Gamma-Glutamyl Transferase (GGT)
A sensitive liver and bile-duct enzyme, and the most specific way to confirm where elevated alkaline phosphatase is coming from.
Consider this test if:
- An elevated alkaline phosphatase needs to be traced to liver versus bone
- Investigating abnormal liver enzymes, fatty liver, or right-upper-quadrant symptoms
- Monitoring liver health during heavy alcohol use or a period of abstinence
- Tracking liver response in metabolic conditions such as obesity or diabetes
- Following up jaundice, itching, or other signs of impaired bile flow
- HSA/FSA eligible
- Typical results in 1 day · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
Fasting for about 8 hours before the draw is preferred. Recent alcohol intake can raise GGT, so the result reflects drinking in the days before the test. The anti-seizure medications phenytoin and phenobarbital cause false elevations; if you take either, leucine aminopeptidase or 5'-nucleotidase is a better alternative. Note any liver-affecting medications or supplements for interpretation.
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What this test is for
Gamma-glutamyl transferase (GGT) is an enzyme concentrated in the liver and bile ducts that rises when bile flow is obstructed or liver cells are stressed. High GGT points to cholestasis, bile-duct obstruction, fatty liver, hepatitis, cirrhosis, and the liver effects of heavy alcohol use, and it tends to be the most sensitive of the routine liver enzymes for biliary problems. Its main practical use is sorting out an elevated alkaline phosphatase: GGT comes from liver and bile, not bone or placenta, so a high alkaline phosphatase with a high GGT confirms a liver source rather than a bone source. GGT also tracks alcohol intake well, which makes serial measurements useful for distinguishing continued drinking from abstinence, though some heavy drinkers have normal levels. It rises with increased body mass, fatty liver, and certain medications, so the result is read alongside ALT, AST, alkaline phosphatase, and bilirubin.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 1 day
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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