Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Everything You Should Know About Iron Supplements
Iron often comes up in conversations about fatigue and blood health. Explore how iron functions in the body and why understanding iron status matters before supplementing.

Written by
Mito Team

Why iron matters
Iron is an essential mineral your body needs to make hemoglobin, the protein in red blood cells that carries oxygen around the body. Adequate iron supports energy, concentration, immune function and physical performance. When iron is low, people may feel unusually tired, have trouble concentrating or notice reduced physical stamina — and when deficiency progresses to anemia, hemoglobin falls and symptoms become more obvious.
How much iron do people need?
Recommended daily intakes vary by age, sex and life stage. Typical targets are about 8 mg per day for adult men and roughly 18 mg per day for pre‑menopausal, non‑pregnant women. Pregnant people and anyone with ongoing blood loss (for example, heavy menstrual bleeding, gastric bleeding) need more. People who eat only plant foods generally need more dietary iron because iron from plants (non‑heme iron) is absorbed less efficiently than iron from animal foods (heme iron) — commonly estimated around 1.8–2× higher dietary needs for vegetarians.
When to consider supplements
Confirmed deficiency: If blood tests show iron deficiency (low ferritin and/or low hemoglobin), targeted iron replacement is appropriate. In iron deficiency anemia, higher doses are commonly used to restore hemoglobin and iron stores.
Low iron without anemia: People can have low iron stores before anemia develops. Some may benefit from supplementation if they have symptoms such as unexplained fatigue, poor exercise tolerance or decreased concentration and low iron biomarkers.
Higher needs: Pregnancy, frequent blood donation, heavy menstrual loss or conditions that reduce absorption may justify supplement use.
When to avoid: If routine blood tests show normal iron stores, there is usually no benefit to continuing iron supplements. Certain conditions (for example, some genetic blood disorders such as thalassemia) can be associated with increased iron absorption — people with these conditions should generally avoid iron supplements unless they have documented iron deficiency and are being managed by a clinician.
Typical dosing
Maintenance / prevention: For people with mildly low stores or higher risk (for example, vegetarians) but normal hemoglobin, lower doses in the range of about 15–30 mg elemental iron daily are often sufficient when combined with dietary changes.
Replacement for iron deficiency anemia: Doses of 50–100 mg elemental iron once daily are commonly recommended to replace iron and correct anemia. These higher doses are prescribed until iron stores recover and hemoglobin normalizes.
Start low to reduce side effects: Because oral iron commonly causes stomach upset or constipation, it’s sensible for many people to begin at a lower dose and increase as tolerated while improving dietary iron intake at the same time.
Forms of iron
Heme vs non‑heme: Heme iron from animal sources is better absorbed than non‑heme iron from plants.
Iron salts: Common supplement forms include ferrous sulfate, ferrous gluconate and ferrous fumarate. These provide different amounts of elemental iron but are generally effective.
Slow‑release or enteric‑coated formulations: These may reduce gastrointestinal side effects for some people but can also reduce how much iron is absorbed and therefore slow correction of deficiency.
Specialized forms: Some products use iron bound to proteins (for example, iron protein succinylate) and may be easier on the gut for people who have persistent constipation with standard iron salts.
Tips to improve absorption and lower side effects
Take with vitamin C: Vitamin C (for example, a small glass of orange juice) increases absorption of non‑heme iron.
Avoid inhibitors around dosing: Tea, coffee, calcium‑rich foods and some high‑phytate foods can reduce absorption if consumed right with the iron dose. Aim to separate these by an hour or two when possible.
Food trade‑off: Taking iron with food usually reduces stomach upset but can lower absorption. Decide based on tolerance — better absorption on an empty stomach vs better tolerability with food.
Manage constipation and stomach upset: Drink plenty of water, eat a high‑fiber diet, and consider gentle bowel routines. If constipation continues, switching to a different iron form (for example, a protein‑bound form) or discussing a change of preparation with a clinician can help.
Slow‑release caution: If using slow‑release preparations to reduce side effects, be aware they may decrease the amount of iron absorbed and may need longer treatment to replenish stores.
Safety considerations and monitoring
Check before you start: It’s important to know your iron status (ferritin, hemoglobin) before beginning supplements. Taking iron when stores are adequate adds no benefit and may cause harm.
Repeat testing: If you start iron supplements, repeating blood tests — commonly after about three months — helps determine whether the dose is working and whether to continue, increase or stop supplementation.
Avoid long‑term excess: Chronic excess iron can accumulate in organs and, over time, contribute to liver problems, diabetes, joint symptoms and heart issues. This is why testing and follow‑up are important.
Keep away from children: Iron tablets can be dangerous if swallowed by children. Store supplements securely out of reach.
Practical product guidance
Start with dietary approaches (red meat, poultry, fish, beans, lentils, fortified cereals, dark leafy greens) alongside any supplements.
For lower maintenance doses, there are many widely available options in the 15–30 mg range. For higher replacement doses (50–100 mg), there are over‑the‑counter products and prescription tablets. Some manufacturers offer third‑party testing; if you prefer that reassurance, look for brands with independent verification and clear labeling of elemental iron content.
If you experience intolerable side effects, talk with your clinician about changing the dose, switching forms (including protein‑bound iron), or considering prescription options.
Conclusion
Iron is vital for energy and blood health. Supplements are a useful tool when tests show low iron or anemia, but they are not harmless and should be used thoughtfully. Start by confirming your iron status with blood tests, try dietary improvements alongside any supplement, begin with the lowest effective dose for most people, and monitor response with repeat testing. If you have a known blood disorder, complex medical conditions, or persistent side effects, discuss management with your healthcare practitioner to choose the safest and most effective approach.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Everything You Should Know About Iron Supplements
Iron often comes up in conversations about fatigue and blood health. Explore how iron functions in the body and why understanding iron status matters before supplementing.

Written by
Mito Team

Why iron matters
Iron is an essential mineral your body needs to make hemoglobin, the protein in red blood cells that carries oxygen around the body. Adequate iron supports energy, concentration, immune function and physical performance. When iron is low, people may feel unusually tired, have trouble concentrating or notice reduced physical stamina — and when deficiency progresses to anemia, hemoglobin falls and symptoms become more obvious.
How much iron do people need?
Recommended daily intakes vary by age, sex and life stage. Typical targets are about 8 mg per day for adult men and roughly 18 mg per day for pre‑menopausal, non‑pregnant women. Pregnant people and anyone with ongoing blood loss (for example, heavy menstrual bleeding, gastric bleeding) need more. People who eat only plant foods generally need more dietary iron because iron from plants (non‑heme iron) is absorbed less efficiently than iron from animal foods (heme iron) — commonly estimated around 1.8–2× higher dietary needs for vegetarians.
When to consider supplements
Confirmed deficiency: If blood tests show iron deficiency (low ferritin and/or low hemoglobin), targeted iron replacement is appropriate. In iron deficiency anemia, higher doses are commonly used to restore hemoglobin and iron stores.
Low iron without anemia: People can have low iron stores before anemia develops. Some may benefit from supplementation if they have symptoms such as unexplained fatigue, poor exercise tolerance or decreased concentration and low iron biomarkers.
Higher needs: Pregnancy, frequent blood donation, heavy menstrual loss or conditions that reduce absorption may justify supplement use.
When to avoid: If routine blood tests show normal iron stores, there is usually no benefit to continuing iron supplements. Certain conditions (for example, some genetic blood disorders such as thalassemia) can be associated with increased iron absorption — people with these conditions should generally avoid iron supplements unless they have documented iron deficiency and are being managed by a clinician.
Typical dosing
Maintenance / prevention: For people with mildly low stores or higher risk (for example, vegetarians) but normal hemoglobin, lower doses in the range of about 15–30 mg elemental iron daily are often sufficient when combined with dietary changes.
Replacement for iron deficiency anemia: Doses of 50–100 mg elemental iron once daily are commonly recommended to replace iron and correct anemia. These higher doses are prescribed until iron stores recover and hemoglobin normalizes.
Start low to reduce side effects: Because oral iron commonly causes stomach upset or constipation, it’s sensible for many people to begin at a lower dose and increase as tolerated while improving dietary iron intake at the same time.
Forms of iron
Heme vs non‑heme: Heme iron from animal sources is better absorbed than non‑heme iron from plants.
Iron salts: Common supplement forms include ferrous sulfate, ferrous gluconate and ferrous fumarate. These provide different amounts of elemental iron but are generally effective.
Slow‑release or enteric‑coated formulations: These may reduce gastrointestinal side effects for some people but can also reduce how much iron is absorbed and therefore slow correction of deficiency.
Specialized forms: Some products use iron bound to proteins (for example, iron protein succinylate) and may be easier on the gut for people who have persistent constipation with standard iron salts.
Tips to improve absorption and lower side effects
Take with vitamin C: Vitamin C (for example, a small glass of orange juice) increases absorption of non‑heme iron.
Avoid inhibitors around dosing: Tea, coffee, calcium‑rich foods and some high‑phytate foods can reduce absorption if consumed right with the iron dose. Aim to separate these by an hour or two when possible.
Food trade‑off: Taking iron with food usually reduces stomach upset but can lower absorption. Decide based on tolerance — better absorption on an empty stomach vs better tolerability with food.
Manage constipation and stomach upset: Drink plenty of water, eat a high‑fiber diet, and consider gentle bowel routines. If constipation continues, switching to a different iron form (for example, a protein‑bound form) or discussing a change of preparation with a clinician can help.
Slow‑release caution: If using slow‑release preparations to reduce side effects, be aware they may decrease the amount of iron absorbed and may need longer treatment to replenish stores.
Safety considerations and monitoring
Check before you start: It’s important to know your iron status (ferritin, hemoglobin) before beginning supplements. Taking iron when stores are adequate adds no benefit and may cause harm.
Repeat testing: If you start iron supplements, repeating blood tests — commonly after about three months — helps determine whether the dose is working and whether to continue, increase or stop supplementation.
Avoid long‑term excess: Chronic excess iron can accumulate in organs and, over time, contribute to liver problems, diabetes, joint symptoms and heart issues. This is why testing and follow‑up are important.
Keep away from children: Iron tablets can be dangerous if swallowed by children. Store supplements securely out of reach.
Practical product guidance
Start with dietary approaches (red meat, poultry, fish, beans, lentils, fortified cereals, dark leafy greens) alongside any supplements.
For lower maintenance doses, there are many widely available options in the 15–30 mg range. For higher replacement doses (50–100 mg), there are over‑the‑counter products and prescription tablets. Some manufacturers offer third‑party testing; if you prefer that reassurance, look for brands with independent verification and clear labeling of elemental iron content.
If you experience intolerable side effects, talk with your clinician about changing the dose, switching forms (including protein‑bound iron), or considering prescription options.
Conclusion
Iron is vital for energy and blood health. Supplements are a useful tool when tests show low iron or anemia, but they are not harmless and should be used thoughtfully. Start by confirming your iron status with blood tests, try dietary improvements alongside any supplement, begin with the lowest effective dose for most people, and monitor response with repeat testing. If you have a known blood disorder, complex medical conditions, or persistent side effects, discuss management with your healthcare practitioner to choose the safest and most effective approach.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Everything You Should Know About Iron Supplements
Iron often comes up in conversations about fatigue and blood health. Explore how iron functions in the body and why understanding iron status matters before supplementing.

Written by
Mito Team

Why iron matters
Iron is an essential mineral your body needs to make hemoglobin, the protein in red blood cells that carries oxygen around the body. Adequate iron supports energy, concentration, immune function and physical performance. When iron is low, people may feel unusually tired, have trouble concentrating or notice reduced physical stamina — and when deficiency progresses to anemia, hemoglobin falls and symptoms become more obvious.
How much iron do people need?
Recommended daily intakes vary by age, sex and life stage. Typical targets are about 8 mg per day for adult men and roughly 18 mg per day for pre‑menopausal, non‑pregnant women. Pregnant people and anyone with ongoing blood loss (for example, heavy menstrual bleeding, gastric bleeding) need more. People who eat only plant foods generally need more dietary iron because iron from plants (non‑heme iron) is absorbed less efficiently than iron from animal foods (heme iron) — commonly estimated around 1.8–2× higher dietary needs for vegetarians.
When to consider supplements
Confirmed deficiency: If blood tests show iron deficiency (low ferritin and/or low hemoglobin), targeted iron replacement is appropriate. In iron deficiency anemia, higher doses are commonly used to restore hemoglobin and iron stores.
Low iron without anemia: People can have low iron stores before anemia develops. Some may benefit from supplementation if they have symptoms such as unexplained fatigue, poor exercise tolerance or decreased concentration and low iron biomarkers.
Higher needs: Pregnancy, frequent blood donation, heavy menstrual loss or conditions that reduce absorption may justify supplement use.
When to avoid: If routine blood tests show normal iron stores, there is usually no benefit to continuing iron supplements. Certain conditions (for example, some genetic blood disorders such as thalassemia) can be associated with increased iron absorption — people with these conditions should generally avoid iron supplements unless they have documented iron deficiency and are being managed by a clinician.
Typical dosing
Maintenance / prevention: For people with mildly low stores or higher risk (for example, vegetarians) but normal hemoglobin, lower doses in the range of about 15–30 mg elemental iron daily are often sufficient when combined with dietary changes.
Replacement for iron deficiency anemia: Doses of 50–100 mg elemental iron once daily are commonly recommended to replace iron and correct anemia. These higher doses are prescribed until iron stores recover and hemoglobin normalizes.
Start low to reduce side effects: Because oral iron commonly causes stomach upset or constipation, it’s sensible for many people to begin at a lower dose and increase as tolerated while improving dietary iron intake at the same time.
Forms of iron
Heme vs non‑heme: Heme iron from animal sources is better absorbed than non‑heme iron from plants.
Iron salts: Common supplement forms include ferrous sulfate, ferrous gluconate and ferrous fumarate. These provide different amounts of elemental iron but are generally effective.
Slow‑release or enteric‑coated formulations: These may reduce gastrointestinal side effects for some people but can also reduce how much iron is absorbed and therefore slow correction of deficiency.
Specialized forms: Some products use iron bound to proteins (for example, iron protein succinylate) and may be easier on the gut for people who have persistent constipation with standard iron salts.
Tips to improve absorption and lower side effects
Take with vitamin C: Vitamin C (for example, a small glass of orange juice) increases absorption of non‑heme iron.
Avoid inhibitors around dosing: Tea, coffee, calcium‑rich foods and some high‑phytate foods can reduce absorption if consumed right with the iron dose. Aim to separate these by an hour or two when possible.
Food trade‑off: Taking iron with food usually reduces stomach upset but can lower absorption. Decide based on tolerance — better absorption on an empty stomach vs better tolerability with food.
Manage constipation and stomach upset: Drink plenty of water, eat a high‑fiber diet, and consider gentle bowel routines. If constipation continues, switching to a different iron form (for example, a protein‑bound form) or discussing a change of preparation with a clinician can help.
Slow‑release caution: If using slow‑release preparations to reduce side effects, be aware they may decrease the amount of iron absorbed and may need longer treatment to replenish stores.
Safety considerations and monitoring
Check before you start: It’s important to know your iron status (ferritin, hemoglobin) before beginning supplements. Taking iron when stores are adequate adds no benefit and may cause harm.
Repeat testing: If you start iron supplements, repeating blood tests — commonly after about three months — helps determine whether the dose is working and whether to continue, increase or stop supplementation.
Avoid long‑term excess: Chronic excess iron can accumulate in organs and, over time, contribute to liver problems, diabetes, joint symptoms and heart issues. This is why testing and follow‑up are important.
Keep away from children: Iron tablets can be dangerous if swallowed by children. Store supplements securely out of reach.
Practical product guidance
Start with dietary approaches (red meat, poultry, fish, beans, lentils, fortified cereals, dark leafy greens) alongside any supplements.
For lower maintenance doses, there are many widely available options in the 15–30 mg range. For higher replacement doses (50–100 mg), there are over‑the‑counter products and prescription tablets. Some manufacturers offer third‑party testing; if you prefer that reassurance, look for brands with independent verification and clear labeling of elemental iron content.
If you experience intolerable side effects, talk with your clinician about changing the dose, switching forms (including protein‑bound iron), or considering prescription options.
Conclusion
Iron is vital for energy and blood health. Supplements are a useful tool when tests show low iron or anemia, but they are not harmless and should be used thoughtfully. Start by confirming your iron status with blood tests, try dietary improvements alongside any supplement, begin with the lowest effective dose for most people, and monitor response with repeat testing. If you have a known blood disorder, complex medical conditions, or persistent side effects, discuss management with your healthcare practitioner to choose the safest and most effective approach.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
Everything You Should Know About Iron Supplements
Iron often comes up in conversations about fatigue and blood health. Explore how iron functions in the body and why understanding iron status matters before supplementing.

Written by
Mito Team

Why iron matters
Iron is an essential mineral your body needs to make hemoglobin, the protein in red blood cells that carries oxygen around the body. Adequate iron supports energy, concentration, immune function and physical performance. When iron is low, people may feel unusually tired, have trouble concentrating or notice reduced physical stamina — and when deficiency progresses to anemia, hemoglobin falls and symptoms become more obvious.
How much iron do people need?
Recommended daily intakes vary by age, sex and life stage. Typical targets are about 8 mg per day for adult men and roughly 18 mg per day for pre‑menopausal, non‑pregnant women. Pregnant people and anyone with ongoing blood loss (for example, heavy menstrual bleeding, gastric bleeding) need more. People who eat only plant foods generally need more dietary iron because iron from plants (non‑heme iron) is absorbed less efficiently than iron from animal foods (heme iron) — commonly estimated around 1.8–2× higher dietary needs for vegetarians.
When to consider supplements
Confirmed deficiency: If blood tests show iron deficiency (low ferritin and/or low hemoglobin), targeted iron replacement is appropriate. In iron deficiency anemia, higher doses are commonly used to restore hemoglobin and iron stores.
Low iron without anemia: People can have low iron stores before anemia develops. Some may benefit from supplementation if they have symptoms such as unexplained fatigue, poor exercise tolerance or decreased concentration and low iron biomarkers.
Higher needs: Pregnancy, frequent blood donation, heavy menstrual loss or conditions that reduce absorption may justify supplement use.
When to avoid: If routine blood tests show normal iron stores, there is usually no benefit to continuing iron supplements. Certain conditions (for example, some genetic blood disorders such as thalassemia) can be associated with increased iron absorption — people with these conditions should generally avoid iron supplements unless they have documented iron deficiency and are being managed by a clinician.
Typical dosing
Maintenance / prevention: For people with mildly low stores or higher risk (for example, vegetarians) but normal hemoglobin, lower doses in the range of about 15–30 mg elemental iron daily are often sufficient when combined with dietary changes.
Replacement for iron deficiency anemia: Doses of 50–100 mg elemental iron once daily are commonly recommended to replace iron and correct anemia. These higher doses are prescribed until iron stores recover and hemoglobin normalizes.
Start low to reduce side effects: Because oral iron commonly causes stomach upset or constipation, it’s sensible for many people to begin at a lower dose and increase as tolerated while improving dietary iron intake at the same time.
Forms of iron
Heme vs non‑heme: Heme iron from animal sources is better absorbed than non‑heme iron from plants.
Iron salts: Common supplement forms include ferrous sulfate, ferrous gluconate and ferrous fumarate. These provide different amounts of elemental iron but are generally effective.
Slow‑release or enteric‑coated formulations: These may reduce gastrointestinal side effects for some people but can also reduce how much iron is absorbed and therefore slow correction of deficiency.
Specialized forms: Some products use iron bound to proteins (for example, iron protein succinylate) and may be easier on the gut for people who have persistent constipation with standard iron salts.
Tips to improve absorption and lower side effects
Take with vitamin C: Vitamin C (for example, a small glass of orange juice) increases absorption of non‑heme iron.
Avoid inhibitors around dosing: Tea, coffee, calcium‑rich foods and some high‑phytate foods can reduce absorption if consumed right with the iron dose. Aim to separate these by an hour or two when possible.
Food trade‑off: Taking iron with food usually reduces stomach upset but can lower absorption. Decide based on tolerance — better absorption on an empty stomach vs better tolerability with food.
Manage constipation and stomach upset: Drink plenty of water, eat a high‑fiber diet, and consider gentle bowel routines. If constipation continues, switching to a different iron form (for example, a protein‑bound form) or discussing a change of preparation with a clinician can help.
Slow‑release caution: If using slow‑release preparations to reduce side effects, be aware they may decrease the amount of iron absorbed and may need longer treatment to replenish stores.
Safety considerations and monitoring
Check before you start: It’s important to know your iron status (ferritin, hemoglobin) before beginning supplements. Taking iron when stores are adequate adds no benefit and may cause harm.
Repeat testing: If you start iron supplements, repeating blood tests — commonly after about three months — helps determine whether the dose is working and whether to continue, increase or stop supplementation.
Avoid long‑term excess: Chronic excess iron can accumulate in organs and, over time, contribute to liver problems, diabetes, joint symptoms and heart issues. This is why testing and follow‑up are important.
Keep away from children: Iron tablets can be dangerous if swallowed by children. Store supplements securely out of reach.
Practical product guidance
Start with dietary approaches (red meat, poultry, fish, beans, lentils, fortified cereals, dark leafy greens) alongside any supplements.
For lower maintenance doses, there are many widely available options in the 15–30 mg range. For higher replacement doses (50–100 mg), there are over‑the‑counter products and prescription tablets. Some manufacturers offer third‑party testing; if you prefer that reassurance, look for brands with independent verification and clear labeling of elemental iron content.
If you experience intolerable side effects, talk with your clinician about changing the dose, switching forms (including protein‑bound iron), or considering prescription options.
Conclusion
Iron is vital for energy and blood health. Supplements are a useful tool when tests show low iron or anemia, but they are not harmless and should be used thoughtfully. Start by confirming your iron status with blood tests, try dietary improvements alongside any supplement, begin with the lowest effective dose for most people, and monitor response with repeat testing. If you have a known blood disorder, complex medical conditions, or persistent side effects, discuss management with your healthcare practitioner to choose the safest and most effective approach.
Join Mito Health’s annual membership to test 100+ biomarkers with concierge-level support from your care team.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Recently published
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
What's included
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
What's included
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
What's included
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)
What could cost you $15,000? $349 with Mito.
No hidden fees. No subscription traps. Just real care.
Core Test - Comprehensive lab test covering 100+ biomarkers
Clinician reviewed insights and action plan
1:1 consultation with a real clinician
Upload past lab reports for lifetime tracking
Dedicated 1:1 health coaching
What's included
Duo Bundle (For 2)
Most popular
$798
$668
$130 off (17%)
Individual
$399
$349
$50 off (13%)



