17-Hydroxyprogesterone (17-OHP)
The key marker for congenital adrenal hyperplasia and an underrecognized cause of androgen excess.
Consider this test if:
- Hirsutism, persistent acne, irregular cycles, or unexplained infertility, especially with a PCOS-like picture
- A personal or family history of congenital adrenal hyperplasia
- Signs of early or rapid puberty in a child, or premature pubic hair
- Distinguishing nonclassic CAH from polycystic ovary syndrome
- Monitoring adrenal androgen control if you already have a CAH diagnosis
- HSA/FSA eligible
- Typical results in 3-7 days · Reviewed by a real clinician
- Drawn at a CLIA/CAP-accredited lab near you ·
Pre-test considerations
Draw the sample early in the morning, since 17-OHP follows a daily rhythm and peaks in the morning. In menstruating women it is best measured in the follicular phase, before ovulation. If you are being treated for CAH, the standard is to collect before your morning glucocorticoid dose. Fasting is not required.
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What this test is for
17-hydroxyprogesterone is a steroid precursor the adrenal glands use to make cortisol. When the enzyme 21-hydroxylase is deficient, the pathway backs up and 17-OHP rises sharply, which makes it the primary marker for congenital adrenal hyperplasia (CAH). Markedly elevated levels point to classic CAH, while milder elevations suggest the nonclassic form, a relatively common and often overlooked cause of hirsutism, acne, irregular periods, and infertility in women that can look very much like PCOS. It is also used to help assess certain hormone-producing adrenal or ovarian tumors. Because nonclassic CAH is frequently mistaken for PCOS, a borderline result is usually clarified with an ACTH (cosyntropin) stimulation test.
What to expect
- 1 Book instantly
Click, book, done. Choose a convenient lab location near you. Transparent, up-front pricing.
- 2 Quick lab visit
Testing to fit your busy schedule, usually 15 minutes or less. Walk-in and appointments available.
- 3 Typical results in 3-7 days
Your results post straight to your dashboard as soon as the lab completes them.
- 4 Expert guidance
Included with Mito membership. A clinician reviews your results and your personalized action plan follows, with clear next steps.
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Every test at our cost
Members pay our cost on every test, with lab fees passed straight through. The full receipt is itemized, never padded.
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Upload past labs and watch your trends over time. Every marker and visit lives in one longitudinal record, so all your care stays together.
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Year-round clinician support
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All for $9/month
Order any test or consult without joining. For $9/month, members unlock member prices, trend tracking, and year-round clinician guidance.
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Frequently asked questions
View all FAQsHow does pricing work?
Every test shows the member price next to the standard non-member price, so you can see what membership saves you. The member price is our cost — covering the lab and what it takes to run the service — never a profit on the test itself; Mito makes its money on the $9 membership, not on marking up your tests. Membership is $9/mo, and you still pay the lab’s order fee. Prices are itemized before you pay, with no hidden fees.
Where do I get tested?
Choose a partner lab (Quest, Labcorp, or BioReference) at checkout. If your cart spans multiple tests, we consolidate the whole order onto a single lab so you only make one visit.
Is this eligible for HSA/FSA?
Yes. This test is HSA/FSA eligible, and you can pay with your HSA/FSA card at checkout.
When will I get my results?
Your results post to your dashboard once your lab completes them, then a clinician reviews them and your full analysis and personalized action plan (with clear next steps) follow. Turnaround varies by test: specialty assays and at-home kits take longer, and each test shows its expected turnaround before you buy.
Do I need a doctor’s order?
No. Mito provides the lab order for you, so you can book and get tested without a separate doctor visit.
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