Your guide to Gamma-glutamyl Transferase.
Discover the role of Gamma-glutamyl Transferase (GGT) in your health and longevity with Mito Health's advanced biomarker analysis. Our detailed reports cover key biomarkers, providing essential insights to help you make informed decisions for a healthier, longer life.
What is Gamma-glutamyl Transferase (GGT)?
Gamma-glutamyl Transferase (GGT) is an enzyme found in various tissues throughout the body, with particularly high levels in the liver.
GGT plays a role in the metabolism of glutathione, an antioxidant that helps protect cells from damage caused by oxidative stress.
When liver cells are damaged or inflamed, GGT is released into the bloodstream, where it can be detected through blood tests.
What does it assess?
GGT levels are closely related to your healthspan, because they serve as a marker of liver health and overall oxidative stress in the body.
Monitoring GGT levels can help identify liver dysfunction and oxidative stress early, allowing for interventions to prevent further damage and maintain overall healthspan.
How do I optimize my Gamma-glutamyl Transferase (GGT) levels?
Excessive alcohol intake is one of the most common causes of elevated GGT.
Reducing or eliminating alcohol consumption can help lower GGT levels and protect liver health.
A balanced diet rich in antioxidants (such as vitamins C and E) can support liver function and reduce oxidative stress, which may help regulate GGT levels.
High levels of cholesterol and body fat can contribute to liver stress and elevated GGT.
A diet low in saturated fats, along with regular exercise, can help optimize lipid metabolism and liver health.
What do high and low Gamma-glutamyl Transferase (GGT) levels mean?
Elevated GGT levels typically indicate liver or bile duct dysfunction. Conditions such as alcoholic liver disease, hepatitis, cirrhosis, and bile duct obstructions (such as gallstones) are common causes.
GGT can also be elevated in cases of chronic alcohol use or after heavy drinking, even without liver disease.
Low levels of GGT are generally not a concern and are typically seen in healthy individuals.
A decrease in GGT is not usually linked to any specific health condition, and low levels do not typically require intervention.