Mito Health: Helping you live healthier, longer.
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The Mineral That Does More: Magnesium’s Role in Healthspan
Magnesium plays a role in many core processes throughout the body, which is why it comes up so often in health conversations. Explore its benefits.

Written by
Mito Team

What is magnesium
Magnesium is an essential mineral that your body needs to function well. It’s involved in more than 300 biochemical reactions, helping power metabolism, control muscles and nerves, support heart and bone health, and regulate blood pressure. Most people get magnesium from food, but many don’t reach recommended intakes every day — and supplements can be helpful in certain situations.
Why magnesium matters
Energy and metabolism: Magnesium is a key ingredient in processes that turn food into usable energy. It helps enzymes work efficiently.
Muscle and nerve function: Magnesium helps muscles relax after contraction and supports normal nerve signaling. This is why low magnesium can show up as muscle cramps or twitches.
Heart health and blood pressure: Magnesium helps maintain a steady heartbeat and supports healthy blood pressure regulation.
Bone health: Magnesium works with calcium and vitamin D to support bone structure and strength.
Blood sugar control: Adequate magnesium supports healthy glucose metabolism and insulin function.
Brain and sleep: Magnesium has roles in nervous system regulation and may help with sleep quality and some aspects of cognitive function.
Symptom relief: Maintaining healthy magnesium levels can reduce the intensity of menstrual pain, muscle cramps, and certain types of headaches.
How to tell if you might be low
A standard blood magnesium test is commonly used, but it doesn’t always reflect total body magnesium since most of it sits inside cells and in bone. Signs that magnesium may be low include frequent muscle cramps, persistent fatigue, irregular heartbeat, numbness or tingling, and recurring headaches or migraines. If symptoms are present or a healthcare professional suspects deficiency, they can advise on further testing or a trial of dietary and supplemental changes.
Diet first — foods rich in magnesium
Aim to get most of your magnesium from a varied, plant-rich diet. Good sources include:
Leafy green vegetables (spinach, Swiss chard)
Nuts and seeds (almonds, pumpkin seeds)
Legumes (beans, lentils)
Whole grains
Tofu and other soy products
Dark chocolate
Recommended intake
Adults are generally advised to meet recommended dietary intakes — about 420 mg daily for men and 320 mg daily for women. Many people don’t reach these levels through diet alone. When a supplement is used to support an already healthy, plant-rich diet, lower supplemental doses in the 300–350 mg range are often sufficient.
If supplementation is needed:
Consider the total magnesium you get from both food and supplement.
Divide larger doses across the day to reduce the chance of stomach upset.
Taking magnesium with a meal often reduces digestive side effects.
Evening dosing can be helpful for sleep or muscle relaxation for some people.
Which magnesium is suitable?
Magnesium appears in many forms. They differ in how well the body absorbs them and how likely they are to cause loose stools. Common choices:
Magnesium chloride: Well absorbed and less likely to cause diarrhea; a good general option.
Magnesium bisglycinate (glycinate): Well absorbed, gentle on the stomach, and low risk of laxative effects.
Magnesium glycerophosphate: Also well tolerated with fewer bowel effects.
Magnesium citrate, gluconate, lactate, aspartate: Generally well absorbed and good value, but higher doses can cause diarrhea in some people.
Magnesium oxide: Often the cheapest, but less well absorbed and more likely to cause stomach upset and diarrhea — not ideal unless managing infrequent bowel movements or constipation.
Magnesium L‑threonate: More expensive and usually provides lower elemental magnesium per dose. It crosses into the brain and is chosen by some for potential cognitive and sleep benefits, but it’s less effective for replenishing whole-body magnesium stores.
Recommended forms
If taking a supplement, prefer forms that absorb well and minimize laxative effects, such as magnesium chloride or bisglycinate.
Magnesium citrate offers good value but be aware of possible diarrhea at higher doses.
Avoid magnesium oxide unless you have a specific reason (for example, if you need its laxative effect).
Some people choose magnesium L‑threonate specifically for cognitive or sleep reasons, recognizing it may not be the best choice for rebuilding overall magnesium stores.
Examples of third-party tested options are available from established supplement brands; look for products tested by independent labs for purity and potency.
Safety and interactions
Too much magnesium from supplements can cause diarrhea and stomach cramps; bowel tolerance is a practical sign that the dose is too high.
People with impaired kidney function should be cautious because the kidneys remove excess magnesium; supplementation in these cases should only be done under medical supervision.
Magnesium can interact with certain medications (for example, some antibiotics, bisphosphonates, and diuretics). If you take regular prescription medications, check with a healthcare professional before starting a supplement.
Pregnant or breastfeeding people should discuss magnesium dosing with their care provider.
When supplementation makes sense
Supplementing makes the most sense when dietary intake is insufficient, when symptoms suggest low magnesium, or when a healthcare professional recommends it for conditions like high blood pressure, muscle cramps, certain menstrual symptoms, or to support glucose control and vitamin D function. For many people aiming to complement a healthy, plant-rich diet, supplemental doses around 300–350 mg of elemental magnesium are commonly used.
Conclusion
Magnesium is a vital mineral for energy, muscle and nerve function, heart and bone health, blood sugar regulation, and more. Prioritize magnesium-rich foods, and consider a supplement when dietary intake is inadequate or when specific health goals call for extra support. Choose a well-absorbed form (chloride or bisglycinate are good starting points), watch for digestive side effects, and check with a healthcare professional if you have kidney problems or take regular medications.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
The Mineral That Does More: Magnesium’s Role in Healthspan
Magnesium plays a role in many core processes throughout the body, which is why it comes up so often in health conversations. Explore its benefits.

Written by
Mito Team

What is magnesium
Magnesium is an essential mineral that your body needs to function well. It’s involved in more than 300 biochemical reactions, helping power metabolism, control muscles and nerves, support heart and bone health, and regulate blood pressure. Most people get magnesium from food, but many don’t reach recommended intakes every day — and supplements can be helpful in certain situations.
Why magnesium matters
Energy and metabolism: Magnesium is a key ingredient in processes that turn food into usable energy. It helps enzymes work efficiently.
Muscle and nerve function: Magnesium helps muscles relax after contraction and supports normal nerve signaling. This is why low magnesium can show up as muscle cramps or twitches.
Heart health and blood pressure: Magnesium helps maintain a steady heartbeat and supports healthy blood pressure regulation.
Bone health: Magnesium works with calcium and vitamin D to support bone structure and strength.
Blood sugar control: Adequate magnesium supports healthy glucose metabolism and insulin function.
Brain and sleep: Magnesium has roles in nervous system regulation and may help with sleep quality and some aspects of cognitive function.
Symptom relief: Maintaining healthy magnesium levels can reduce the intensity of menstrual pain, muscle cramps, and certain types of headaches.
How to tell if you might be low
A standard blood magnesium test is commonly used, but it doesn’t always reflect total body magnesium since most of it sits inside cells and in bone. Signs that magnesium may be low include frequent muscle cramps, persistent fatigue, irregular heartbeat, numbness or tingling, and recurring headaches or migraines. If symptoms are present or a healthcare professional suspects deficiency, they can advise on further testing or a trial of dietary and supplemental changes.
Diet first — foods rich in magnesium
Aim to get most of your magnesium from a varied, plant-rich diet. Good sources include:
Leafy green vegetables (spinach, Swiss chard)
Nuts and seeds (almonds, pumpkin seeds)
Legumes (beans, lentils)
Whole grains
Tofu and other soy products
Dark chocolate
Recommended intake
Adults are generally advised to meet recommended dietary intakes — about 420 mg daily for men and 320 mg daily for women. Many people don’t reach these levels through diet alone. When a supplement is used to support an already healthy, plant-rich diet, lower supplemental doses in the 300–350 mg range are often sufficient.
If supplementation is needed:
Consider the total magnesium you get from both food and supplement.
Divide larger doses across the day to reduce the chance of stomach upset.
Taking magnesium with a meal often reduces digestive side effects.
Evening dosing can be helpful for sleep or muscle relaxation for some people.
Which magnesium is suitable?
Magnesium appears in many forms. They differ in how well the body absorbs them and how likely they are to cause loose stools. Common choices:
Magnesium chloride: Well absorbed and less likely to cause diarrhea; a good general option.
Magnesium bisglycinate (glycinate): Well absorbed, gentle on the stomach, and low risk of laxative effects.
Magnesium glycerophosphate: Also well tolerated with fewer bowel effects.
Magnesium citrate, gluconate, lactate, aspartate: Generally well absorbed and good value, but higher doses can cause diarrhea in some people.
Magnesium oxide: Often the cheapest, but less well absorbed and more likely to cause stomach upset and diarrhea — not ideal unless managing infrequent bowel movements or constipation.
Magnesium L‑threonate: More expensive and usually provides lower elemental magnesium per dose. It crosses into the brain and is chosen by some for potential cognitive and sleep benefits, but it’s less effective for replenishing whole-body magnesium stores.
Recommended forms
If taking a supplement, prefer forms that absorb well and minimize laxative effects, such as magnesium chloride or bisglycinate.
Magnesium citrate offers good value but be aware of possible diarrhea at higher doses.
Avoid magnesium oxide unless you have a specific reason (for example, if you need its laxative effect).
Some people choose magnesium L‑threonate specifically for cognitive or sleep reasons, recognizing it may not be the best choice for rebuilding overall magnesium stores.
Examples of third-party tested options are available from established supplement brands; look for products tested by independent labs for purity and potency.
Safety and interactions
Too much magnesium from supplements can cause diarrhea and stomach cramps; bowel tolerance is a practical sign that the dose is too high.
People with impaired kidney function should be cautious because the kidneys remove excess magnesium; supplementation in these cases should only be done under medical supervision.
Magnesium can interact with certain medications (for example, some antibiotics, bisphosphonates, and diuretics). If you take regular prescription medications, check with a healthcare professional before starting a supplement.
Pregnant or breastfeeding people should discuss magnesium dosing with their care provider.
When supplementation makes sense
Supplementing makes the most sense when dietary intake is insufficient, when symptoms suggest low magnesium, or when a healthcare professional recommends it for conditions like high blood pressure, muscle cramps, certain menstrual symptoms, or to support glucose control and vitamin D function. For many people aiming to complement a healthy, plant-rich diet, supplemental doses around 300–350 mg of elemental magnesium are commonly used.
Conclusion
Magnesium is a vital mineral for energy, muscle and nerve function, heart and bone health, blood sugar regulation, and more. Prioritize magnesium-rich foods, and consider a supplement when dietary intake is inadequate or when specific health goals call for extra support. Choose a well-absorbed form (chloride or bisglycinate are good starting points), watch for digestive side effects, and check with a healthcare professional if you have kidney problems or take regular medications.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
The Mineral That Does More: Magnesium’s Role in Healthspan
Magnesium plays a role in many core processes throughout the body, which is why it comes up so often in health conversations. Explore its benefits.

Written by
Mito Team

What is magnesium
Magnesium is an essential mineral that your body needs to function well. It’s involved in more than 300 biochemical reactions, helping power metabolism, control muscles and nerves, support heart and bone health, and regulate blood pressure. Most people get magnesium from food, but many don’t reach recommended intakes every day — and supplements can be helpful in certain situations.
Why magnesium matters
Energy and metabolism: Magnesium is a key ingredient in processes that turn food into usable energy. It helps enzymes work efficiently.
Muscle and nerve function: Magnesium helps muscles relax after contraction and supports normal nerve signaling. This is why low magnesium can show up as muscle cramps or twitches.
Heart health and blood pressure: Magnesium helps maintain a steady heartbeat and supports healthy blood pressure regulation.
Bone health: Magnesium works with calcium and vitamin D to support bone structure and strength.
Blood sugar control: Adequate magnesium supports healthy glucose metabolism and insulin function.
Brain and sleep: Magnesium has roles in nervous system regulation and may help with sleep quality and some aspects of cognitive function.
Symptom relief: Maintaining healthy magnesium levels can reduce the intensity of menstrual pain, muscle cramps, and certain types of headaches.
How to tell if you might be low
A standard blood magnesium test is commonly used, but it doesn’t always reflect total body magnesium since most of it sits inside cells and in bone. Signs that magnesium may be low include frequent muscle cramps, persistent fatigue, irregular heartbeat, numbness or tingling, and recurring headaches or migraines. If symptoms are present or a healthcare professional suspects deficiency, they can advise on further testing or a trial of dietary and supplemental changes.
Diet first — foods rich in magnesium
Aim to get most of your magnesium from a varied, plant-rich diet. Good sources include:
Leafy green vegetables (spinach, Swiss chard)
Nuts and seeds (almonds, pumpkin seeds)
Legumes (beans, lentils)
Whole grains
Tofu and other soy products
Dark chocolate
Recommended intake
Adults are generally advised to meet recommended dietary intakes — about 420 mg daily for men and 320 mg daily for women. Many people don’t reach these levels through diet alone. When a supplement is used to support an already healthy, plant-rich diet, lower supplemental doses in the 300–350 mg range are often sufficient.
If supplementation is needed:
Consider the total magnesium you get from both food and supplement.
Divide larger doses across the day to reduce the chance of stomach upset.
Taking magnesium with a meal often reduces digestive side effects.
Evening dosing can be helpful for sleep or muscle relaxation for some people.
Which magnesium is suitable?
Magnesium appears in many forms. They differ in how well the body absorbs them and how likely they are to cause loose stools. Common choices:
Magnesium chloride: Well absorbed and less likely to cause diarrhea; a good general option.
Magnesium bisglycinate (glycinate): Well absorbed, gentle on the stomach, and low risk of laxative effects.
Magnesium glycerophosphate: Also well tolerated with fewer bowel effects.
Magnesium citrate, gluconate, lactate, aspartate: Generally well absorbed and good value, but higher doses can cause diarrhea in some people.
Magnesium oxide: Often the cheapest, but less well absorbed and more likely to cause stomach upset and diarrhea — not ideal unless managing infrequent bowel movements or constipation.
Magnesium L‑threonate: More expensive and usually provides lower elemental magnesium per dose. It crosses into the brain and is chosen by some for potential cognitive and sleep benefits, but it’s less effective for replenishing whole-body magnesium stores.
Recommended forms
If taking a supplement, prefer forms that absorb well and minimize laxative effects, such as magnesium chloride or bisglycinate.
Magnesium citrate offers good value but be aware of possible diarrhea at higher doses.
Avoid magnesium oxide unless you have a specific reason (for example, if you need its laxative effect).
Some people choose magnesium L‑threonate specifically for cognitive or sleep reasons, recognizing it may not be the best choice for rebuilding overall magnesium stores.
Examples of third-party tested options are available from established supplement brands; look for products tested by independent labs for purity and potency.
Safety and interactions
Too much magnesium from supplements can cause diarrhea and stomach cramps; bowel tolerance is a practical sign that the dose is too high.
People with impaired kidney function should be cautious because the kidneys remove excess magnesium; supplementation in these cases should only be done under medical supervision.
Magnesium can interact with certain medications (for example, some antibiotics, bisphosphonates, and diuretics). If you take regular prescription medications, check with a healthcare professional before starting a supplement.
Pregnant or breastfeeding people should discuss magnesium dosing with their care provider.
When supplementation makes sense
Supplementing makes the most sense when dietary intake is insufficient, when symptoms suggest low magnesium, or when a healthcare professional recommends it for conditions like high blood pressure, muscle cramps, certain menstrual symptoms, or to support glucose control and vitamin D function. For many people aiming to complement a healthy, plant-rich diet, supplemental doses around 300–350 mg of elemental magnesium are commonly used.
Conclusion
Magnesium is a vital mineral for energy, muscle and nerve function, heart and bone health, blood sugar regulation, and more. Prioritize magnesium-rich foods, and consider a supplement when dietary intake is inadequate or when specific health goals call for extra support. Choose a well-absorbed form (chloride or bisglycinate are good starting points), watch for digestive side effects, and check with a healthcare professional if you have kidney problems or take regular medications.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
The Mineral That Does More: Magnesium’s Role in Healthspan
Magnesium plays a role in many core processes throughout the body, which is why it comes up so often in health conversations. Explore its benefits.

Written by
Mito Team

What is magnesium
Magnesium is an essential mineral that your body needs to function well. It’s involved in more than 300 biochemical reactions, helping power metabolism, control muscles and nerves, support heart and bone health, and regulate blood pressure. Most people get magnesium from food, but many don’t reach recommended intakes every day — and supplements can be helpful in certain situations.
Why magnesium matters
Energy and metabolism: Magnesium is a key ingredient in processes that turn food into usable energy. It helps enzymes work efficiently.
Muscle and nerve function: Magnesium helps muscles relax after contraction and supports normal nerve signaling. This is why low magnesium can show up as muscle cramps or twitches.
Heart health and blood pressure: Magnesium helps maintain a steady heartbeat and supports healthy blood pressure regulation.
Bone health: Magnesium works with calcium and vitamin D to support bone structure and strength.
Blood sugar control: Adequate magnesium supports healthy glucose metabolism and insulin function.
Brain and sleep: Magnesium has roles in nervous system regulation and may help with sleep quality and some aspects of cognitive function.
Symptom relief: Maintaining healthy magnesium levels can reduce the intensity of menstrual pain, muscle cramps, and certain types of headaches.
How to tell if you might be low
A standard blood magnesium test is commonly used, but it doesn’t always reflect total body magnesium since most of it sits inside cells and in bone. Signs that magnesium may be low include frequent muscle cramps, persistent fatigue, irregular heartbeat, numbness or tingling, and recurring headaches or migraines. If symptoms are present or a healthcare professional suspects deficiency, they can advise on further testing or a trial of dietary and supplemental changes.
Diet first — foods rich in magnesium
Aim to get most of your magnesium from a varied, plant-rich diet. Good sources include:
Leafy green vegetables (spinach, Swiss chard)
Nuts and seeds (almonds, pumpkin seeds)
Legumes (beans, lentils)
Whole grains
Tofu and other soy products
Dark chocolate
Recommended intake
Adults are generally advised to meet recommended dietary intakes — about 420 mg daily for men and 320 mg daily for women. Many people don’t reach these levels through diet alone. When a supplement is used to support an already healthy, plant-rich diet, lower supplemental doses in the 300–350 mg range are often sufficient.
If supplementation is needed:
Consider the total magnesium you get from both food and supplement.
Divide larger doses across the day to reduce the chance of stomach upset.
Taking magnesium with a meal often reduces digestive side effects.
Evening dosing can be helpful for sleep or muscle relaxation for some people.
Which magnesium is suitable?
Magnesium appears in many forms. They differ in how well the body absorbs them and how likely they are to cause loose stools. Common choices:
Magnesium chloride: Well absorbed and less likely to cause diarrhea; a good general option.
Magnesium bisglycinate (glycinate): Well absorbed, gentle on the stomach, and low risk of laxative effects.
Magnesium glycerophosphate: Also well tolerated with fewer bowel effects.
Magnesium citrate, gluconate, lactate, aspartate: Generally well absorbed and good value, but higher doses can cause diarrhea in some people.
Magnesium oxide: Often the cheapest, but less well absorbed and more likely to cause stomach upset and diarrhea — not ideal unless managing infrequent bowel movements or constipation.
Magnesium L‑threonate: More expensive and usually provides lower elemental magnesium per dose. It crosses into the brain and is chosen by some for potential cognitive and sleep benefits, but it’s less effective for replenishing whole-body magnesium stores.
Recommended forms
If taking a supplement, prefer forms that absorb well and minimize laxative effects, such as magnesium chloride or bisglycinate.
Magnesium citrate offers good value but be aware of possible diarrhea at higher doses.
Avoid magnesium oxide unless you have a specific reason (for example, if you need its laxative effect).
Some people choose magnesium L‑threonate specifically for cognitive or sleep reasons, recognizing it may not be the best choice for rebuilding overall magnesium stores.
Examples of third-party tested options are available from established supplement brands; look for products tested by independent labs for purity and potency.
Safety and interactions
Too much magnesium from supplements can cause diarrhea and stomach cramps; bowel tolerance is a practical sign that the dose is too high.
People with impaired kidney function should be cautious because the kidneys remove excess magnesium; supplementation in these cases should only be done under medical supervision.
Magnesium can interact with certain medications (for example, some antibiotics, bisphosphonates, and diuretics). If you take regular prescription medications, check with a healthcare professional before starting a supplement.
Pregnant or breastfeeding people should discuss magnesium dosing with their care provider.
When supplementation makes sense
Supplementing makes the most sense when dietary intake is insufficient, when symptoms suggest low magnesium, or when a healthcare professional recommends it for conditions like high blood pressure, muscle cramps, certain menstrual symptoms, or to support glucose control and vitamin D function. For many people aiming to complement a healthy, plant-rich diet, supplemental doses around 300–350 mg of elemental magnesium are commonly used.
Conclusion
Magnesium is a vital mineral for energy, muscle and nerve function, heart and bone health, blood sugar regulation, and more. Prioritize magnesium-rich foods, and consider a supplement when dietary intake is inadequate or when specific health goals call for extra support. Choose a well-absorbed form (chloride or bisglycinate are good starting points), watch for digestive side effects, and check with a healthcare professional if you have kidney problems or take regular medications.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Recently published
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
What's included
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
What's included
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
What's included
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
What's included
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)



