Anti-IgE Antibody (IgG)
An autoantibody linked to autoimmune chronic hives that standard allergy testing does not capture.
Consider this test if:
- Hives and itching that have recurred for more than six weeks with no identifiable trigger
- Chronic urticaria that has not responded well to standard antihistamines
- Working up whether long-standing hives have an autoimmune cause
- Allergy testing has come back negative but symptoms persist
- HSA/FSA eligible
- Results delivered to your dashboard · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No fasting required and no specific timing needed. This is a single blood draw.
Video consult with your Care Team
A 1:1 call to discuss your health.
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What this test is for
This test measures IgG autoantibodies directed against your own IgE, one of the immune mechanisms behind autoimmune chronic urticaria. Chronic urticaria, recurring hives with redness and itching lasting more than six weeks, affects roughly 1 to 6% of people, and in a subset the cause is autoimmune: antibodies bind IgE or its high-affinity receptor and trigger mast cells and basophils to release histamine. Anti-IgE autoantibodies are found in about 5 to 10% of chronic urticaria cases, while the related anti-receptor antibody accounts for another 30 to 40%, so a positive result here helps confirm an autoimmune driver rather than an external allergen. It is a diagnostic and management aid for chronic hives that have no clear trigger, not a test for food or environmental allergy. If your hives track with a specific exposure, allergen-specific IgE testing is the more relevant route.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Fast, dashboard-delivered results
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
cancel anytime
Without membership
$0
pay as you go
At-cost pricing on labs, scans, and more
Priority turnaround on your results
On-demand clinician consults when you need guidance
Personalized action plans across supplements, exercise, nutrition, and sleep
AI health coaching to help you act on your results
Year-round medical support, with in-chat clinician escalation
All your health records in one personal vault, with trends and biological age tracking
Early access to new diagnostics and product releases
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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