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Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Jun 18, 2025

High Folate Levels: How Much Folic Acid Is Too Much?

We need folate for energy, mood, and more—but too much can backfire. Here’s how to get the right amount for your body.

Biomarkers

Written by

Mito Team

High Folate Levels: How Much Folic Acid Is Too Much?
High Folate Levels: How Much Folic Acid Is Too Much?
High Folate Levels: How Much Folic Acid Is Too Much?
High Folate Levels: How Much Folic Acid Is Too Much?

You’ve probably heard that folate—or folic acid, is an essential vitamin. It’s true. Folate helps your body make healthy red blood cells, supports your brain and nervous system, and is crucial during pregnancy to prevent birth defects.

But here’s the twist: while not getting enough folate is risky, too much can also cause problems.

Today, many people are getting more folic acid than they realize from fortified foods, multivitamins, and supplements. 

What Is Folate, and Why Do You Need It?

Folate is a B vitamin (specifically vitamin B9) found naturally in foods like leafy greens, beans, and liver. Folic acid is the synthetic version used in supplements and added to many packaged foods like bread, cereal, and pasta.

Your body uses folate to:

  • Make DNA and red blood cells

  • Support healthy brain and nerve function

  • Detoxify harmful compounds

  • Reduce homocysteine, a marker linked to heart disease

Folate is especially important during pregnancy to prevent neural tube defects in babies. That’s why many governments require folic acid to be added to foods.

Where You Might Be Getting More Than You Think

Where You Might Be Getting More Than You Think

Most people get folate from a combination of:

  • Whole foods like spinach, lentils, and citrus fruits

  • Fortified foods, including breakfast cereal, bread, and pasta

  • Supplements such as multivitamins, prenatal vitamins, and energy drinks

This layering effect adds up quickly. You might be taking a supplement with 400 to 800 micrograms (µg) of folic acid, eating fortified cereal with another 400 µg, and having pasta or snacks that add even more.

So, how much is too much folic acid? According to the CDC, the upper safe limit (UL) for folic acid from supplements and fortified foods is 1,000 µg per day (1 mg). Going over that regularly may increase the risk of adverse effects in certain people.

What Does High Folate Mean?

If your blood test shows high folate levels, you’re not alone. This is more common than ever, especially in countries with food fortification programs.

A folate level greater than 20 ng/mL on a blood test is typically considered elevated. This doesn’t always mean something is wrong, but it can be a signal that your body is getting more folic acid than it needs.

What causes high folate levels?

Common causes include:

  • Taking high-dose folic acid supplements (especially more than 800 µg daily)

  • Eating a diet rich in fortified foods

  • Poor metabolism of folic acid due to genetic variants (like MTHFR)

What are the symptoms of high folate levels?

High folate levels don’t always cause noticeable symptoms. But some people may experience:

  • Digestive upset

  • Difficulty concentrating

  • Sleep problems

  • Tingling or numbness (if paired with a hidden B12 deficiency)

High folic acid levels can also mask a vitamin B12 deficiency, which can silently damage your nervous system over time. This is why folate and B12 should always be tested together.

The Risks of Too Much Folic Acid

The Risks of Too Much Folic Acid

Too much folic acid might not seem like a big deal, but research shows it’s worth taking seriously:

  • Unmetabolized folic acid (UMFA): When the body can’t fully convert folic acid to active folate, it builds up in the blood. While the long-term effects are still being studied, UMFA has been linked to altered immune responses and possible effects on brain function.

  • Masking B12 deficiency: As mentioned, high folic acid can hide anemia caused by B12 deficiency, allowing nerve damage to progress silently.

  • Cancer concerns: Some studies suggest excess folic acid, especially 1 to 2 mg per day, may increase the risk of certain cancers, like prostate or colorectal cancer, in some people. Other studies show neutral or even protective effects. The research is still evolving.

Bottom line: more isn’t always better.

How to Optimize Folate Levels Safely

So, how do you keep folate in the sweet spot—not too low, not too high?

1. Start with a blood test

Test your folate, B12, and homocysteine levels. These give you a clearer picture of your true folate status and how well your body is using it. If your folate level is greater than 20, your provider may recommend adjustments.

2. Prioritize folate-rich foods

Get your folate the natural way. Add these folate-rich foods to your diet:

  • Spinach

  • Asparagus

  • Avocado

  • Chickpeas

  • Liver

  • Oranges

Natural folate doesn’t carry the same risk of buildup as synthetic folic acid.

3. Be cautious with supplements

Unless you’re pregnant or deficient, you may not need high-dose folic acid. If you do supplement, consider using methylated folate (like 5-MTHF), especially if you have an MTHFR variant. This form is easier for your body to use.

How to Lower High Folate Levels (If Needed)

How to Lower High Folate Levels (If Needed)

If your bloodwork shows high folic acid or folate levels:

  • Review your diet for fortified foods and scale back if needed.

  • Switch to a lower-dose supplement or stop temporarily under guidance.

  • Use methylfolate instead of folic acid, particularly if you have trouble metabolizing it.

  • Recheck your levels in a few months to monitor improvement.

Smarter Testing For Your Folate Levels

Folate is essential, but too much of a good thing can become a problem. With today’s fortified foods and widespread supplement use, high folate levels are more common than ever.

At Mito Health, our comprehensive blood panel looks at your folate, B12, and homocysteine levels. Then we help you adjust your nutrition and supplement plan with precision, not just generic advice. We also make sure you’re not accidentally masking a B12 deficiency or stacking nutrients that may cause long-term issues.

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The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

© 2025 Mito Health Inc.

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The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

© 2025 Mito Health Inc.

Company

Inquire

Join our newsletter

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

© 2025 Mito Health Inc.