May 21, 2025
How to Reduce Chronic Inflammation Naturally: Vitamins, Nutrition, & Lifestyle Changes
Your simple guide to daily supplements, lifestyle tips, and food choices that actually work to reduce your chronic inflammation.
Written by
Mito Team
Feeling tired, foggy, or inflamed without a clear reason? You’re not alone. Chronic inflammation affects an estimated 60% of Americans and plays a role in everything from fatigue and gut issues to migraines, joint pain, and long-term health risks.
Chronic Inflammation: What Causes It
Chronic inflammation happens when your immune system stays switched on long after the initial problem is gone. Instead of healing, it creates a low-grade, ongoing fire in your body.
Over time, this can damage tissues and raise your risk for conditions like heart disease, type 2 diabetes, Crohn’s disease, and IBD. Inflammation is also linked with brain fog, fatigue, and autoimmune disorders.
Some common triggers of inflammation in the body include:
Poor diet (too much sugar, processed food, or alcohol)
Chronic stress
Sleep issues
Sedentary lifestyle
Nutrient deficiencies
Gut imbalances or food sensitivities (like gluten)
What Can You Do to Reduce Inflammation in the Body?
Reducing inflammation starts with focusing on three areas: what you eat, the supplements you take, and the habits you practice daily.
1. Add more anti-inflammatory foods
Certain foods naturally fight inflammation. Focus on adding more of these to your daily meals:
Fatty fish (salmon, sardines, mackerel)
Leafy greens (spinach, kale, arugula)
Berries and other colorful fruits
Olive oil and avocado
Nuts and seeds
Herbs and spices like turmeric and ginger
If you suspect gluten might be triggering symptoms like bloating or brain fog, it’s worth testing a gluten-free trial. One case study showed major improvement after cutting out gluten, including better digestion and clearer thinking.
2. Consider inflammation-fighting supplements
Food is powerful, but sometimes you need a little extra help. That’s where health supplements come in. Here are a few of the most researched supplements to reduce inflammation:
Omega-3 Fatty Acids: Found in fish oil, omega-3s help calm inflammation in the brain and nervous system. They’re especially helpful for people with mood issues, brain fog, or chronic pain.
Vitamin D3 + K2: Low vitamin D is strongly linked to chronic inflammation and poor immune function. When paired with vitamin K2, D3 supports bone health and reduces inflammatory markers.
Curcumin (from turmeric): Curcumin is one of the best-known supplements for inflammation. It’s proven to help with migraines and other inflammatory conditions, especially when taken with black pepper for better absorption.
Magnesium: Magnesium supplements helps calm the nervous system and support muscle function. Low levels are common and can make inflammation worse, especially in people with gut disorders.
Melatonin: While mostly known as a sleep supplement, melatonin also has anti-inflammatory properties. However, it may worsen gut issues for some, so a personalized approach is best.
Too low or too high levels of these nutrients in your body can cause inflammation. At Mito Health, we help you figure out which nutrition supplements are right for your body—using lab testing, not guesswork.
3. Make small lifestyle changes that lower inflammation
Even small changes in your daily routine can lower inflammation levels:
Try intermittent fasting: Fasting windows (like 16:8) help reduce inflammatory markers like hs-CRP and IL-6. They also give your gut time to rest and reset.
Move your body: You don’t need intense workouts. Just 30 minutes of walking or light strength training a few times a week can improve immune balance and reduce chronic inflammation.
Try cold showers: Cold water immersion may reduce pain and inflammation for people with migraines, Crohn’s, or fatigue. Start with 30 seconds and work your way up.
Get sunlight (safely): Sunlight helps your body produce vitamin D, a key player in immune regulation. Aim for 10 to 20 minutes of sun exposure daily, or supplement if needed.
Why Personalized Supplements Work Better
Many people try random supplements without knowing what their body actually needs, wasting time and money. Worse, the wrong supplement could backfire.
That’s why Mito Health takes a different approach. We start with comprehensive blood testing to measure your inflammation markers, nutrient levels, and overall health status. Then, our health expert analyzes your results, explains what’s driving your symptoms, and helps you choose the right wellness supplements and lifestyle plan.
When you join, you’ll get:
A personalized health dashboard
1:1 onboarding with a clinical expert
Data-driven insights and progress tracking
Add-on testing for hormones, gut health, and more
You Don’t Have To Live With Inflammation
Chronic inflammation doesn’t always scream for attention, but it quietly wears you down. The good news is, you can take control with the right food, vitamin supplements, and daily habits.
Mito Health gives you the tools to reduce inflammation from the inside out, with expert guidance, lab testing, and personalized plans tailored to you.