Alpha-2-Macroglobulin
A large plasma protein that shifts with liver, kidney, and inflammatory disease.
Consider this test if:
- Working up chronic liver disease or estimating fibrosis
- Evaluating suspected nephrotic syndrome with heavy protein loss in urine
- Investigating low results alongside pancreatitis, rheumatoid arthritis, or multiple myeloma
- Tracking a protein abnormality flagged on prior bloodwork
- HSA/FSA eligible
- Results delivered to your dashboard · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
No fasting is required. Active inflammation or infection can shift acute-phase proteins, so timing relative to recent illness is worth noting.
Video consult with your Care Team
A 1:1 call to discuss your health.
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What this test is for
Alpha-2-macroglobulin is a large protein made in the liver that binds and clears proteases (protein-digesting enzymes) and helps regulate inflammation and clotting. High levels are linked to chronic liver disease, nephrotic syndrome (where smaller proteins are lost in urine while this large one is retained), and diabetes. Low levels are seen with pancreatitis, rheumatoid arthritis, and multiple myeloma. It is not a standalone diagnosis: it is interpreted alongside liver, kidney, and inflammatory markers to clarify a clinical picture. The marker also appears as a component in liver fibrosis scoring panels, where it helps estimate scarring.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Fast, dashboard-delivered results
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
Mito Membership
$9 /mo
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Without membership
$0
pay as you go
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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