's or ulcerative colitis and tracking inflammation between visits
- Checking whether a flare is settling or a treatment is working
- Unexplained weight loss or persistent change in bowel habits
- HSA/FSA eligible
- Typical results in 4-5 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No fasting required. Collect a random stool sample in the provided clean container; do not contaminate it with urine or toilet water, and do not use stool that has touched diaper material. Keep the sample refrigerated or frozen and return it promptly, since refrigerated or thawed samples received more than three days after collection are rejected. NSAIDs can raise calprotectin by irritating the gut lining, so note recent use.
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What this test is for
Fecal calprotectin is a protein released by white blood cells (neutrophils) when they migrate into the gut lining in response to inflammation. Its concentration in stool tracks the degree of intestinal inflammation, which is why it is one of the most useful non-invasive markers for inflammatory bowel disease, including Crohn's disease and ulcerative colitis. A high result points to organic inflammation in the bowel, often many times the normal level, and usually leads to endoscopy and biopsy; a low result makes IBD unlikely and supports a functional diagnosis like irritable bowel syndrome. It is most useful for distinguishing IBD from IBS in people with persistent diarrhea, abdominal pain, or change in bowel habits, since symptoms alone rarely separate the two. It is also used to monitor known IBD, where a falling level reflects mucosal healing and a rising level can signal a flare before symptoms return.
- Specimen
- Stool
- Measures
- Count
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 4-5 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
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Without membership
$0
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.
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