Apr 15, 2025
Estradiol vs SHBG: Key Differences Explained
Compare Estradiol and SHBG to learn which marker is more relevant for health assessment.
Why Compare Estradiol and SHBG?
Comparing Estradiol and SHBG is crucial because they are often used to assess similar yet distinct health conditions. Understanding their differences helps in selecting the right test and interpreting the results accurately.
Estradiol vs SHBG: Which Biomarker Matters?
Estradiol and SHBG are essential biomarkers used to evaluate different health conditions. Knowing when and how to interpret these biomarkers can significantly impact clinical decision-making.
Quick Comparison Table:
Biomarker | Purpose | Ideal Range | When to Test | Key Differences |
|---|---|---|---|---|
Measures estrogen levels | 15-350 pg/mL | Monitor reproductive health | Primary estrogen in non-pregnant women | |
Binds to sex hormones | 10-57 nmol/L | Assess free hormone levels | Regulates availability of sex hormones |
Key Takeaways:
SHBG binds estradiol, affecting how much is biologically active.
High SHBG can reduce free estradiol, even if total levels look normal.
Test both to evaluate hormone activity and estrogen-related symptoms.