Alkaline Phosphatase (ALP)
An enzyme that flags liver, bile duct, and bone problems, often before symptoms appear.
Consider this test if:
- Investigating jaundice, itching, dark urine, or right-upper-quadrant pain that suggests a bile duct or gallbladder problem
- Following up bone pain, fractures, or a known condition like Paget's disease or vitamin D deficiency
- Tracking liver or biliary health alongside ALT, AST, and bilirubin
- An abnormal result and you need to know whether it is coming from liver or bone
- Monitoring a medication or condition known to affect the liver
- HSA/FSA eligible
- Typical results in 1 day · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
Fasting is not strictly required, but ALP is best drawn after an overnight fast, since intestinal ALP can rise in the hours after a fatty meal in certain blood types. ALP is also naturally higher during periods of bone growth and in pregnancy, which is normal and not a sign of disease.
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What this test is for
Alkaline phosphatase (ALP) is an enzyme concentrated in the liver, bile ducts, and bone, with smaller amounts in the intestine and kidneys. High ALP most commonly points to cholestasis or bile duct obstruction (where it tends to rise more than ALT and AST) or to increased bone turnover from Paget's disease, healing fractures, vitamin D deficiency, or osteomalacia; mildly low ALP is less common and is seen with zinc deficiency, malnutrition, or hypophosphatasia. Because the same number can come from either source, an isolated elevation often raises the question of liver versus bone.
This is the total ALP test, the routine screen that captures all sources combined. If it comes back high and the origin is unclear, the Alkaline Phosphatase Isoenzymes test separates liver from bone fractions, and the Bone-Specific Alkaline Phosphatase (BSAP) test isolates the bone signal for tracking metabolic bone disease.
What to expect
- 1 Book instantly
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- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 1 day
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- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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