What is Aspartate Transaminase (AST)?

Aspartate Aminotransferase (AST) is an enzyme found in various tissues throughout the body, with particularly high levels in the liver and heart.‍It plays a crucial role in amino acid metabolism and energy production within cells.‍When AST-containing cells are damaged or destroyed, AST is released into the bloodstream, where it can be detected through blood tests.

What does it assess?

AST levels are closely related to your healthspan because they serve as a marker of tissue health, particularly in the liver and heart.‍Monitoring AST levels can help identify tissue damage early, allowing for timely intervention and management to prevent further damage and maintain overall healthspan.

How do I optimize my Aspartate Transaminase (AST) levels?

Avoid excessive alcohol consumption and limit exposure to toxins that can damage the liver. A balanced diet, rich in fruits, vegetables, and antioxidants, supports liver function and may help lower AST levels. Engaging in regular physical activity promotes overall health and helps maintain healthy muscle function, which may prevent muscle-related AST elevation. Conditions such as obesity, diabetes, and metabolic syndrome can contribute to liver stress and elevated AST levels.‍Managing these conditions through a balanced diet, regular exercise, and proper medication can help normalize AST levels.

What do high and low Aspartate Transaminase (AST) levels mean?

Elevated AST levels usually indicate tissue damage, particularly in the liver, heart, or muscles. Common causes of increased AST include liver diseases, alcohol abuse, heart attacks (myocardial infarction), and muscle disorders.‍Low AST levels are typically not a concern and do not usually indicate any specific health issue. In fact, some studies suggest that low levels may be associated with certain health benefits, such as a lower risk of liver disease or better overall metabolic health.