Amenorrhea Panel
Three hormones that work together to explain why periods have stopped or gone missing.
Consider this test if:
- Periods have stopped or never started and you want to understand why
- Missed periods alongside milky nipple discharge, headaches, or vision changes
- Irregular cycles with low body weight, heavy training, or significant stress
- Working up early menopause or primary ovarian insufficiency
- Evaluating fertility when cycles are absent or unpredictable
- HSA/FSA eligible
- Typical results in 1 day · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No fasting required. Prolactin is sensitive to stress, sleep, exercise, and recent breast or nipple stimulation, so draw in the morning after resting quietly for a short period and avoid these beforehand. If you still have any menstrual bleeding, note the cycle day, since FSH and LH shift across the cycle. List any medications, as several (including some antipsychotics, antidepressants, and anti-nausea drugs) raise prolactin.
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What this test is for
This panel measures three pituitary and reproductive hormones together to investigate amenorrhea, the absence of menstrual periods. FSH and LH are the signals the pituitary sends to the ovaries: high levels point toward primary ovarian insufficiency or menopause, while low levels point toward a hypothalamic or pituitary cause such as stress, low body weight, or excessive exercise. Prolactin is added because elevated prolactin, often from a benign pituitary adenoma or certain medications, is a common and treatable reason periods stop. Read together, the three results help separate where the problem lies (ovary, pituitary, or hypothalamus) and direct the next step, whether that is estradiol, a thyroid check, or pituitary imaging.
The separate FSH and LH panel covers the gonadotropins alone, and the LH, FSH, and Estradiol panel adds ovarian output; this version is built specifically for the missing-period workup by including prolactin.
Biomarkers tested
Includes 3 biomarkers
FSH is the pituitary signal that drives egg maturation in the ovaries and sperm production in the testes. In women, rising FSH reflects declining ovarian reserve, making it central to fertility planning, cycle irregularity workups, and confirming perimenopause or menopause. In men, elevated FSH points to impaired sperm production, while low levels in either sex suggest the pituitary or hypothalamus isn't sending the signal at all, useful context alongside LH and estradiol.
- Specimen
- Serum or plasma
- Measures
- Concentration
LH is the pituitary signal that triggers ovulation in women and drives testosterone production in the testes of men, acting as the messenger between brain and gonads. In women, tracking LH alongside FSH and estradiol clarifies where you are in your cycle, confirms ovulation timing for fertility planning, and helps investigate irregular periods or suspected PCOS. In men, a low LH with low testosterone points to a signaling problem upstream in the pituitary, while a high LH with low testosterone points to testicular failure, a distinction that changes how low libido, fatigue, or muscle loss get treated.
- Specimen
- Serum or plasma
- Measures
- Concentration
Prolactin is made by the pituitary gland and its main job outside of pregnancy and lactation is to signal, so elevated levels suppress the reproductive hormones that drive libido, ovulation, and testosterone production. High prolactin shows up as irregular or missing periods, unexplained milk production, low libido, erectile dysfunction, or fertility difficulty, and can stem from certain medications, thyroid problems, stress, or a pituitary adenoma. If you're investigating a stalled cycle, unexplained galactorrhea, low libido, or working through a fertility workup with estradiol, FSH, and LH, prolactin tells you whether this hormone is the one crowding out the others.
- Specimen
- Serum or plasma
- Measures
- Mass concentration
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 1 day
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.
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