Apr 15, 2025
SHBG vs DHEA-S: Key Differences Explained
Compare SHBG and DHEA-S to learn which marker is more relevant for health assessment.
Why Compare SHBG and DHEA-S?
Comparing SHBG and DHEA-S is crucial because they are often used to assess similar yet distinct health conditions. Understanding their differences helps in selecting the right test and interpreting the results accurately.
SHBG vs DHEA-S: Which Biomarker Matters?
SHBG and DHEA-S are essential biomarkers used to evaluate different health conditions. Knowing when and how to interpret these biomarkers can significantly impact clinical decision-making.
Quick Comparison Table:
Biomarker | Purpose | Ideal Range | When to Test | Key Differences |
|---|---|---|---|---|
Binds to sex hormones | 10-57 nmol/L | Assess free hormone levels | Regulates availability of sex hormones | |
Measures adrenal androgen levels | 35-430 µg/dL | Evaluate adrenal function | Indicator of adrenal output |
Key Takeaways:
SHBG binds hormones; DHEA-S is a weak androgen from the adrenal glands.
High DHEA-S with low SHBG may increase free androgens.
Test both to investigate causes of acne, hair changes, or cycle disruption.