Anemia Panel
A full workup for why you're anemic, separating iron, B12, folate, and red-cell causes in one draw.
Consider this test if:
- Unexplained fatigue, weakness, shortness of breath, or poor exercise recovery
- A prior CBC showed anemia or abnormal red-cell size without a clear cause
- Heavy periods, a vegetarian or vegan diet, or GI conditions that limit absorption
- You want to know whether anemia is driven by iron, B12, folate, or marrow output
- Tracking recovery after starting iron, B12, or folate replacement
- HSA/FSA eligible
- Typical results in 1 day · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
Draw in the morning after an overnight fast when possible, since serum iron and iron saturation fluctuate through the day and rise after meals and iron supplements. Hold iron-containing supplements for about 24 hours before the draw for a cleaner iron and ferritin reading. Note any B12 or folate supplements, since they raise those results. Ferritin also rises with infection or inflammation, which can mask low iron stores.
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What this test is for
This panel combines a complete blood count with differential, reticulocytes, full iron studies (iron, TIBC, UIBC, saturation, ferritin), vitamin B12, and folate to find the cause of anemia rather than just confirm it. The CBC shows whether red cells are too few, too small, or too large, and reticulocytes show whether the marrow is responding; the iron, B12, and folate markers then point to the most common nutritional drivers. Small red cells with low ferritin and low iron saturation point to iron deficiency, while large red cells with low B12 or folate point to a different mechanism entirely. It is commonly ordered to investigate fatigue, weakness, shortness of breath, pale skin, hair loss, or poor exercise tolerance, especially when a basic CBC is abnormal but the reason is unclear. If you only need to recheck one piece, such as ferritin after starting iron, the standalone marker is cheaper than repeating the whole panel.
Biomarkers tested
Includes 28 biomarkers
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number concentration
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number fraction (%)
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number concentration
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number fraction (%)
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Distribution width
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number concentration
Ferritin stores iron inside cells and reveals how much iron your body has banked for making red blood cells, energy, and thyroid hormone. Low ferritin is usually the earliest sign of depleting iron reserves, often showing up as fatigue, hair shedding, poor exercise tolerance, or brain fog well before anemia appears on a standard blood count. High ferritin can reflect iron overload, but it also rises with inflammation, heavy alcohol use, or liver stress, so it doubles as a useful baseline for athletes tracking recovery and a first clue when something else is inflaming the system.
- Specimen
- Serum or plasma
- Measures
- Mass concentration
Folate fuels the one-carbon reactions that build DNA and recycle homocysteine, work that shows up fastest in cells that divide quickly, like red blood cells. Low folate produces the same picture as B12 deficiency: fatigue, weakness, poor concentration, irritability, and large, immature red blood cells (macrocytic anemia), so the two are usually tested together to sort out which one is driving symptoms. It's also relevant during preconception and pregnancy planning, since adequate folate is what prevents neural tube defects, and worth checking if you drink heavily, follow a restrictive diet, or take medications that interfere with folate metabolism.
- Specimen
- Serum or plasma
- Measures
- Mass concentration
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number fraction (%)
Hematocrit measures the percentage of your blood volume made up of red blood cells, the cells that carry oxygen from your lungs to every tissue. Low hematocrit points to anemia and pairs with fatigue, breathlessness, dizziness, or poor exercise tolerance, while high hematocrit can reflect dehydration, high altitude, smoking, or overactive red cell production, and thickens blood in ways that matter for cardiovascular risk. It's a core piece of the complete blood count, useful as a baseline read on oxygen-carrying capacity and for tracking how iron status, training, or altitude exposure are shifting your blood over time.
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Volume fraction (%)
- Specimen
- Whole blood
- Measures
- Mass concentration
Immature granulocytes are neutrophil precursors that your bone marrow releases early when it's scrambling to meet demand, cells that normally stay put until fully mature. A raised count signals active infection, inflammation, or marrow stress before other markers catch up, making it one of the earliest flags on a routine CBC. If you're chasing down unexplained fever, fatigue, or signs of infection, this number often moves before white cell count or CRP tell the full story.
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number concentration
Serum iron measures the iron circulating in your blood right now, on its way to the bone marrow to build hemoglobin. It swings with recent diet, time of day, and inflammation, so it works best alongside ferritin, TIBC, and transferrin saturation rather than alone. Low levels help investigate fatigue, weakness, pale skin, and poor exercise tolerance, while high levels can flag hemochromatosis or excess supplementation worth catching before it strains the liver and heart.
- Specimen
- Serum or plasma
- Measures
- Mass concentration
Iron saturation, also called transferrin saturation, calculates the percentage of transferrin (the protein that carries iron through your blood) that's actually loaded with iron. Low saturation points to iron deficiency, useful for investigating fatigue, hair loss, poor exercise tolerance, or restless legs, especially alongside ferritin and total iron. High saturation is the key early flag for hemochromatosis, a condition where the body absorbs too much iron and stores excess in the liver, heart, and joints.
- Specimen
- Serum or plasma
- Measures
- Mass fraction (%)
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number concentration
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number concentration
- Specimen
- Whole blood
- Measures
- Presence / threshold
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number fraction (%)
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number fraction (%)
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number concentration
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number fraction (%)
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Ratio
- Specimen
- Red blood cells
- Method
- Automated cell count
- Measures
- Mean cell volume
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number concentration
- Specimen
- Whole blood
- Method
- Automated cell count
- Measures
- Number fraction (%)
TIBC measures how much iron your blood could carry if every binding site on transferrin were filled, reflecting how hungry your body is for iron. TIBC rises when iron stores run low, since the liver produces more transferrin to hunt down whatever iron is available, and it falls with inflammation, liver disease, or iron overload. Paired with iron and ferritin, it helps distinguish true iron deficiency (high TIBC, low iron) from the low iron levels that chronic inflammation causes, useful for investigating fatigue, hair loss, poor exercise tolerance, or restless legs.
- Specimen
- Serum or plasma
- Measures
- Mass concentration
- Specimen
- Serum or plasma
- Measures
- Mass concentration
B12 lets your cells build DNA and lets nerves maintain the myelin sheath that insulates them, so levels here reveal whether your body has what it needs to make red blood cells and keep nerve signals firing cleanly. Low B12 shows up as fatigue, poor concentration, numbness or tingling, weakness, and reduced exercise tolerance, and it's common in vegetarians, vegans, people on metformin or acid-reducing medications, and those with absorption issues like low stomach acid or gut disease. Testing it establishes a baseline if you're plant-based or on these medications, and clarifies whether B12 deficiency, not just poor sleep or overtraining, is behind the fog and fatigue.
- Specimen
- Serum or plasma
- Measures
- Mass concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
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- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 1 day
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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Frequently asked questions
View all FAQsHow does pricing work?
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When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
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