Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Beyond Burnout: Understanding Adrenal Dysfunction

A clear guide to adrenal dysfunction and insufficiency: what they are, early signs, risks, and practical steps to stabilize energy and protect long-term health.

Written by

Gabriel Tan

Your adrenals sit above each kidney and help run stress responses, blood pressure and metabolism. When this system falls out of rhythm, you get two very different scenarios.

Adrenal dysfunction is the everyday pattern people describe as “wired and tired.” It is not a formal diagnosis. It usually reflects lifestyle stressors, poor sleep, and disrupted light exposure pushing the hypothalamic-pituitary-adrenal axis off its groove.

Adrenal insufficiency is different and medically defined. It means the body cannot make enough cortisol, either because the adrenals are damaged or because the signaling from brain to adrenals is impaired. Left unchecked, it can progress to adrenal crisis, an emergency.

What Goes Wrong When the System Slips?

Cortisol follows a daily curve. It should be higher in the morning to help you wake, then gradually fall toward evening so you can sleep.

When that curve flattens or flips, you feel it: grogginess on waking, salt cravings, lightheadedness on standing, brain fog, and unrefreshing sleep. Those patterns sit on the “dysfunction” end of the spectrum.

In adrenal insufficiency, warning signs are more specific: ongoing fatigue that does not lift with rest, unintentional weight loss, low blood pressure, and repeated “flu-like” days without a clear cause.

These symptoms overlap with many other conditions, which is why insufficiency is often missed early.

Why this matters

Cortisol is not a villain. In the right amount, it maintains blood pressure and glucose during routine stressors like illness, heat, or hard training.

Too little cortisol when the body is under strain can lead to an adrenal crisis with low blood pressure, shock, and risk of death if not treated quickly. That is rare, but it is the reason persistent red flags deserve attention rather than being filed under “just stressed.”

The Different Types of Insufficiency

Primary adrenal insufficiency most often results from autoimmune damage to the adrenal cortex. Less common causes include infections, bleeding into the glands, genetic conditions, or certain medications.

Secondary or tertiary insufficiency usually stems from impaired pituitary or hypothalamic signaling or from long-term use and abrupt withdrawal of glucocorticoids that suppress the axis.

Functional disruption without true insufficiency is usually a stack of inputs: sleep loss, erratic light exposure, frequent intense training without recovery, and micronutrient gaps that affect steroid hormone production.

A Reset For Adrenal Dysfunction Symptoms

If your pattern looks like everyday dysregulation rather than proven insufficiency, work the fundamentals for four to eight weeks. This is where most people feel a real lift.

Rebuild the daily cortisol curve

Anchor wake and wind-down times. Get outdoor light within an hour of waking, then keep evenings dim. This single habit improves the “high-a.m., low-p.m.” rhythm most people have lost.

Caffeine with care

Delay the first coffee 60 to 90 minutes after waking and avoid large hits after mid-afternoon. Pair caffeine with L-theanine if you’re jittery, and do not use it to skip meals.

Train smart, not brutal

If you feel flat, hold off on high-intensity work for a bit. Prioritize zone 2 cardio, strength training with longer rests, walking, mobility, and one true rest day. Volume plus recovery beats heroic spikes.

Mineral hygiene

Hydrate with a mix of water and electrolytes, especially sodium and potassium, and build meals that cover magnesium and B vitamins from whole foods. These inputs support normal cortisol synthesis and blood pressure stability.

Final Word

Your adrenal system is designed for rhythm. When life flattens that rhythm, you feel it as fog and restless nights.

The fix is not a single hack. It is a set of small moves that restore the morning-to-evening that helps you regain steady energy with those fundamentals.

Resources

  1. https://www.ncbi.nlm.nih.gov/books/NBK441832/

  2. https://www.ncbi.nlm.nih.gov/books/NBK279122/

  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC6297573/

Related Articles

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Beyond Burnout: Understanding Adrenal Dysfunction

A clear guide to adrenal dysfunction and insufficiency: what they are, early signs, risks, and practical steps to stabilize energy and protect long-term health.

Written by

Gabriel Tan

Your adrenals sit above each kidney and help run stress responses, blood pressure and metabolism. When this system falls out of rhythm, you get two very different scenarios.

Adrenal dysfunction is the everyday pattern people describe as “wired and tired.” It is not a formal diagnosis. It usually reflects lifestyle stressors, poor sleep, and disrupted light exposure pushing the hypothalamic-pituitary-adrenal axis off its groove.

Adrenal insufficiency is different and medically defined. It means the body cannot make enough cortisol, either because the adrenals are damaged or because the signaling from brain to adrenals is impaired. Left unchecked, it can progress to adrenal crisis, an emergency.

What Goes Wrong When the System Slips?

Cortisol follows a daily curve. It should be higher in the morning to help you wake, then gradually fall toward evening so you can sleep.

When that curve flattens or flips, you feel it: grogginess on waking, salt cravings, lightheadedness on standing, brain fog, and unrefreshing sleep. Those patterns sit on the “dysfunction” end of the spectrum.

In adrenal insufficiency, warning signs are more specific: ongoing fatigue that does not lift with rest, unintentional weight loss, low blood pressure, and repeated “flu-like” days without a clear cause.

These symptoms overlap with many other conditions, which is why insufficiency is often missed early.

Why this matters

Cortisol is not a villain. In the right amount, it maintains blood pressure and glucose during routine stressors like illness, heat, or hard training.

Too little cortisol when the body is under strain can lead to an adrenal crisis with low blood pressure, shock, and risk of death if not treated quickly. That is rare, but it is the reason persistent red flags deserve attention rather than being filed under “just stressed.”

The Different Types of Insufficiency

Primary adrenal insufficiency most often results from autoimmune damage to the adrenal cortex. Less common causes include infections, bleeding into the glands, genetic conditions, or certain medications.

Secondary or tertiary insufficiency usually stems from impaired pituitary or hypothalamic signaling or from long-term use and abrupt withdrawal of glucocorticoids that suppress the axis.

Functional disruption without true insufficiency is usually a stack of inputs: sleep loss, erratic light exposure, frequent intense training without recovery, and micronutrient gaps that affect steroid hormone production.

A Reset For Adrenal Dysfunction Symptoms

If your pattern looks like everyday dysregulation rather than proven insufficiency, work the fundamentals for four to eight weeks. This is where most people feel a real lift.

Rebuild the daily cortisol curve

Anchor wake and wind-down times. Get outdoor light within an hour of waking, then keep evenings dim. This single habit improves the “high-a.m., low-p.m.” rhythm most people have lost.

Caffeine with care

Delay the first coffee 60 to 90 minutes after waking and avoid large hits after mid-afternoon. Pair caffeine with L-theanine if you’re jittery, and do not use it to skip meals.

Train smart, not brutal

If you feel flat, hold off on high-intensity work for a bit. Prioritize zone 2 cardio, strength training with longer rests, walking, mobility, and one true rest day. Volume plus recovery beats heroic spikes.

Mineral hygiene

Hydrate with a mix of water and electrolytes, especially sodium and potassium, and build meals that cover magnesium and B vitamins from whole foods. These inputs support normal cortisol synthesis and blood pressure stability.

Final Word

Your adrenal system is designed for rhythm. When life flattens that rhythm, you feel it as fog and restless nights.

The fix is not a single hack. It is a set of small moves that restore the morning-to-evening that helps you regain steady energy with those fundamentals.

Resources

  1. https://www.ncbi.nlm.nih.gov/books/NBK441832/

  2. https://www.ncbi.nlm.nih.gov/books/NBK279122/

  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC6297573/

Related Articles

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Beyond Burnout: Understanding Adrenal Dysfunction

A clear guide to adrenal dysfunction and insufficiency: what they are, early signs, risks, and practical steps to stabilize energy and protect long-term health.

Written by

Gabriel Tan

Your adrenals sit above each kidney and help run stress responses, blood pressure and metabolism. When this system falls out of rhythm, you get two very different scenarios.

Adrenal dysfunction is the everyday pattern people describe as “wired and tired.” It is not a formal diagnosis. It usually reflects lifestyle stressors, poor sleep, and disrupted light exposure pushing the hypothalamic-pituitary-adrenal axis off its groove.

Adrenal insufficiency is different and medically defined. It means the body cannot make enough cortisol, either because the adrenals are damaged or because the signaling from brain to adrenals is impaired. Left unchecked, it can progress to adrenal crisis, an emergency.

What Goes Wrong When the System Slips?

Cortisol follows a daily curve. It should be higher in the morning to help you wake, then gradually fall toward evening so you can sleep.

When that curve flattens or flips, you feel it: grogginess on waking, salt cravings, lightheadedness on standing, brain fog, and unrefreshing sleep. Those patterns sit on the “dysfunction” end of the spectrum.

In adrenal insufficiency, warning signs are more specific: ongoing fatigue that does not lift with rest, unintentional weight loss, low blood pressure, and repeated “flu-like” days without a clear cause.

These symptoms overlap with many other conditions, which is why insufficiency is often missed early.

Why this matters

Cortisol is not a villain. In the right amount, it maintains blood pressure and glucose during routine stressors like illness, heat, or hard training.

Too little cortisol when the body is under strain can lead to an adrenal crisis with low blood pressure, shock, and risk of death if not treated quickly. That is rare, but it is the reason persistent red flags deserve attention rather than being filed under “just stressed.”

The Different Types of Insufficiency

Primary adrenal insufficiency most often results from autoimmune damage to the adrenal cortex. Less common causes include infections, bleeding into the glands, genetic conditions, or certain medications.

Secondary or tertiary insufficiency usually stems from impaired pituitary or hypothalamic signaling or from long-term use and abrupt withdrawal of glucocorticoids that suppress the axis.

Functional disruption without true insufficiency is usually a stack of inputs: sleep loss, erratic light exposure, frequent intense training without recovery, and micronutrient gaps that affect steroid hormone production.

A Reset For Adrenal Dysfunction Symptoms

If your pattern looks like everyday dysregulation rather than proven insufficiency, work the fundamentals for four to eight weeks. This is where most people feel a real lift.

Rebuild the daily cortisol curve

Anchor wake and wind-down times. Get outdoor light within an hour of waking, then keep evenings dim. This single habit improves the “high-a.m., low-p.m.” rhythm most people have lost.

Caffeine with care

Delay the first coffee 60 to 90 minutes after waking and avoid large hits after mid-afternoon. Pair caffeine with L-theanine if you’re jittery, and do not use it to skip meals.

Train smart, not brutal

If you feel flat, hold off on high-intensity work for a bit. Prioritize zone 2 cardio, strength training with longer rests, walking, mobility, and one true rest day. Volume plus recovery beats heroic spikes.

Mineral hygiene

Hydrate with a mix of water and electrolytes, especially sodium and potassium, and build meals that cover magnesium and B vitamins from whole foods. These inputs support normal cortisol synthesis and blood pressure stability.

Final Word

Your adrenal system is designed for rhythm. When life flattens that rhythm, you feel it as fog and restless nights.

The fix is not a single hack. It is a set of small moves that restore the morning-to-evening that helps you regain steady energy with those fundamentals.

Resources

  1. https://www.ncbi.nlm.nih.gov/books/NBK441832/

  2. https://www.ncbi.nlm.nih.gov/books/NBK279122/

  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC6297573/

Related Articles

Beyond Burnout: Understanding Adrenal Dysfunction

A clear guide to adrenal dysfunction and insufficiency: what they are, early signs, risks, and practical steps to stabilize energy and protect long-term health.

Written by

Gabriel Tan

Your adrenals sit above each kidney and help run stress responses, blood pressure and metabolism. When this system falls out of rhythm, you get two very different scenarios.

Adrenal dysfunction is the everyday pattern people describe as “wired and tired.” It is not a formal diagnosis. It usually reflects lifestyle stressors, poor sleep, and disrupted light exposure pushing the hypothalamic-pituitary-adrenal axis off its groove.

Adrenal insufficiency is different and medically defined. It means the body cannot make enough cortisol, either because the adrenals are damaged or because the signaling from brain to adrenals is impaired. Left unchecked, it can progress to adrenal crisis, an emergency.

What Goes Wrong When the System Slips?

Cortisol follows a daily curve. It should be higher in the morning to help you wake, then gradually fall toward evening so you can sleep.

When that curve flattens or flips, you feel it: grogginess on waking, salt cravings, lightheadedness on standing, brain fog, and unrefreshing sleep. Those patterns sit on the “dysfunction” end of the spectrum.

In adrenal insufficiency, warning signs are more specific: ongoing fatigue that does not lift with rest, unintentional weight loss, low blood pressure, and repeated “flu-like” days without a clear cause.

These symptoms overlap with many other conditions, which is why insufficiency is often missed early.

Why this matters

Cortisol is not a villain. In the right amount, it maintains blood pressure and glucose during routine stressors like illness, heat, or hard training.

Too little cortisol when the body is under strain can lead to an adrenal crisis with low blood pressure, shock, and risk of death if not treated quickly. That is rare, but it is the reason persistent red flags deserve attention rather than being filed under “just stressed.”

The Different Types of Insufficiency

Primary adrenal insufficiency most often results from autoimmune damage to the adrenal cortex. Less common causes include infections, bleeding into the glands, genetic conditions, or certain medications.

Secondary or tertiary insufficiency usually stems from impaired pituitary or hypothalamic signaling or from long-term use and abrupt withdrawal of glucocorticoids that suppress the axis.

Functional disruption without true insufficiency is usually a stack of inputs: sleep loss, erratic light exposure, frequent intense training without recovery, and micronutrient gaps that affect steroid hormone production.

A Reset For Adrenal Dysfunction Symptoms

If your pattern looks like everyday dysregulation rather than proven insufficiency, work the fundamentals for four to eight weeks. This is where most people feel a real lift.

Rebuild the daily cortisol curve

Anchor wake and wind-down times. Get outdoor light within an hour of waking, then keep evenings dim. This single habit improves the “high-a.m., low-p.m.” rhythm most people have lost.

Caffeine with care

Delay the first coffee 60 to 90 minutes after waking and avoid large hits after mid-afternoon. Pair caffeine with L-theanine if you’re jittery, and do not use it to skip meals.

Train smart, not brutal

If you feel flat, hold off on high-intensity work for a bit. Prioritize zone 2 cardio, strength training with longer rests, walking, mobility, and one true rest day. Volume plus recovery beats heroic spikes.

Mineral hygiene

Hydrate with a mix of water and electrolytes, especially sodium and potassium, and build meals that cover magnesium and B vitamins from whole foods. These inputs support normal cortisol synthesis and blood pressure stability.

Final Word

Your adrenal system is designed for rhythm. When life flattens that rhythm, you feel it as fog and restless nights.

The fix is not a single hack. It is a set of small moves that restore the morning-to-evening that helps you regain steady energy with those fundamentals.

Resources

  1. https://www.ncbi.nlm.nih.gov/books/NBK441832/

  2. https://www.ncbi.nlm.nih.gov/books/NBK279122/

  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC6297573/

Related Articles

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

What could cost you $15,000? $349 with Mito.

No hidden fees. No subscription traps. Just real care.

What's included

Core Test - Comprehensive lab test covering 100+ biomarkers

Clinician reviewed insights and action plan

1:1 consultation with a real clinician

Upload past lab reports for lifetime tracking

Dedicated 1:1 health coaching

Duo Bundle (For 2)

Most popular

$798

$668

$130 off (17%)

Individual

$399

$349

$50 off (13%)

What could cost you $15,000? $349 with Mito.

No hidden fees. No subscription traps. Just real care.

What's included

Core Test - Comprehensive lab test covering 100+ biomarkers

Clinician reviewed insights and action plan

1:1 consultation with a real clinician

Upload past lab reports for lifetime tracking

Dedicated 1:1 health coaching

Duo Bundle (For 2)

Most popular

$798

$668

$130 off (17%)

Individual

$399

$349

$50 off (13%)

What could cost you $15,000? $349 with Mito.

No hidden fees. No subscription traps. Just real care.

What's included

Core Test - Comprehensive lab test covering 100+ biomarkers

Clinician reviewed insights and action plan

1:1 consultation with a real clinician

Upload past lab reports for lifetime tracking

Dedicated 1:1 health coaching

Duo Bundle (For 2)

Most popular

$798

$668

$130 off (17%)

Individual

$399

$349

$50 off (13%)

What could cost you $15,000? $349 with Mito.

No hidden fees. No subscription traps. Just real care.

Core Test - Comprehensive lab test covering 100+ biomarkers

Clinician reviewed insights and action plan

1:1 consultation with a real clinician

Upload past lab reports for lifetime tracking

Dedicated 1:1 health coaching

What's included

Duo Bundle (For 2)

Most popular

$798

$668

$130 off (17%)

Individual

$399

$349

$50 off (13%)

10x more value at a fraction of the walk-in price.

10x more value at a fraction of
the walk-in price.

10x more value at a fraction of the walk-in price.

10x more value at a fraction of the walk-in price.

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.