Aldosterone/Renin Ratio
The first-line screen for primary aldosteronism, a common and treatable cause of high blood pressure.
Consider this test if:
- Blood pressure stays high despite three or more medications
- Hypertension alongside low potassium, with or without muscle cramps and frequent urination
- High blood pressure diagnosed at a young age or with a strong family history
- A family history of primary aldosteronism or early stroke
- Looking for a treatable cause behind otherwise unexplained hypertension
- HSA/FSA eligible
- Typical results in 4-7 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
Timing and preparation matter a great deal here. Maintain a normal, unrestricted salt intake beforehand, and have blood drawn mid-morning after you have been upright (sitting, standing, or walking) for at least two hours, then seated for 5 to 15 minutes. Several drugs distort the ratio and should be stopped about four weeks ahead where clinically safe: spironolactone, eplerenone, amiloride, triamterene, potassium-wasting diuretics, and licorice-root products. Do not stop any blood pressure medication without your clinician's guidance, since some agents have minimal effect on the ratio and can be substituted.
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What this test is for
The aldosterone-to-renin ratio (ARR) compares two hormones that regulate blood pressure, sodium, and potassium. In primary aldosteronism, the adrenal glands overproduce aldosterone independently of renin, so aldosterone runs high while renin is suppressed and the ratio climbs. This is the standard screening test for that condition, which is a more common cause of hypertension than most people expect, particularly in resistant high blood pressure, hypertension with low potassium, or high blood pressure at a young age.
This ratio pairs aldosterone with plasma renin activity, which is what makes it a screen rather than a single measurement. The separate stand-alone aldosterone test measures only the hormone level and is used for narrower adrenal questions; for sorting out the cause of hypertension, the ratio is the right starting point. An elevated ARR is a screening signal, not a diagnosis, and is confirmed with dedicated suppression testing.
Biomarkers tested
Includes 3 biomarkers
- Specimen
- Serum or plasma
- Measures
- Mass concentration
- Specimen
- Plasma
- Measures
- Ratio
- Specimen
- Plasma
- Measures
- Enzyme activity
What you'll learn
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Insights that connect the dots. A clinician reads your whole picture, not one result in isolation, connecting family history, past results, and lifestyle into clear next steps.
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Your personalized action plan. Nutrition, supplements, and training in one clinician-reviewed protocol, updated as your results change.
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Track your trends. Upload results from any lab and see each biomarker trend over time, so you know what is working.
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Never miss a recheck. Mito tells you what is worth retesting and when, then reminds you so nothing slips.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 4-7 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
Everything your health needs,
in one membership
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Continuous tracking, all in one place
Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
Text anytime and get clinician-reviewed answers. When you want to go deeper, 1:1 consultations are available at affordable rates.
All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost, covering the lab and what it takes to run the service. It is never a profit on the test itself. Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9 per month, and any applicable lab order or draw fee is itemized before you pay.
Where do I get tested?
Choose an available partner lab at checkout. If your cart contains multiple blood tests, Mito helps consolidate the eligible tests at one lab when possible. At-home kits and scans follow the collection or appointment process shown on their product page.
Is this eligible for HSA/FSA?
Yes. Eligible tests can be paid for with an HSA or FSA card at checkout.
When will I get my results?
Your results appear in your Mito dashboard after the laboratory completes processing. A clinician then reviews them before your analysis and personalized action plan are finalized. Timing varies by test, and specialty assays and at-home kits may take longer.
Do I need a physician's order?
No. Mito provides the laboratory order when one is required, so you do not need to arrange a separate physician visit before purchasing.
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