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Free Testosterone vs DHEA-S: Key Differences Explained
Discover the differences between Free Testosterone and DHEA-S to understand their health implications.
Written by
Mito Team
Introduction
Free Testosterone and DHEA-S are essential biomarkers used to evaluate kidney function and overall metabolic health.
What Is Free Testosterone?
Free Testosterone helps assess the body’s ability to filter waste and maintain fluid balance.
What Is DHEA-S?
DHEA-S gives clinicians a ratio-based insight, often improving diagnostic accuracy in conjunction with Free Testosterone.
Comparison Table
Feature | FREE-TESTOSTERONE | DHEA-S |
|---|---|---|
Primary Role | FREE-TESTOSTERONE plays a key role in regulating hormonal or metabolic balance. | DHEA-S is critical in endocrine function and systemic homeostasis. |
Hormonal Pathway | Acts in pathways linked to free-testosterone signaling or feedback. | Works within hormone receptor or production networks. |
Diagnostic Relevance | Abnormal free-testosterone levels may indicate dysfunction in glucose regulation, fertility, or endocrine glands. | Used to identify or monitor issues like hormone imbalance, reproductive disorders, or metabolic resistance. |
Use in Hormone Therapy | Guides treatment planning for patients with disrupted free-testosterone levels. | Frequently assessed before or during hormone replacement or suppression therapy. |
Feedback Sensitivity | FREE-TESTOSTERONE levels often fluctuate based on other hormone signals. | DHEA-S responds to internal cues and endocrine feedback loops. |
Measurement | Units vary (e.g., pmol/L, ng/dL, µIU/mL) depending on test type. | May require fasting or timed sample for accuracy. |
Normal Range | Reference ranges vary by sex, age, and clinical setting. | Must be interpreted in context of other hormones. |
Clinical Application | Often ordered when evaluating hormonal status or metabolic syndrome via FREE-TESTOSTERONE. | Used in tandem with FREE-TESTOSTERONE for full endocrine assessment. |
What They Tell You
Free Testosterone provides foundational insight, while DHEA-S enhances interpretation when both markers are tested together.
Clinical Use Cases
Doctors may order both tests when investigating causes of fatigue, swelling, or changes in urine output.
Which One Should You Get?
Often, both are tested together to interpret kidney function more precisely, especially in hospitalized or chronic care patients.
Can They Be Used Together?
Yes. Combined interpretation offers more context and accuracy in diagnosing renal and systemic conditions.
When to See a Doctor
If either Free Testosterone or DHEA-S shows abnormal trends, especially with symptoms, follow up with a nephrologist or primary care provider.
FAQs
Does diet affect the results? Yes, high protein intake or dehydration can shift values.
Can I rely on just one? The ratio (DHEA-S) is only meaningful when Free Testosterone and BUN are both measured.
Are these tests routine? Yes, especially for those with risk factors like diabetes or high blood pressure.
Optional Value-Add
In Seniors: These values change with age and muscle mass decline.
In Women: Hormonal cycles and hydration status may influence interpretation.
In Athletes: High protein intake or muscle turnover can affect levels.
Free Testosterone vs DHEA-S: Key Differences Explained
Discover the differences between Free Testosterone and DHEA-S to understand their health implications.
Written by
Mito Team
Introduction
Free Testosterone and DHEA-S are essential biomarkers used to evaluate kidney function and overall metabolic health.
What Is Free Testosterone?
Free Testosterone helps assess the body’s ability to filter waste and maintain fluid balance.
What Is DHEA-S?
DHEA-S gives clinicians a ratio-based insight, often improving diagnostic accuracy in conjunction with Free Testosterone.
Comparison Table
Feature | FREE-TESTOSTERONE | DHEA-S |
|---|---|---|
Primary Role | FREE-TESTOSTERONE plays a key role in regulating hormonal or metabolic balance. | DHEA-S is critical in endocrine function and systemic homeostasis. |
Hormonal Pathway | Acts in pathways linked to free-testosterone signaling or feedback. | Works within hormone receptor or production networks. |
Diagnostic Relevance | Abnormal free-testosterone levels may indicate dysfunction in glucose regulation, fertility, or endocrine glands. | Used to identify or monitor issues like hormone imbalance, reproductive disorders, or metabolic resistance. |
Use in Hormone Therapy | Guides treatment planning for patients with disrupted free-testosterone levels. | Frequently assessed before or during hormone replacement or suppression therapy. |
Feedback Sensitivity | FREE-TESTOSTERONE levels often fluctuate based on other hormone signals. | DHEA-S responds to internal cues and endocrine feedback loops. |
Measurement | Units vary (e.g., pmol/L, ng/dL, µIU/mL) depending on test type. | May require fasting or timed sample for accuracy. |
Normal Range | Reference ranges vary by sex, age, and clinical setting. | Must be interpreted in context of other hormones. |
Clinical Application | Often ordered when evaluating hormonal status or metabolic syndrome via FREE-TESTOSTERONE. | Used in tandem with FREE-TESTOSTERONE for full endocrine assessment. |
What They Tell You
Free Testosterone provides foundational insight, while DHEA-S enhances interpretation when both markers are tested together.
Clinical Use Cases
Doctors may order both tests when investigating causes of fatigue, swelling, or changes in urine output.
Which One Should You Get?
Often, both are tested together to interpret kidney function more precisely, especially in hospitalized or chronic care patients.
Can They Be Used Together?
Yes. Combined interpretation offers more context and accuracy in diagnosing renal and systemic conditions.
When to See a Doctor
If either Free Testosterone or DHEA-S shows abnormal trends, especially with symptoms, follow up with a nephrologist or primary care provider.
FAQs
Does diet affect the results? Yes, high protein intake or dehydration can shift values.
Can I rely on just one? The ratio (DHEA-S) is only meaningful when Free Testosterone and BUN are both measured.
Are these tests routine? Yes, especially for those with risk factors like diabetes or high blood pressure.
Optional Value-Add
In Seniors: These values change with age and muscle mass decline.
In Women: Hormonal cycles and hydration status may influence interpretation.
In Athletes: High protein intake or muscle turnover can affect levels.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Free Testosterone vs DHEA-S: Key Differences Explained
Discover the differences between Free Testosterone and DHEA-S to understand their health implications.
Written by
Mito Team
Introduction
Free Testosterone and DHEA-S are essential biomarkers used to evaluate kidney function and overall metabolic health.
What Is Free Testosterone?
Free Testosterone helps assess the body’s ability to filter waste and maintain fluid balance.
What Is DHEA-S?
DHEA-S gives clinicians a ratio-based insight, often improving diagnostic accuracy in conjunction with Free Testosterone.
Comparison Table
Feature | FREE-TESTOSTERONE | DHEA-S |
|---|---|---|
Primary Role | FREE-TESTOSTERONE plays a key role in regulating hormonal or metabolic balance. | DHEA-S is critical in endocrine function and systemic homeostasis. |
Hormonal Pathway | Acts in pathways linked to free-testosterone signaling or feedback. | Works within hormone receptor or production networks. |
Diagnostic Relevance | Abnormal free-testosterone levels may indicate dysfunction in glucose regulation, fertility, or endocrine glands. | Used to identify or monitor issues like hormone imbalance, reproductive disorders, or metabolic resistance. |
Use in Hormone Therapy | Guides treatment planning for patients with disrupted free-testosterone levels. | Frequently assessed before or during hormone replacement or suppression therapy. |
Feedback Sensitivity | FREE-TESTOSTERONE levels often fluctuate based on other hormone signals. | DHEA-S responds to internal cues and endocrine feedback loops. |
Measurement | Units vary (e.g., pmol/L, ng/dL, µIU/mL) depending on test type. | May require fasting or timed sample for accuracy. |
Normal Range | Reference ranges vary by sex, age, and clinical setting. | Must be interpreted in context of other hormones. |
Clinical Application | Often ordered when evaluating hormonal status or metabolic syndrome via FREE-TESTOSTERONE. | Used in tandem with FREE-TESTOSTERONE for full endocrine assessment. |
What They Tell You
Free Testosterone provides foundational insight, while DHEA-S enhances interpretation when both markers are tested together.
Clinical Use Cases
Doctors may order both tests when investigating causes of fatigue, swelling, or changes in urine output.
Which One Should You Get?
Often, both are tested together to interpret kidney function more precisely, especially in hospitalized or chronic care patients.
Can They Be Used Together?
Yes. Combined interpretation offers more context and accuracy in diagnosing renal and systemic conditions.
When to See a Doctor
If either Free Testosterone or DHEA-S shows abnormal trends, especially with symptoms, follow up with a nephrologist or primary care provider.
FAQs
Does diet affect the results? Yes, high protein intake or dehydration can shift values.
Can I rely on just one? The ratio (DHEA-S) is only meaningful when Free Testosterone and BUN are both measured.
Are these tests routine? Yes, especially for those with risk factors like diabetes or high blood pressure.
Optional Value-Add
In Seniors: These values change with age and muscle mass decline.
In Women: Hormonal cycles and hydration status may influence interpretation.
In Athletes: High protein intake or muscle turnover can affect levels.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Free Testosterone vs DHEA-S: Key Differences Explained
Discover the differences between Free Testosterone and DHEA-S to understand their health implications.
Written by
Mito Team
Introduction
Free Testosterone and DHEA-S are essential biomarkers used to evaluate kidney function and overall metabolic health.
What Is Free Testosterone?
Free Testosterone helps assess the body’s ability to filter waste and maintain fluid balance.
What Is DHEA-S?
DHEA-S gives clinicians a ratio-based insight, often improving diagnostic accuracy in conjunction with Free Testosterone.
Comparison Table
Feature | FREE-TESTOSTERONE | DHEA-S |
|---|---|---|
Primary Role | FREE-TESTOSTERONE plays a key role in regulating hormonal or metabolic balance. | DHEA-S is critical in endocrine function and systemic homeostasis. |
Hormonal Pathway | Acts in pathways linked to free-testosterone signaling or feedback. | Works within hormone receptor or production networks. |
Diagnostic Relevance | Abnormal free-testosterone levels may indicate dysfunction in glucose regulation, fertility, or endocrine glands. | Used to identify or monitor issues like hormone imbalance, reproductive disorders, or metabolic resistance. |
Use in Hormone Therapy | Guides treatment planning for patients with disrupted free-testosterone levels. | Frequently assessed before or during hormone replacement or suppression therapy. |
Feedback Sensitivity | FREE-TESTOSTERONE levels often fluctuate based on other hormone signals. | DHEA-S responds to internal cues and endocrine feedback loops. |
Measurement | Units vary (e.g., pmol/L, ng/dL, µIU/mL) depending on test type. | May require fasting or timed sample for accuracy. |
Normal Range | Reference ranges vary by sex, age, and clinical setting. | Must be interpreted in context of other hormones. |
Clinical Application | Often ordered when evaluating hormonal status or metabolic syndrome via FREE-TESTOSTERONE. | Used in tandem with FREE-TESTOSTERONE for full endocrine assessment. |
What They Tell You
Free Testosterone provides foundational insight, while DHEA-S enhances interpretation when both markers are tested together.
Clinical Use Cases
Doctors may order both tests when investigating causes of fatigue, swelling, or changes in urine output.
Which One Should You Get?
Often, both are tested together to interpret kidney function more precisely, especially in hospitalized or chronic care patients.
Can They Be Used Together?
Yes. Combined interpretation offers more context and accuracy in diagnosing renal and systemic conditions.
When to See a Doctor
If either Free Testosterone or DHEA-S shows abnormal trends, especially with symptoms, follow up with a nephrologist or primary care provider.
FAQs
Does diet affect the results? Yes, high protein intake or dehydration can shift values.
Can I rely on just one? The ratio (DHEA-S) is only meaningful when Free Testosterone and BUN are both measured.
Are these tests routine? Yes, especially for those with risk factors like diabetes or high blood pressure.
Optional Value-Add
In Seniors: These values change with age and muscle mass decline.
In Women: Hormonal cycles and hydration status may influence interpretation.
In Athletes: High protein intake or muscle turnover can affect levels.
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Billed annually - cancel anytime
Bundle options:
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$399
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or 4 interest-free payments of $87.25*
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(For 2)
$798
$668
/year
or 4 interest-free payments of $167*
Pricing for members in NY, NJ & RI may vary.
Checkout with HSA/FSA
Secure, private platform
What's included
Comprehensive lab testing (Core)
100+ biomarkers - Test at 2,000+ labs nationwide
In-depth health insights & action plan
Expert designed recommendations across exercise, nutrition, and supplements
1:1 Consultation
Meet with your dedicated care team to review your results and define next steps
Lifetime health record tracking
Upload past labs and monitor your progress over time
Biological age analysis
See how your body is aging and what’s driving it
Order add-on tests and scans anytime
Access to advanced diagnostics at discounted rates for members
Concierge-level care, made accessible.
Mito Health Membership
Codeveloped with experts at MIT & Stanford
Less than $1/ day
Billed annually - cancel anytime
Bundle options:
Individual
$399
$349
/year
or 4 interest-free payments of $87.25*
Duo Bundle (For 2)
$798
$668
/year
or 4 interest-free payments of $167*
Pricing for members in NY, NJ & RI may vary.
Checkout with HSA/FSA
Secure, private platform
What's included
Comprehensive lab testing (Core)
100+ biomarkers - Test at 2,000+ labs nationwide
In-depth health insights & action plan
Expert designed recommendations across exercise, nutrition, and supplements
1:1 Consultation
Meet with your dedicated care team to review your results and define next steps
Lifetime health record tracking
Upload past labs and monitor your progress over time
Biological age analysis
See how your body is aging and what’s driving it
Order add-on tests and scans anytime
Access to advanced diagnostics at discounted rates for members
Concierge-level care, made accessible.
Mito Health Membership
Codeveloped with experts at MIT & Stanford
Less than $1/ day
Billed annually - cancel anytime
Bundle options:
Individual
$399
$349
/year
or 4 payments of $87.25*
Duo Bundle
(For 2)
$798
$668
/year
or 4 payments of $167*
Pricing for members in NY, NJ & RI may vary.
Checkout with HSA/FSA
Secure, private platform