Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
The Best Prebiotic Supplements For Your Microbiome
Learn how to think about supplements thoughtfully when intake falls short.

Written by
Mito Team

What are prebiotics, and why they matter
Prebiotics are specific types of dietary fiber that resist digestion in the small intestine and reach the colon, where they serve as food for beneficial gut microbes. When these microbes ferment prebiotic fibers they produce short-chain fatty acids (SCFAs) such as butyrate, which help fuel colon cells, reduce inflammation, support the gut barrier, and influence metabolism and the brain through the gut–brain axis. Regular intake of prebiotic fiber supports microbial diversity, increases SCFA-producing bacteria, and is associated with lower risk factors for conditions like high cholesterol, blood sugar dysregulation, and some types of colorectal disease.
Whole foods first
The simplest, safest approach is to get prebiotic fibers from whole plant foods. Whole foods bring fiber together with vitamins, minerals, polyphenols and other nutrients that support overall health and the microbiome. Examples of prebiotic-rich foods include:
Chicory root, Jerusalem artichoke, onions, garlic, leeks, asparagus (inulin and FOS)
Legumes and some dairy-derived products (GOS or galactooligosaccharides in supplement form)
Underripe bananas and plantains, broccoli and other cruciferous vegetables (non-starch polysaccharides that can discourage harmful bacteria)
Many people benefit from raising total fiber intake toward common targets around 30 g/day; some populations with high microbial diversity consume 40–50 g/day. When access to a varied, plant-rich diet is limited (travel, restricted food choices, or certain clinical situations), a prebiotic supplement can be a practical, evidence-informed addition.
When should you supplement?
Use a supplement if you:
Struggle to reach prebiotic-rich foods regularly
Need

a targeted dose for a specific goal (e.g., increase bifidobacteria or SCFA production)
Have dietary restrictions, long travel, or limited options
Are working with a clinician to modify the microbiome for a health condition
How to choose the best prebiotic supplement
Look for these features:
Broad-spectrum formulation or single-fiber match to your goals
Broad-spectrum blends (inulin + FOS + GOS + other fermentable fibers) feed a wider range of beneficial microbes and are a good general choice for increasing diversity and SCFA production.
Single fibers (e.g., GOS alone) can be useful if you or your clinician want a targeted effect or you have sensitivity to other fibers.
Clear, realistic dosing
Effective supplement doses typically fall in the 5–10 g/day range. Many products list amounts per serving; choose one that matches your plan and be prepared to adjust.
Purity and additives
Prefer products with minimal added sugars, fillers, or unnecessary flavorings.
Third-party testing and accurate labeling
Some supplements have been shown to contain less active ingredient than listed. Choosing products that have been third‑party tested for content and purity reduces that risk. Examples of third-party tested options include Hyperbiotics Prebiotic, InnovixLabs Broad Spectrum Prebiotic Fiber, and Benefiber Prebiotic Fiber Supplement.
Solubility and form
Powders and capsules are common. Powders mix into drinks or food; capsules are convenient for travel. Soluble fibers dissolve and are generally easier to mix; insoluble fibers contribute bulk but are less commonly used as isolated prebiotic supplements.
Types of prebiotic fibers
Inulin and fructooligosaccharides (FOS): Widely used, found in many plants. Strongly fermentable and effective at increasing bifidobacteria and SCFA production. Can cause gas and bloating if increased rapidly.
Galactooligosaccharides (GOS): Well-tolerated by many and selectively feed bifidobacteria; often used for gut-brain and immune-support aims.
Resistant starch and certain non-starch polysaccharides (NSP): Slower-fermenting and may preferentially support butyrate producers; NSPs in cruciferous vegetables can also act against certain harmful bacteria.
Partially fermentable or mixed fibers: Give broader microbial substrates with potentially fewer immediate symptoms for sensitive people.
How to start and ramp up safely
Begin low and go slow. Many people start with 1–2 g per day for several days, then increase by 1–2 g every few days until reaching the target (often 5–10 g/day). A sample ramp:
Week 1: 1–2 g/day
Week 2: 3–4 g/day
Week 3: 5–7 g/day, adjust to tolerance
Take with meals and keep fluids up to help the fiber move through the gut.
Bloating, mild gas, and changes in stool are common when increasing prebiotic intake; these often settle over 1–3 weeks. If symptoms are severe or persistent, reduce dose and discuss with a clinician.
Who should be cautious
People with severe gastrointestinal disease, recent bowel surgery, or complex conditions (e.g., suspected SIBO, severe motility disorders) should discuss supplements with their clinician before starting.
Those with sensitive guts or IBS should introduce prebiotics cautiously; some prebiotic fibers are high-FODMAP and may worsen symptoms in sensitive individuals. Working with a dietitian or clinician can help choose a type and dose that balances benefit and tolerance.
Practical shopping checklist
Prioritize a food-first plan; choose a supplement only if needed.
Confirm the product names and active fiber types are clearly listed.
Aim for 5–10 g/day as a typical target; verify serving size and math on the label.
Look for third-party testing seals and straightforward ingredient lists.
Avoid added sugars and unnecessary fillers.
Conclusion
Prebiotic supplements can be a useful tool to support microbial diversity, increase SCFA-producing bacteria, and support gut–brain and metabolic health—especially when whole-food intake is limited. For most people, a broad‑spectrum prebiotic containing inulin/FOS + GOS or a mix of fermentable fibers, taken at a modest dose (5–10 g/day) with gradual titration, offers a practical balance of effectiveness and tolerability. Wherever possible, prioritize prebiotic-rich whole foods first, and choose third‑party tested supplements when you need them. If you have significant gastrointestinal symptoms or complex health conditions, get personalised guidance from a healthcare provider or dietitian.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
The Best Prebiotic Supplements For Your Microbiome
Learn how to think about supplements thoughtfully when intake falls short.

Written by
Mito Team

What are prebiotics, and why they matter
Prebiotics are specific types of dietary fiber that resist digestion in the small intestine and reach the colon, where they serve as food for beneficial gut microbes. When these microbes ferment prebiotic fibers they produce short-chain fatty acids (SCFAs) such as butyrate, which help fuel colon cells, reduce inflammation, support the gut barrier, and influence metabolism and the brain through the gut–brain axis. Regular intake of prebiotic fiber supports microbial diversity, increases SCFA-producing bacteria, and is associated with lower risk factors for conditions like high cholesterol, blood sugar dysregulation, and some types of colorectal disease.
Whole foods first
The simplest, safest approach is to get prebiotic fibers from whole plant foods. Whole foods bring fiber together with vitamins, minerals, polyphenols and other nutrients that support overall health and the microbiome. Examples of prebiotic-rich foods include:
Chicory root, Jerusalem artichoke, onions, garlic, leeks, asparagus (inulin and FOS)
Legumes and some dairy-derived products (GOS or galactooligosaccharides in supplement form)
Underripe bananas and plantains, broccoli and other cruciferous vegetables (non-starch polysaccharides that can discourage harmful bacteria)
Many people benefit from raising total fiber intake toward common targets around 30 g/day; some populations with high microbial diversity consume 40–50 g/day. When access to a varied, plant-rich diet is limited (travel, restricted food choices, or certain clinical situations), a prebiotic supplement can be a practical, evidence-informed addition.
When should you supplement?
Use a supplement if you:
Struggle to reach prebiotic-rich foods regularly
Need

a targeted dose for a specific goal (e.g., increase bifidobacteria or SCFA production)
Have dietary restrictions, long travel, or limited options
Are working with a clinician to modify the microbiome for a health condition
How to choose the best prebiotic supplement
Look for these features:
Broad-spectrum formulation or single-fiber match to your goals
Broad-spectrum blends (inulin + FOS + GOS + other fermentable fibers) feed a wider range of beneficial microbes and are a good general choice for increasing diversity and SCFA production.
Single fibers (e.g., GOS alone) can be useful if you or your clinician want a targeted effect or you have sensitivity to other fibers.
Clear, realistic dosing
Effective supplement doses typically fall in the 5–10 g/day range. Many products list amounts per serving; choose one that matches your plan and be prepared to adjust.
Purity and additives
Prefer products with minimal added sugars, fillers, or unnecessary flavorings.
Third-party testing and accurate labeling
Some supplements have been shown to contain less active ingredient than listed. Choosing products that have been third‑party tested for content and purity reduces that risk. Examples of third-party tested options include Hyperbiotics Prebiotic, InnovixLabs Broad Spectrum Prebiotic Fiber, and Benefiber Prebiotic Fiber Supplement.
Solubility and form
Powders and capsules are common. Powders mix into drinks or food; capsules are convenient for travel. Soluble fibers dissolve and are generally easier to mix; insoluble fibers contribute bulk but are less commonly used as isolated prebiotic supplements.
Types of prebiotic fibers
Inulin and fructooligosaccharides (FOS): Widely used, found in many plants. Strongly fermentable and effective at increasing bifidobacteria and SCFA production. Can cause gas and bloating if increased rapidly.
Galactooligosaccharides (GOS): Well-tolerated by many and selectively feed bifidobacteria; often used for gut-brain and immune-support aims.
Resistant starch and certain non-starch polysaccharides (NSP): Slower-fermenting and may preferentially support butyrate producers; NSPs in cruciferous vegetables can also act against certain harmful bacteria.
Partially fermentable or mixed fibers: Give broader microbial substrates with potentially fewer immediate symptoms for sensitive people.
How to start and ramp up safely
Begin low and go slow. Many people start with 1–2 g per day for several days, then increase by 1–2 g every few days until reaching the target (often 5–10 g/day). A sample ramp:
Week 1: 1–2 g/day
Week 2: 3–4 g/day
Week 3: 5–7 g/day, adjust to tolerance
Take with meals and keep fluids up to help the fiber move through the gut.
Bloating, mild gas, and changes in stool are common when increasing prebiotic intake; these often settle over 1–3 weeks. If symptoms are severe or persistent, reduce dose and discuss with a clinician.
Who should be cautious
People with severe gastrointestinal disease, recent bowel surgery, or complex conditions (e.g., suspected SIBO, severe motility disorders) should discuss supplements with their clinician before starting.
Those with sensitive guts or IBS should introduce prebiotics cautiously; some prebiotic fibers are high-FODMAP and may worsen symptoms in sensitive individuals. Working with a dietitian or clinician can help choose a type and dose that balances benefit and tolerance.
Practical shopping checklist
Prioritize a food-first plan; choose a supplement only if needed.
Confirm the product names and active fiber types are clearly listed.
Aim for 5–10 g/day as a typical target; verify serving size and math on the label.
Look for third-party testing seals and straightforward ingredient lists.
Avoid added sugars and unnecessary fillers.
Conclusion
Prebiotic supplements can be a useful tool to support microbial diversity, increase SCFA-producing bacteria, and support gut–brain and metabolic health—especially when whole-food intake is limited. For most people, a broad‑spectrum prebiotic containing inulin/FOS + GOS or a mix of fermentable fibers, taken at a modest dose (5–10 g/day) with gradual titration, offers a practical balance of effectiveness and tolerability. Wherever possible, prioritize prebiotic-rich whole foods first, and choose third‑party tested supplements when you need them. If you have significant gastrointestinal symptoms or complex health conditions, get personalised guidance from a healthcare provider or dietitian.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
The Best Prebiotic Supplements For Your Microbiome
Learn how to think about supplements thoughtfully when intake falls short.

Written by
Mito Team

What are prebiotics, and why they matter
Prebiotics are specific types of dietary fiber that resist digestion in the small intestine and reach the colon, where they serve as food for beneficial gut microbes. When these microbes ferment prebiotic fibers they produce short-chain fatty acids (SCFAs) such as butyrate, which help fuel colon cells, reduce inflammation, support the gut barrier, and influence metabolism and the brain through the gut–brain axis. Regular intake of prebiotic fiber supports microbial diversity, increases SCFA-producing bacteria, and is associated with lower risk factors for conditions like high cholesterol, blood sugar dysregulation, and some types of colorectal disease.
Whole foods first
The simplest, safest approach is to get prebiotic fibers from whole plant foods. Whole foods bring fiber together with vitamins, minerals, polyphenols and other nutrients that support overall health and the microbiome. Examples of prebiotic-rich foods include:
Chicory root, Jerusalem artichoke, onions, garlic, leeks, asparagus (inulin and FOS)
Legumes and some dairy-derived products (GOS or galactooligosaccharides in supplement form)
Underripe bananas and plantains, broccoli and other cruciferous vegetables (non-starch polysaccharides that can discourage harmful bacteria)
Many people benefit from raising total fiber intake toward common targets around 30 g/day; some populations with high microbial diversity consume 40–50 g/day. When access to a varied, plant-rich diet is limited (travel, restricted food choices, or certain clinical situations), a prebiotic supplement can be a practical, evidence-informed addition.
When should you supplement?
Use a supplement if you:
Struggle to reach prebiotic-rich foods regularly
Need

a targeted dose for a specific goal (e.g., increase bifidobacteria or SCFA production)
Have dietary restrictions, long travel, or limited options
Are working with a clinician to modify the microbiome for a health condition
How to choose the best prebiotic supplement
Look for these features:
Broad-spectrum formulation or single-fiber match to your goals
Broad-spectrum blends (inulin + FOS + GOS + other fermentable fibers) feed a wider range of beneficial microbes and are a good general choice for increasing diversity and SCFA production.
Single fibers (e.g., GOS alone) can be useful if you or your clinician want a targeted effect or you have sensitivity to other fibers.
Clear, realistic dosing
Effective supplement doses typically fall in the 5–10 g/day range. Many products list amounts per serving; choose one that matches your plan and be prepared to adjust.
Purity and additives
Prefer products with minimal added sugars, fillers, or unnecessary flavorings.
Third-party testing and accurate labeling
Some supplements have been shown to contain less active ingredient than listed. Choosing products that have been third‑party tested for content and purity reduces that risk. Examples of third-party tested options include Hyperbiotics Prebiotic, InnovixLabs Broad Spectrum Prebiotic Fiber, and Benefiber Prebiotic Fiber Supplement.
Solubility and form
Powders and capsules are common. Powders mix into drinks or food; capsules are convenient for travel. Soluble fibers dissolve and are generally easier to mix; insoluble fibers contribute bulk but are less commonly used as isolated prebiotic supplements.
Types of prebiotic fibers
Inulin and fructooligosaccharides (FOS): Widely used, found in many plants. Strongly fermentable and effective at increasing bifidobacteria and SCFA production. Can cause gas and bloating if increased rapidly.
Galactooligosaccharides (GOS): Well-tolerated by many and selectively feed bifidobacteria; often used for gut-brain and immune-support aims.
Resistant starch and certain non-starch polysaccharides (NSP): Slower-fermenting and may preferentially support butyrate producers; NSPs in cruciferous vegetables can also act against certain harmful bacteria.
Partially fermentable or mixed fibers: Give broader microbial substrates with potentially fewer immediate symptoms for sensitive people.
How to start and ramp up safely
Begin low and go slow. Many people start with 1–2 g per day for several days, then increase by 1–2 g every few days until reaching the target (often 5–10 g/day). A sample ramp:
Week 1: 1–2 g/day
Week 2: 3–4 g/day
Week 3: 5–7 g/day, adjust to tolerance
Take with meals and keep fluids up to help the fiber move through the gut.
Bloating, mild gas, and changes in stool are common when increasing prebiotic intake; these often settle over 1–3 weeks. If symptoms are severe or persistent, reduce dose and discuss with a clinician.
Who should be cautious
People with severe gastrointestinal disease, recent bowel surgery, or complex conditions (e.g., suspected SIBO, severe motility disorders) should discuss supplements with their clinician before starting.
Those with sensitive guts or IBS should introduce prebiotics cautiously; some prebiotic fibers are high-FODMAP and may worsen symptoms in sensitive individuals. Working with a dietitian or clinician can help choose a type and dose that balances benefit and tolerance.
Practical shopping checklist
Prioritize a food-first plan; choose a supplement only if needed.
Confirm the product names and active fiber types are clearly listed.
Aim for 5–10 g/day as a typical target; verify serving size and math on the label.
Look for third-party testing seals and straightforward ingredient lists.
Avoid added sugars and unnecessary fillers.
Conclusion
Prebiotic supplements can be a useful tool to support microbial diversity, increase SCFA-producing bacteria, and support gut–brain and metabolic health—especially when whole-food intake is limited. For most people, a broad‑spectrum prebiotic containing inulin/FOS + GOS or a mix of fermentable fibers, taken at a modest dose (5–10 g/day) with gradual titration, offers a practical balance of effectiveness and tolerability. Wherever possible, prioritize prebiotic-rich whole foods first, and choose third‑party tested supplements when you need them. If you have significant gastrointestinal symptoms or complex health conditions, get personalised guidance from a healthcare provider or dietitian.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
The Best Prebiotic Supplements For Your Microbiome
Learn how to think about supplements thoughtfully when intake falls short.

Written by
Mito Team

What are prebiotics, and why they matter
Prebiotics are specific types of dietary fiber that resist digestion in the small intestine and reach the colon, where they serve as food for beneficial gut microbes. When these microbes ferment prebiotic fibers they produce short-chain fatty acids (SCFAs) such as butyrate, which help fuel colon cells, reduce inflammation, support the gut barrier, and influence metabolism and the brain through the gut–brain axis. Regular intake of prebiotic fiber supports microbial diversity, increases SCFA-producing bacteria, and is associated with lower risk factors for conditions like high cholesterol, blood sugar dysregulation, and some types of colorectal disease.
Whole foods first
The simplest, safest approach is to get prebiotic fibers from whole plant foods. Whole foods bring fiber together with vitamins, minerals, polyphenols and other nutrients that support overall health and the microbiome. Examples of prebiotic-rich foods include:
Chicory root, Jerusalem artichoke, onions, garlic, leeks, asparagus (inulin and FOS)
Legumes and some dairy-derived products (GOS or galactooligosaccharides in supplement form)
Underripe bananas and plantains, broccoli and other cruciferous vegetables (non-starch polysaccharides that can discourage harmful bacteria)
Many people benefit from raising total fiber intake toward common targets around 30 g/day; some populations with high microbial diversity consume 40–50 g/day. When access to a varied, plant-rich diet is limited (travel, restricted food choices, or certain clinical situations), a prebiotic supplement can be a practical, evidence-informed addition.
When should you supplement?
Use a supplement if you:
Struggle to reach prebiotic-rich foods regularly
Need

a targeted dose for a specific goal (e.g., increase bifidobacteria or SCFA production)
Have dietary restrictions, long travel, or limited options
Are working with a clinician to modify the microbiome for a health condition
How to choose the best prebiotic supplement
Look for these features:
Broad-spectrum formulation or single-fiber match to your goals
Broad-spectrum blends (inulin + FOS + GOS + other fermentable fibers) feed a wider range of beneficial microbes and are a good general choice for increasing diversity and SCFA production.
Single fibers (e.g., GOS alone) can be useful if you or your clinician want a targeted effect or you have sensitivity to other fibers.
Clear, realistic dosing
Effective supplement doses typically fall in the 5–10 g/day range. Many products list amounts per serving; choose one that matches your plan and be prepared to adjust.
Purity and additives
Prefer products with minimal added sugars, fillers, or unnecessary flavorings.
Third-party testing and accurate labeling
Some supplements have been shown to contain less active ingredient than listed. Choosing products that have been third‑party tested for content and purity reduces that risk. Examples of third-party tested options include Hyperbiotics Prebiotic, InnovixLabs Broad Spectrum Prebiotic Fiber, and Benefiber Prebiotic Fiber Supplement.
Solubility and form
Powders and capsules are common. Powders mix into drinks or food; capsules are convenient for travel. Soluble fibers dissolve and are generally easier to mix; insoluble fibers contribute bulk but are less commonly used as isolated prebiotic supplements.
Types of prebiotic fibers
Inulin and fructooligosaccharides (FOS): Widely used, found in many plants. Strongly fermentable and effective at increasing bifidobacteria and SCFA production. Can cause gas and bloating if increased rapidly.
Galactooligosaccharides (GOS): Well-tolerated by many and selectively feed bifidobacteria; often used for gut-brain and immune-support aims.
Resistant starch and certain non-starch polysaccharides (NSP): Slower-fermenting and may preferentially support butyrate producers; NSPs in cruciferous vegetables can also act against certain harmful bacteria.
Partially fermentable or mixed fibers: Give broader microbial substrates with potentially fewer immediate symptoms for sensitive people.
How to start and ramp up safely
Begin low and go slow. Many people start with 1–2 g per day for several days, then increase by 1–2 g every few days until reaching the target (often 5–10 g/day). A sample ramp:
Week 1: 1–2 g/day
Week 2: 3–4 g/day
Week 3: 5–7 g/day, adjust to tolerance
Take with meals and keep fluids up to help the fiber move through the gut.
Bloating, mild gas, and changes in stool are common when increasing prebiotic intake; these often settle over 1–3 weeks. If symptoms are severe or persistent, reduce dose and discuss with a clinician.
Who should be cautious
People with severe gastrointestinal disease, recent bowel surgery, or complex conditions (e.g., suspected SIBO, severe motility disorders) should discuss supplements with their clinician before starting.
Those with sensitive guts or IBS should introduce prebiotics cautiously; some prebiotic fibers are high-FODMAP and may worsen symptoms in sensitive individuals. Working with a dietitian or clinician can help choose a type and dose that balances benefit and tolerance.
Practical shopping checklist
Prioritize a food-first plan; choose a supplement only if needed.
Confirm the product names and active fiber types are clearly listed.
Aim for 5–10 g/day as a typical target; verify serving size and math on the label.
Look for third-party testing seals and straightforward ingredient lists.
Avoid added sugars and unnecessary fillers.
Conclusion
Prebiotic supplements can be a useful tool to support microbial diversity, increase SCFA-producing bacteria, and support gut–brain and metabolic health—especially when whole-food intake is limited. For most people, a broad‑spectrum prebiotic containing inulin/FOS + GOS or a mix of fermentable fibers, taken at a modest dose (5–10 g/day) with gradual titration, offers a practical balance of effectiveness and tolerability. Wherever possible, prioritize prebiotic-rich whole foods first, and choose third‑party tested supplements when you need them. If you have significant gastrointestinal symptoms or complex health conditions, get personalised guidance from a healthcare provider or dietitian.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Recently published
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
What's included
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
What's included
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
What's included
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
What's included
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)



