Your guide to DPA.
Discover the role of DPA in your health and longevity with Mito Health's advanced biomarker analysis. Our detailed reports cover key biomarkers, providing essential insights to help you make informed decisions for a healthier, longer life.
What is DPA?
DPA (docosapentaenoic acid) is an omega-3 fatty acid that is less well-known compared to EPA and DHA but still plays an important role in health.
DPA is found in certain fish and animal products and is produced in small amounts in the body from EPA.
It is a long-chain polyunsaturated fatty acid (PUFA) that is part of the omega-3 family, and it shares many of the health benefits of EPA and DHA, although it is considered less potent in some cases.
What does it assess?
DPA levels assess an individual’s omega-3 fatty acid status, specifically its role in reducing inflammation, improving cardiovascular health, and promoting overall cellular function. DPA may be particularly important for those looking to optimize the anti-inflammatory effects of omega-3s.
DPA has been shown to have a strong anti-inflammatory effect and may contribute to improved vascular health, potentially supporting blood vessel function and reducing the risk of atherosclerosis (plaque buildup in arteries).
It may also play a role in supporting brain health, although research on DPA's specific cognitive benefits is still emerging.
How do I optimize my DPA levels?
Fatty fish like salmon, mackerel, sardines, and anchovies are excellent sources of DPA, along with EPA and DHA.
Besides fish, plant-based omega-3s (ALA) found in foods like flaxseeds, chia seeds, walnuts, and hemp seeds can be converted to EPA and, to a lesser extent, DPA in the body.
While not as efficient as direct fish or fish oil sources, these plant-based foods can support overall omega-3 status.
For vegetarians or those who avoid fish, algal oil can provide omega-3s, including DPA.
Algal oil supplements are plant-based and are a good alternative to fish-based sources of DPA.
What do high and low DPA levels mean?
High DPA levels are typically associated with better inflammation control, improved vascular health, and enhanced cardiovascular protection.
Higher DPA levels may suggest that your body is in a favorable state for managing inflammation and oxidative stress.
Low DPA levels can be a sign of insufficient omega-3 intake or poor conversion of EPA into DPA. This can indicate an increased risk for chronic inflammation, cardiovascular issues, and less optimal brain health.
Low levels of DPA may also be reflective of low overall omega-3 consumption or an imbalance in fatty acid intake, particularly if omega-6 fatty acids are consuming too much of the body’s metabolic resources.
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