Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
eGFRcr-cys vs Urea: Key Differences Explained
Discover the differences between eGFRcr-cys and Urea to understand their health implications.

Written by
Mito Team

Introduction
Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) are key diagnostic tools for evaluating kidney function and metabolic health. Comparing these markers helps healthcare providers determine the most appropriate test based on specific clinical conditions like renal filtration efficiency, nitrogen waste levels, or chronic kidney disease risk.
What Is Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys)?
Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) measures how well your kidneys remove nitrogen-based waste (urea) from the blood. It’s often used to screen for dehydration, high protein intake, or impaired renal clearance.
What Is BUN (Urea)?
BUN (Urea) provides complementary insights into kidney performance, especially for estimating glomerular filtration rate or understanding renal stress through ratio-based or creatinine-based formulas.
Comparison Table
Category | Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) | BUN (Urea) |
---|---|---|
Primary Function | Assesses nitrogen waste (urea) | Estimates filtration rate or renal output |
Diagnostic Relevance | Monitors hydration, protein metabolism | Detects early kidney dysfunction |
Test Type | Blood test | Blood test |
Sample Required | Blood sample | Blood sample |
Preparation Needed | None typically required | Fasting optional but not required |
Optimal Range | 6–20 mg/dL (BUN) | Varies by method, age, sex |
Factors That Influence | Dehydration, diet, bleeding | Muscle mass, kidney health, hydration |
Clinical Use Cases | Kidney disease, protein disorders | CKD staging, routine renal panels |
When to Test
Your provider may recommend testing Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) if you're experiencing symptoms like swelling, fatigue, decreased urine output, or changes in hydration. They're also used for ongoing monitoring in patients with hypertension, diabetes, or known kidney conditions.
FAQs
Can I test for Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) together?
Yes, these tests are often bundled in comprehensive metabolic panels or renal panels.
Which is more accurate for early kidney damage?
BUN (Urea) may offer better insight into glomerular filtration rate, a key indicator for early-stage renal disease.
What affects test accuracy?
Hydration status, medications, and recent diet can all impact values for both Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea).
eGFRcr-cys vs Urea: Key Differences Explained
Discover the differences between eGFRcr-cys and Urea to understand their health implications.

Written by
Mito Team

Introduction
Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) are key diagnostic tools for evaluating kidney function and metabolic health. Comparing these markers helps healthcare providers determine the most appropriate test based on specific clinical conditions like renal filtration efficiency, nitrogen waste levels, or chronic kidney disease risk.
What Is Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys)?
Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) measures how well your kidneys remove nitrogen-based waste (urea) from the blood. It’s often used to screen for dehydration, high protein intake, or impaired renal clearance.
What Is BUN (Urea)?
BUN (Urea) provides complementary insights into kidney performance, especially for estimating glomerular filtration rate or understanding renal stress through ratio-based or creatinine-based formulas.
Comparison Table
Category | Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) | BUN (Urea) |
---|---|---|
Primary Function | Assesses nitrogen waste (urea) | Estimates filtration rate or renal output |
Diagnostic Relevance | Monitors hydration, protein metabolism | Detects early kidney dysfunction |
Test Type | Blood test | Blood test |
Sample Required | Blood sample | Blood sample |
Preparation Needed | None typically required | Fasting optional but not required |
Optimal Range | 6–20 mg/dL (BUN) | Varies by method, age, sex |
Factors That Influence | Dehydration, diet, bleeding | Muscle mass, kidney health, hydration |
Clinical Use Cases | Kidney disease, protein disorders | CKD staging, routine renal panels |
When to Test
Your provider may recommend testing Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) if you're experiencing symptoms like swelling, fatigue, decreased urine output, or changes in hydration. They're also used for ongoing monitoring in patients with hypertension, diabetes, or known kidney conditions.
FAQs
Can I test for Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) together?
Yes, these tests are often bundled in comprehensive metabolic panels or renal panels.
Which is more accurate for early kidney damage?
BUN (Urea) may offer better insight into glomerular filtration rate, a key indicator for early-stage renal disease.
What affects test accuracy?
Hydration status, medications, and recent diet can all impact values for both Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea).
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
eGFRcr-cys vs Urea: Key Differences Explained
Discover the differences between eGFRcr-cys and Urea to understand their health implications.

Written by
Mito Team

Introduction
Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) are key diagnostic tools for evaluating kidney function and metabolic health. Comparing these markers helps healthcare providers determine the most appropriate test based on specific clinical conditions like renal filtration efficiency, nitrogen waste levels, or chronic kidney disease risk.
What Is Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys)?
Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) measures how well your kidneys remove nitrogen-based waste (urea) from the blood. It’s often used to screen for dehydration, high protein intake, or impaired renal clearance.
What Is BUN (Urea)?
BUN (Urea) provides complementary insights into kidney performance, especially for estimating glomerular filtration rate or understanding renal stress through ratio-based or creatinine-based formulas.
Comparison Table
Category | Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) | BUN (Urea) |
---|---|---|
Primary Function | Assesses nitrogen waste (urea) | Estimates filtration rate or renal output |
Diagnostic Relevance | Monitors hydration, protein metabolism | Detects early kidney dysfunction |
Test Type | Blood test | Blood test |
Sample Required | Blood sample | Blood sample |
Preparation Needed | None typically required | Fasting optional but not required |
Optimal Range | 6–20 mg/dL (BUN) | Varies by method, age, sex |
Factors That Influence | Dehydration, diet, bleeding | Muscle mass, kidney health, hydration |
Clinical Use Cases | Kidney disease, protein disorders | CKD staging, routine renal panels |
When to Test
Your provider may recommend testing Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) if you're experiencing symptoms like swelling, fatigue, decreased urine output, or changes in hydration. They're also used for ongoing monitoring in patients with hypertension, diabetes, or known kidney conditions.
FAQs
Can I test for Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) together?
Yes, these tests are often bundled in comprehensive metabolic panels or renal panels.
Which is more accurate for early kidney damage?
BUN (Urea) may offer better insight into glomerular filtration rate, a key indicator for early-stage renal disease.
What affects test accuracy?
Hydration status, medications, and recent diet can all impact values for both Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea).
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
eGFRcr-cys vs Urea: Key Differences Explained
Discover the differences between eGFRcr-cys and Urea to understand their health implications.

Written by
Mito Team

Introduction
Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) are key diagnostic tools for evaluating kidney function and metabolic health. Comparing these markers helps healthcare providers determine the most appropriate test based on specific clinical conditions like renal filtration efficiency, nitrogen waste levels, or chronic kidney disease risk.
What Is Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys)?
Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) measures how well your kidneys remove nitrogen-based waste (urea) from the blood. It’s often used to screen for dehydration, high protein intake, or impaired renal clearance.
What Is BUN (Urea)?
BUN (Urea) provides complementary insights into kidney performance, especially for estimating glomerular filtration rate or understanding renal stress through ratio-based or creatinine-based formulas.
Comparison Table
Category | Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) | BUN (Urea) |
---|---|---|
Primary Function | Assesses nitrogen waste (urea) | Estimates filtration rate or renal output |
Diagnostic Relevance | Monitors hydration, protein metabolism | Detects early kidney dysfunction |
Test Type | Blood test | Blood test |
Sample Required | Blood sample | Blood sample |
Preparation Needed | None typically required | Fasting optional but not required |
Optimal Range | 6–20 mg/dL (BUN) | Varies by method, age, sex |
Factors That Influence | Dehydration, diet, bleeding | Muscle mass, kidney health, hydration |
Clinical Use Cases | Kidney disease, protein disorders | CKD staging, routine renal panels |
When to Test
Your provider may recommend testing Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) if you're experiencing symptoms like swelling, fatigue, decreased urine output, or changes in hydration. They're also used for ongoing monitoring in patients with hypertension, diabetes, or known kidney conditions.
FAQs
Can I test for Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea) together?
Yes, these tests are often bundled in comprehensive metabolic panels or renal panels.
Which is more accurate for early kidney damage?
BUN (Urea) may offer better insight into glomerular filtration rate, a key indicator for early-stage renal disease.
What affects test accuracy?
Hydration status, medications, and recent diet can all impact values for both Estimated Glomerular Filtration Rate Creatinine-CystatinC (eGFRcr-cys) and BUN (Urea).
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Clinician reviewed insights & Action Plan
Complete with exercise, nutrition, and supplement recommendations

1:1 Clinician consult
Receive expert guidance on how to manage and reduce your health risks

Upload past labs for lifetime tracking
All your medical records in one secure dashboard

Biological age
Understand your biological age and track your pace of aging

Access to advanced diagnostics
Unlock discounts on all other blood tests and scans
Premium care made accessible.
HSA/FSA eligible
One-time payment
No hidden fees or subscription traps
Buy more & save:
Individual
$50 off (Save 13%)
$349
$399
Duo Bundle (For 2)
$334 per person
$668
$798
popular
★ ★ ★ ★ ★
Trusted by thousands of members
What could cost you $15,000? $349 with Mito.
What's included

Comprehensive Lab Test
100+ biomarkers - Test at 2,000+ lab locations nationwide

Clinician reviewed insights & Action Plan
Complete with exercise, nutrition, and supplement recommendations

1:1 Clinician consult
Receive expert guidance on how to manage and reduce your health risks

Upload past labs for lifetime tracking
All your medical records in one secure dashboard

Biological age
Understand your biological age and track your pace of aging

Access to advanced diagnostics
Unlock discounts on all other blood tests and scans
Premium care made accessible.
HSA/FSA eligible
One-time payment
No hidden fees or subscription traps
Buy more & save:
Individual
$50 off (Save 13%)
$349
$399
Duo Bundle (For 2)
$334 per person
$668
$798
popular
★ ★ ★ ★ ★
Trusted by thousands of members
What could cost you $15,000? $349 with Mito.
What's included

Comprehensive Lab Test
100+ biomarkers - Test at 2,000+ lab locations nationwide

Clinician reviewed insights & Action Plan
Complete with exercise, nutrition, and supplement recommendations

1:1 Clinician consult
Receive expert guidance on how to manage and reduce your health risks

Upload past labs for lifetime tracking
All your medical records in one secure dashboard

Biological age
Understand your biological age and track your pace of aging

Access to advanced diagnostics
Unlock discounts on all other blood tests and scans
Premium care made accessible.
HSA/FSA eligible
One-time payment
No hidden fees or subscription traps
Buy more & save:
Individual
$50 off (Save 13%)
$349
$399
Duo Bundle (For 2)
$334 per person
$668
$798
popular
★ ★ ★ ★ ★
Trusted by thousands of members