Aldosterone/Renin Ratio
The first-line screen for primary aldosteronism, a common and treatable cause of high blood pressure.
Consider this test if:
- Blood pressure stays high despite three or more medications
- Hypertension alongside low potassium, with or without muscle cramps and frequent urination
- High blood pressure diagnosed at a young age or with a strong family history
- A family history of primary aldosteronism or early stroke
- Looking for a treatable cause behind otherwise unexplained hypertension
- HSA/FSA eligible
- Typical results in 4-7 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
Timing and preparation matter a great deal here. Maintain a normal, unrestricted salt intake beforehand, and have blood drawn mid-morning after you have been upright (sitting, standing, or walking) for at least two hours, then seated for 5 to 15 minutes. Several drugs distort the ratio and should be stopped about four weeks ahead where clinically safe: spironolactone, eplerenone, amiloride, triamterene, potassium-wasting diuretics, and licorice-root products. Do not stop any blood pressure medication without your clinician's guidance, since some agents have minimal effect on the ratio and can be substituted.
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What this test is for
The aldosterone-to-renin ratio (ARR) compares two hormones that regulate blood pressure, sodium, and potassium. In primary aldosteronism, the adrenal glands overproduce aldosterone independently of renin, so aldosterone runs high while renin is suppressed and the ratio climbs. This is the standard screening test for that condition, which is a more common cause of hypertension than most people expect, particularly in resistant high blood pressure, hypertension with low potassium, or high blood pressure at a young age.
This ratio pairs aldosterone with plasma renin activity, which is what makes it a screen rather than a single measurement. The separate stand-alone aldosterone test measures only the hormone level and is used for narrower adrenal questions; for sorting out the cause of hypertension, the ratio is the right starting point. An elevated ARR is a screening signal, not a diagnosis, and is confirmed with dedicated suppression testing.
Biomarkers tested
Includes 3 biomarkers
- Specimen
- Serum or plasma
- Measures
- Mass concentration
- Specimen
- Plasma
- Measures
- Ratio
- Specimen
- Plasma
- Measures
- Enzyme activity
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 4-7 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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