Antinuclear Antibody (ANA)
Specific autoantibodies that help pinpoint lupus, Sjögren's, and related connective tissue disease.
Consider this test if:
- Joint pain, fatigue, facial rash, or photosensitivity that suggests lupus
- Dry eyes and dry mouth, with or without joint symptoms, raising the question of Sjögren's
- A positive ANA screen that needs to be characterized by specific antibody target
- Known autoimmune disease where dsDNA is being followed to gauge activity
- A family history of lupus or connective tissue disease alongside suggestive symptoms
Currently unavailable in your state.
This test isn't offered by labs in your state yet.
Pre-test considerations
No fasting required and no special timing. This is a standard blood draw, and results are not affected by meals or time of day.
Video consult with your Care Team
A 1:1 call to discuss your health.
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What this test is for
This panel measures specific antinuclear antibodies (Smith, RNP, double-stranded DNA, SS-A 52, SS-A 60, and SS-B) that are linked to particular autoimmune diseases. Double-stranded DNA and Smith antibodies are highly specific for systemic lupus erythematosus, SS-A and SS-B point toward Sjögren's syndrome, and RNP is associated with mixed connective tissue disease. These antibodies attack the body's own cell nuclei and help explain symptom clusters like joint pain, fatigue, photosensitive rashes, dry eyes and mouth, and Raynaud's.
This is the antibody-characterization step, not the initial screen: the related ANA-by-IFA tests detect whether any antinuclear antibody is present, while this panel identifies which specific targets are driving the response, which narrows the diagnosis. dsDNA in particular tends to rise and fall with lupus disease activity, so it is also useful for tracking over time.
Biomarkers tested
Includes 6 biomarkers
- Specimen
- Serum
- Measures
- Concentration
- Specimen
- Serum
- Method
- Immunoassay
- Measures
- Concentration
- Specimen
- Serum
- Measures
- Concentration
- Specimen
- Serum
- Method
- Immunoassay
- Measures
- Presence / threshold
- Specimen
- Serum
- Measures
- Concentration
- Specimen
- Serum
- Method
- Immunoassay
- Measures
- Concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 2-3 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
cancel anytime
Without membership
$0
pay as you go
At-cost pricing on labs, scans, and more
Priority turnaround on your results
On-demand clinician consults when you need guidance
Personalized action plans across supplements, exercise, nutrition, and sleep
AI health coaching to help you act on your results
Year-round medical support, with in-chat clinician escalation
All your health records in one personal vault, with trends and biological age tracking
Early access to new diagnostics and product releases
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a doctor's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate doctor visit before purchasing.
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