Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Homocysteine Levels: A Critical Biomarker for Heart & Brain Health
Homocysteine is an amino acid linked to cardiovascular disease, stroke, and cognitive decline. Elevated homocysteine levels may result from vitamin deficiencies (B6, B9, B12), poor diet, or genetic factors. This guide covers how to test homocysteine levels, what high levels mean, and how to reduce risks through proper nutrition and targeted supplementation. Learn why homocysteine testing is a key part of heart and brain health management.

Written by
Mito Team

What is Homocysteine?
Homocysteine is an important amino-acid produced by our body from another amino-acid, methionine, as part of the process of methylation.
What does it assess?
Homocysteine is normally excreted in the urine or recycled back into other amino acids, a process that is mainly regulated by B vitamins and betaine. High levels have been associated with oxidative stress and inflammation, cognitive decline and heart disease.
How do I optimize my Homocysteine levels?
Homocysteine metabolism is dependent on vitamins B6, B12, and folate. These vitamins help convert homocysteine into less harmful substances like methionine and cysteine. Ensure your diet includes folate-rich foods, B12-rich foods, and B6-rich foods. If dietary intake is insufficient, consider supplementation after consulting a healthcare provider. Excessive alcohol intake can interfere with the absorption and metabolism of B vitamins, contributing to elevated homocysteine levels. Reducing alcohol intake can help optimize B vitamin levels and subsequently support homocysteine balance. Chronic inflammation and high stress can elevate homocysteine levels. Reducing chronic inflammation through a healthy diet, regular exercise, and stress management techniques can help maintain normal homocysteine levels.
What do high and low Homocysteine levels mean?
High homocysteine levels can be due to inadequate intake of vitamins B6, B9 (folate) and B12, as well as inadequate choline and betaine intake in the diet. Additionally, certain genetic mutations (relating to the MTHFR gene) affect how well our body is able to metabolise homocysteine. Higher levels are associated with increased risk of cardiovascular disease and cognitive decline.Having low homocysteine levels in the blood is generally considered healthy and is not typically a cause for concern. Low levels of homocysteine are associated with better cardiovascular and cognitive health.
Related MitoHealth Reads
https://mitohealth.com/symptom-levels/symptoms-of-high-homocysteine
https://mitohealth.com/improve/how-to-improve-your-homocysteine-naturally
https://mitohealth.com/blog/homocysteine-biomarker-longevity-40s-heart-disease
Homocysteine Levels: A Critical Biomarker for Heart & Brain Health
Homocysteine is an amino acid linked to cardiovascular disease, stroke, and cognitive decline. Elevated homocysteine levels may result from vitamin deficiencies (B6, B9, B12), poor diet, or genetic factors. This guide covers how to test homocysteine levels, what high levels mean, and how to reduce risks through proper nutrition and targeted supplementation. Learn why homocysteine testing is a key part of heart and brain health management.

Written by
Mito Team

What is Homocysteine?
Homocysteine is an important amino-acid produced by our body from another amino-acid, methionine, as part of the process of methylation.
What does it assess?
Homocysteine is normally excreted in the urine or recycled back into other amino acids, a process that is mainly regulated by B vitamins and betaine. High levels have been associated with oxidative stress and inflammation, cognitive decline and heart disease.
How do I optimize my Homocysteine levels?
Homocysteine metabolism is dependent on vitamins B6, B12, and folate. These vitamins help convert homocysteine into less harmful substances like methionine and cysteine. Ensure your diet includes folate-rich foods, B12-rich foods, and B6-rich foods. If dietary intake is insufficient, consider supplementation after consulting a healthcare provider. Excessive alcohol intake can interfere with the absorption and metabolism of B vitamins, contributing to elevated homocysteine levels. Reducing alcohol intake can help optimize B vitamin levels and subsequently support homocysteine balance. Chronic inflammation and high stress can elevate homocysteine levels. Reducing chronic inflammation through a healthy diet, regular exercise, and stress management techniques can help maintain normal homocysteine levels.
What do high and low Homocysteine levels mean?
High homocysteine levels can be due to inadequate intake of vitamins B6, B9 (folate) and B12, as well as inadequate choline and betaine intake in the diet. Additionally, certain genetic mutations (relating to the MTHFR gene) affect how well our body is able to metabolise homocysteine. Higher levels are associated with increased risk of cardiovascular disease and cognitive decline.Having low homocysteine levels in the blood is generally considered healthy and is not typically a cause for concern. Low levels of homocysteine are associated with better cardiovascular and cognitive health.
Related MitoHealth Reads
https://mitohealth.com/symptom-levels/symptoms-of-high-homocysteine
https://mitohealth.com/improve/how-to-improve-your-homocysteine-naturally
https://mitohealth.com/blog/homocysteine-biomarker-longevity-40s-heart-disease
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Homocysteine Levels: A Critical Biomarker for Heart & Brain Health
Homocysteine is an amino acid linked to cardiovascular disease, stroke, and cognitive decline. Elevated homocysteine levels may result from vitamin deficiencies (B6, B9, B12), poor diet, or genetic factors. This guide covers how to test homocysteine levels, what high levels mean, and how to reduce risks through proper nutrition and targeted supplementation. Learn why homocysteine testing is a key part of heart and brain health management.

Written by
Mito Team

What is Homocysteine?
Homocysteine is an important amino-acid produced by our body from another amino-acid, methionine, as part of the process of methylation.
What does it assess?
Homocysteine is normally excreted in the urine or recycled back into other amino acids, a process that is mainly regulated by B vitamins and betaine. High levels have been associated with oxidative stress and inflammation, cognitive decline and heart disease.
How do I optimize my Homocysteine levels?
Homocysteine metabolism is dependent on vitamins B6, B12, and folate. These vitamins help convert homocysteine into less harmful substances like methionine and cysteine. Ensure your diet includes folate-rich foods, B12-rich foods, and B6-rich foods. If dietary intake is insufficient, consider supplementation after consulting a healthcare provider. Excessive alcohol intake can interfere with the absorption and metabolism of B vitamins, contributing to elevated homocysteine levels. Reducing alcohol intake can help optimize B vitamin levels and subsequently support homocysteine balance. Chronic inflammation and high stress can elevate homocysteine levels. Reducing chronic inflammation through a healthy diet, regular exercise, and stress management techniques can help maintain normal homocysteine levels.
What do high and low Homocysteine levels mean?
High homocysteine levels can be due to inadequate intake of vitamins B6, B9 (folate) and B12, as well as inadequate choline and betaine intake in the diet. Additionally, certain genetic mutations (relating to the MTHFR gene) affect how well our body is able to metabolise homocysteine. Higher levels are associated with increased risk of cardiovascular disease and cognitive decline.Having low homocysteine levels in the blood is generally considered healthy and is not typically a cause for concern. Low levels of homocysteine are associated with better cardiovascular and cognitive health.
Related MitoHealth Reads
https://mitohealth.com/symptom-levels/symptoms-of-high-homocysteine
https://mitohealth.com/improve/how-to-improve-your-homocysteine-naturally
https://mitohealth.com/blog/homocysteine-biomarker-longevity-40s-heart-disease
Mito Health: Helping you live healthier, longer.
In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.
Homocysteine Levels: A Critical Biomarker for Heart & Brain Health
Homocysteine is an amino acid linked to cardiovascular disease, stroke, and cognitive decline. Elevated homocysteine levels may result from vitamin deficiencies (B6, B9, B12), poor diet, or genetic factors. This guide covers how to test homocysteine levels, what high levels mean, and how to reduce risks through proper nutrition and targeted supplementation. Learn why homocysteine testing is a key part of heart and brain health management.

Written by
Mito Team

What is Homocysteine?
Homocysteine is an important amino-acid produced by our body from another amino-acid, methionine, as part of the process of methylation.
What does it assess?
Homocysteine is normally excreted in the urine or recycled back into other amino acids, a process that is mainly regulated by B vitamins and betaine. High levels have been associated with oxidative stress and inflammation, cognitive decline and heart disease.
How do I optimize my Homocysteine levels?
Homocysteine metabolism is dependent on vitamins B6, B12, and folate. These vitamins help convert homocysteine into less harmful substances like methionine and cysteine. Ensure your diet includes folate-rich foods, B12-rich foods, and B6-rich foods. If dietary intake is insufficient, consider supplementation after consulting a healthcare provider. Excessive alcohol intake can interfere with the absorption and metabolism of B vitamins, contributing to elevated homocysteine levels. Reducing alcohol intake can help optimize B vitamin levels and subsequently support homocysteine balance. Chronic inflammation and high stress can elevate homocysteine levels. Reducing chronic inflammation through a healthy diet, regular exercise, and stress management techniques can help maintain normal homocysteine levels.
What do high and low Homocysteine levels mean?
High homocysteine levels can be due to inadequate intake of vitamins B6, B9 (folate) and B12, as well as inadequate choline and betaine intake in the diet. Additionally, certain genetic mutations (relating to the MTHFR gene) affect how well our body is able to metabolise homocysteine. Higher levels are associated with increased risk of cardiovascular disease and cognitive decline.Having low homocysteine levels in the blood is generally considered healthy and is not typically a cause for concern. Low levels of homocysteine are associated with better cardiovascular and cognitive health.
Related MitoHealth Reads
https://mitohealth.com/symptom-levels/symptoms-of-high-homocysteine
https://mitohealth.com/improve/how-to-improve-your-homocysteine-naturally
https://mitohealth.com/blog/homocysteine-biomarker-longevity-40s-heart-disease
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$798
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Trusted by thousands of members
What could cost you $15,000? $349 with Mito.
What's included

Comprehensive Lab Test (Core)
100+ biomarkers - Test at 2,000+ lab locations nationwide

Clinician reviewed insights & Action Plan
Complete with exercise, nutrition, and supplement recommendations

1:1 Clinician consult
Receive expert guidance on how to manage and reduce your health risks

Upload past labs for lifetime tracking
All your medical records in one secure dashboard

Biological age
Understand your biological age and track your pace of aging

Access to advanced diagnostics
Customize your plan with optional advanced blood tests and scans
Premium care made accessible.
HSA/FSA eligible
One-time payment
No hidden fees or subscription traps
Buy more & save:
Individual
$50 off (Save 13%)
$349
$399
Duo Bundle (For 2)
$334 per person
$668
$798
popular
★ ★ ★ ★ ★
Trusted by thousands of members
What could cost you $15,000? $349 with Mito.
What's included

Comprehensive Lab Test (Core)
100+ biomarkers - Test at 2,000+ lab locations nationwide

Clinician reviewed insights & Action Plan
Complete with exercise, nutrition, and supplement recommendations

1:1 Clinician consult
Receive expert guidance on how to manage and reduce your health risks

Upload past labs for lifetime tracking
All your medical records in one secure dashboard

Biological age
Understand your biological age and track your pace of aging

Access to advanced diagnostics
Customize your plan with optional advanced blood tests and scans
Premium care made accessible.
HSA/FSA eligible
One-time payment
No hidden fees or subscription traps
Buy more & save:
Individual
$50 off (Save 13%)
$349
$399
Duo Bundle (For 2)
$334 per person
$668
$798
popular
★ ★ ★ ★ ★
Trusted by thousands of members