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Understand Your BUN/Creatinine Ratio and Its Role in Health
Discover the importance of the BUN/Creatinine ratio in evaluating kidney function, with clear explanations of normal, low, and high levels.

Written by
Mito Team

What is the BUN/Creatinine Ratio?
The BUN/creatinine ratio is a measurement comparing blood urea nitrogen (BUN) levels to creatinine levels.Both BUN and creatinine are waste products excreted by the kidneys; BUN comes from protein breakdown, while creatinine results from muscle metabolism.This ratio is commonly used to assess kidney function and differentiate between various causes of kidney-related abnormalities.
What does it asses?
The BUN/creatinine ratio assesses the relationship between urea and creatinine clearance to identify potential kidney function issues or disruptions in protein metabolism.The ratio can also help differentiate between causes of kidney dysfunction, such as distinguishing between prerenal (before the kidneys) and intrinsic renal (within the kidneys) causes.
How do I optimize my BUN/Creatinine Ratio?
Adequate hydration is key, as dehydration can elevate BUN levels and increase the BUN/creatinine ratio.Drinking enough water throughout the day helps maintain optimal kidney filtration and waste excretion. Consuming moderate protein levels suited to your body’s needs helps prevent excessive urea production.High protein diets may increase BUN levels, especially in individuals with compromised kidney function. Certain medications, such as NSAIDs, and substances like alcohol can negatively impact kidney function.Avoiding or limiting these can support healthier BUN and creatinine levels and, consequently, an optimal ratio.
What does a high and low BUN/Creatinine Ratio mean?
An elevated ratio may suggest dehydration, as reduced fluid levels cause BUN concentration to rise. High ratios may also indicate heart conditions, high protein diets, or gastrointestinal bleeding, where protein breakdown produces more urea.A low ratio can be seen in cases of liver disease, where urea production is reduced. It may also indicate malnutrition, where low protein intake results in lower BUN levels, or in cases of advanced kidney disease where creatinine clearance is impaired.
Related MitoHealth Reads
https://mitohealth.com/improve/how-to-improve-your-bun-creatinine-ratio-naturally
Understand Your BUN/Creatinine Ratio and Its Role in Health
Discover the importance of the BUN/Creatinine ratio in evaluating kidney function, with clear explanations of normal, low, and high levels.

Written by
Mito Team

What is the BUN/Creatinine Ratio?
The BUN/creatinine ratio is a measurement comparing blood urea nitrogen (BUN) levels to creatinine levels.Both BUN and creatinine are waste products excreted by the kidneys; BUN comes from protein breakdown, while creatinine results from muscle metabolism.This ratio is commonly used to assess kidney function and differentiate between various causes of kidney-related abnormalities.
What does it asses?
The BUN/creatinine ratio assesses the relationship between urea and creatinine clearance to identify potential kidney function issues or disruptions in protein metabolism.The ratio can also help differentiate between causes of kidney dysfunction, such as distinguishing between prerenal (before the kidneys) and intrinsic renal (within the kidneys) causes.
How do I optimize my BUN/Creatinine Ratio?
Adequate hydration is key, as dehydration can elevate BUN levels and increase the BUN/creatinine ratio.Drinking enough water throughout the day helps maintain optimal kidney filtration and waste excretion. Consuming moderate protein levels suited to your body’s needs helps prevent excessive urea production.High protein diets may increase BUN levels, especially in individuals with compromised kidney function. Certain medications, such as NSAIDs, and substances like alcohol can negatively impact kidney function.Avoiding or limiting these can support healthier BUN and creatinine levels and, consequently, an optimal ratio.
What does a high and low BUN/Creatinine Ratio mean?
An elevated ratio may suggest dehydration, as reduced fluid levels cause BUN concentration to rise. High ratios may also indicate heart conditions, high protein diets, or gastrointestinal bleeding, where protein breakdown produces more urea.A low ratio can be seen in cases of liver disease, where urea production is reduced. It may also indicate malnutrition, where low protein intake results in lower BUN levels, or in cases of advanced kidney disease where creatinine clearance is impaired.
Related MitoHealth Reads
https://mitohealth.com/improve/how-to-improve-your-bun-creatinine-ratio-naturally
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Understand Your BUN/Creatinine Ratio and Its Role in Health
Discover the importance of the BUN/Creatinine ratio in evaluating kidney function, with clear explanations of normal, low, and high levels.

Written by
Mito Team

What is the BUN/Creatinine Ratio?
The BUN/creatinine ratio is a measurement comparing blood urea nitrogen (BUN) levels to creatinine levels.Both BUN and creatinine are waste products excreted by the kidneys; BUN comes from protein breakdown, while creatinine results from muscle metabolism.This ratio is commonly used to assess kidney function and differentiate between various causes of kidney-related abnormalities.
What does it asses?
The BUN/creatinine ratio assesses the relationship between urea and creatinine clearance to identify potential kidney function issues or disruptions in protein metabolism.The ratio can also help differentiate between causes of kidney dysfunction, such as distinguishing between prerenal (before the kidneys) and intrinsic renal (within the kidneys) causes.
How do I optimize my BUN/Creatinine Ratio?
Adequate hydration is key, as dehydration can elevate BUN levels and increase the BUN/creatinine ratio.Drinking enough water throughout the day helps maintain optimal kidney filtration and waste excretion. Consuming moderate protein levels suited to your body’s needs helps prevent excessive urea production.High protein diets may increase BUN levels, especially in individuals with compromised kidney function. Certain medications, such as NSAIDs, and substances like alcohol can negatively impact kidney function.Avoiding or limiting these can support healthier BUN and creatinine levels and, consequently, an optimal ratio.
What does a high and low BUN/Creatinine Ratio mean?
An elevated ratio may suggest dehydration, as reduced fluid levels cause BUN concentration to rise. High ratios may also indicate heart conditions, high protein diets, or gastrointestinal bleeding, where protein breakdown produces more urea.A low ratio can be seen in cases of liver disease, where urea production is reduced. It may also indicate malnutrition, where low protein intake results in lower BUN levels, or in cases of advanced kidney disease where creatinine clearance is impaired.
Related MitoHealth Reads
https://mitohealth.com/improve/how-to-improve-your-bun-creatinine-ratio-naturally
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Understand Your BUN/Creatinine Ratio and Its Role in Health
Discover the importance of the BUN/Creatinine ratio in evaluating kidney function, with clear explanations of normal, low, and high levels.

Written by
Mito Team

What is the BUN/Creatinine Ratio?
The BUN/creatinine ratio is a measurement comparing blood urea nitrogen (BUN) levels to creatinine levels.Both BUN and creatinine are waste products excreted by the kidneys; BUN comes from protein breakdown, while creatinine results from muscle metabolism.This ratio is commonly used to assess kidney function and differentiate between various causes of kidney-related abnormalities.
What does it asses?
The BUN/creatinine ratio assesses the relationship between urea and creatinine clearance to identify potential kidney function issues or disruptions in protein metabolism.The ratio can also help differentiate between causes of kidney dysfunction, such as distinguishing between prerenal (before the kidneys) and intrinsic renal (within the kidneys) causes.
How do I optimize my BUN/Creatinine Ratio?
Adequate hydration is key, as dehydration can elevate BUN levels and increase the BUN/creatinine ratio.Drinking enough water throughout the day helps maintain optimal kidney filtration and waste excretion. Consuming moderate protein levels suited to your body’s needs helps prevent excessive urea production.High protein diets may increase BUN levels, especially in individuals with compromised kidney function. Certain medications, such as NSAIDs, and substances like alcohol can negatively impact kidney function.Avoiding or limiting these can support healthier BUN and creatinine levels and, consequently, an optimal ratio.
What does a high and low BUN/Creatinine Ratio mean?
An elevated ratio may suggest dehydration, as reduced fluid levels cause BUN concentration to rise. High ratios may also indicate heart conditions, high protein diets, or gastrointestinal bleeding, where protein breakdown produces more urea.A low ratio can be seen in cases of liver disease, where urea production is reduced. It may also indicate malnutrition, where low protein intake results in lower BUN levels, or in cases of advanced kidney disease where creatinine clearance is impaired.
Related MitoHealth Reads
https://mitohealth.com/improve/how-to-improve-your-bun-creatinine-ratio-naturally
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1:1 Consultation
Meet with your dedicated care team to review your results and define next steps

Lifetime health record tracking
Upload past labs and monitor your progress over time

Biological age analysis
See how your body is aging and what’s driving it

Order add-on tests and scans anytime
Access to advanced diagnostics at discounted rates for members
Concierge-level care, made accessible.
Exclusive offer. Save $50.
Codeveloped with experts at MIT & Stanford
Less than $1/ day
Billed annually - cancel anytime
Bundle options:
Individual
$399
$349
/year
or 4 interest-free payments of $87.25*
Duo Bundle (For 2)
$798
$668
/year
or 4 interest-free payments of $167*
Pricing for members in NY, NJ & RI may vary.

Checkout with HSA/FSA
Secure, private platform
What's included

Comprehensive lab testing (Core)
100+ biomarkers - Test at 2,000+ labs nationwide

In-depth health insights & action plan
Expert designed recommendations across exercise, nutrition, and supplements

1:1 Consultation
Meet with your dedicated care team to review your results and define next steps

Lifetime health record tracking
Upload past labs and monitor your progress over time

Biological age analysis
See how your body is aging and what’s driving it

Order add-on tests and scans anytime
Access to advanced diagnostics at discounted rates for members
Concierge-level care, made accessible.
Exclusive offer. Save $50.
Codeveloped with experts at MIT & Stanford
Less than $1/ day
Billed annually - cancel anytime
Bundle options:
Individual
$399
$349
/year
or 4 payments of $87.25*
Duo Bundle
(For 2)
$798
$668
/year
or 4 payments of $167*
Pricing for members in NY, NJ & RI may vary.

Checkout with HSA/FSA
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